| Basic Information | |
|---|---|
| Species | Arabidopsis thaliana |
| Cazyme ID | AT1G70290.1 |
| Family | GT20 |
| Protein Properties | Length: 857 Molecular Weight: 97561.2 Isoelectric Point: 5.726 |
| Chromosome | Chromosome/Scaffold: 1 Start: 26471078 End: 26474786 |
| Description | trehalose-6-phosphate synthase, putative, expressed |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT20 | 55 | 541 | 0 |
| SRERKIIVANMLPLQSKRDAETGKWCFNWDEDSLQLQLRDGFSSETEFLYVGSLNVDIETNEQEEVSQKLLEEFNCVATFLSQELQEMFYLGFCKHQLWP LFHYMLPMFPDHGDRFDRRLWQAYVSANKIFSDRVMEVINPEDDYVWIQDYHLMVLPTFLRKRFNRIKLGFFLHSPFPSSEIYRTLPVRDEILRGLLNCD LIGFHTFDYARHFLSCCSRMLGLDYESKRGHIGLDYFGRTVYIKILPVGVHMGRLESVLSLDSTAAKTKEIQEQFKGKKLVLGIDDMDIFKGISLKLIAM EHLFETYWHLKGKVVLVQIVNPARSSGKDVEEAKRETYETARRINERYGTSDYKPIVLIDRLVPRSEKTAYYAAADCCLVNAVRDGMNLVPYKYIVCRQG TRSNKAVVDSSPRTSTLVVSEFIGCSPSLSGAIRVNPWDVDAVAEAVNSALKMSETEKQLRHEKHYHYISTHDVGYWAKSFMQDLER | |||
| Full Sequence |
|---|
| Protein Sequence Length: 857 Download |
| MVSRSCANFL DLSSWDLLDF PQTPRTLPRV MTVPGIITDV DGDTTSEVTS TSGGSRERKI 60 IVANMLPLQS KRDAETGKWC FNWDEDSLQL QLRDGFSSET EFLYVGSLNV DIETNEQEEV 120 SQKLLEEFNC VATFLSQELQ EMFYLGFCKH QLWPLFHYML PMFPDHGDRF DRRLWQAYVS 180 ANKIFSDRVM EVINPEDDYV WIQDYHLMVL PTFLRKRFNR IKLGFFLHSP FPSSEIYRTL 240 PVRDEILRGL LNCDLIGFHT FDYARHFLSC CSRMLGLDYE SKRGHIGLDY FGRTVYIKIL 300 PVGVHMGRLE SVLSLDSTAA KTKEIQEQFK GKKLVLGIDD MDIFKGISLK LIAMEHLFET 360 YWHLKGKVVL VQIVNPARSS GKDVEEAKRE TYETARRINE RYGTSDYKPI VLIDRLVPRS 420 EKTAYYAAAD CCLVNAVRDG MNLVPYKYIV CRQGTRSNKA VVDSSPRTST LVVSEFIGCS 480 PSLSGAIRVN PWDVDAVAEA VNSALKMSET EKQLRHEKHY HYISTHDVGY WAKSFMQDLE 540 RACRDHYSKR CWGIGFGLGF RVLSLSPSFR KLSVEHIVPV YRKTQRRAIF LDYDGTLVPE 600 SSIVQDPSNE VVSVLKALCE DPNNTVFIVS GRGRESLSNW LSPCENLGIA AEHGYFIRWK 660 SKDEWETCYS PTDTEWRSMV EPVMRSYMEA TDGTSIEFKE SALVWHHQDA DPDFGSCQAK 720 EMLDHLESVL ANEPVVVKRG QHIVEVKPQG VSKGLAAEKV IREMVERGEP PEMVMCIGDD 780 RSDEDMFESI LSTVTNPELL VQPEVFACTV GRKPSKAKYF LDDEADVLKL LRGLGDSSSS 840 LKPSSSHTQV AFESIV* 900 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| PLN03063 | PLN03063 | 3.0e-161 | 56 | 827 | 819 | + alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional | ||
| PLN02205 | PLN02205 | 0 | 1 | 827 | 837 | + alpha,alpha-trehalose-phosphate synthase [UDP-forming] | ||
| pfam00982 | Glyco_transf_20 | 0 | 57 | 541 | 489 | + Glycosyltransferase family 20. Members of this family belong to glycosyl transferase family 20. OtsA (Trehalose-6-phosphate synthase) is homologous to regions in the subunits of yeast trehalose-6-phosphate synthase/phosphate complex. | ||
| PRK14501 | PRK14501 | 0 | 58 | 827 | 776 | + putative bifunctional trehalose-6-phosphate synthase/HAD hydrolase subfamily IIB; Provisional | ||
| cd03788 | GT1_TPS | 0 | 60 | 540 | 481 | + Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a nonreducing disaccharide present in a wide variety of organisms and may serve as a source of energy and carbon. It is characterized most notably in insect, plant, and microbial cells. Its production is often associated with a variety of stress conditions, including desiccation, dehydration, heat, cold, and oxidation. This family represents the catalytic domain of the TPS. Some members of this domain family coexist with a C-terminal trehalose phosphatase domain. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0003824 | catalytic activity |
| GO:0005992 | trehalose biosynthetic process |
| GO:0008152 | metabolic process |
| GO:0016757 | transferase activity, transferring glycosyl groups |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAC18810.1 | 0 | 31 | 856 | 1 | 826 | Strong similarity to trehalose-6-phosphate synthase homolog from A. thaliana chromosome 4 contig gb |
| GenBank | AAV65494.1 | 0 | 1 | 854 | 1 | 859 | trehalose 6-phosphate synthase [Gossypium hirsutum] |
| RefSeq | NP_173799.1 | 0 | 1 | 856 | 1 | 867 | ATTPS9; transferase, transferring glycosyl groups / trehalose-phosphatase [Arabidopsis thaliana] |
| RefSeq | NP_177186.2 | 0 | 1 | 856 | 1 | 856 | ATTPS8; alpha,alpha-trehalose-phosphate synthase (UDP-forming)/ transferase, transferring glycosyl groups / trehalose-phosphatase [Arabidopsis thaliana] |
| RefSeq | XP_002521023.1 | 0 | 1 | 856 | 1 | 861 | trehalose-6-phosphate synthase, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 1gz5_D | 0 | 113 | 541 | 44 | 452 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
| PDB | 1gz5_C | 0 | 113 | 541 | 44 | 452 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
| PDB | 1gz5_B | 0 | 113 | 541 | 44 | 452 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
| PDB | 1gz5_A | 0 | 113 | 541 | 44 | 452 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
| PDB | 2wtx_D | 0 | 113 | 541 | 45 | 453 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| trehalose biosynthesis I | TREHALOSE6PSYN-RXN | EC-2.4.1.15 | α,α-trehalose-phosphate synthase (UDP-forming) |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| HO777775 | 766 | 72 | 827 | 0 |
| HO779327 | 515 | 97 | 608 | 0 |
| HO779327 | 251 | 607 | 857 | 0 |
| HO797286 | 458 | 375 | 827 | 0 |
| HO795511 | 457 | 372 | 827 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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