| Basic Information | |
|---|---|
| Species | Arabidopsis thaliana |
| Cazyme ID | AT1G71220.2 |
| Family | GT24 |
| Protein Properties | Length: 1615 Molecular Weight: 181933 Isoelectric Point: 5.6128 |
| Chromosome | Chromosome/Scaffold: 1 Start: 26841630 End: 26851919 |
| Description | UDP-glucose glycoprotein glucosyltransferase 1 precursor, putative, expressed |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT24 | 1302 | 1549 | 0 |
| INIFSIASGHLYERFLKIMILSVLKNTNRPVKFWFIKNYLSPQFKDVIPHMAQEYNFEYELITYKWPSWLHKQKEKQRIIWAYKILFLDVIFPLSLEKVI FVDADQIIRTDMGELYDMDIKGRPLAYTPFCDNNREMDGYKFWKQGFWKEHLRGRPYHISALYVVDLVKFRETAAGDNLRVFYETLSKDPNSLSNLDQDL PNYAQHTVPIFSLPQEWLWCESWCGNATKAKARTIDLCNNPMTKEPKL | |||
| Full Sequence |
|---|
| Protein Sequence Length: 1615 Download |
| MGTTTNLRSW LYLILLFIVV VGVNAQNRRP KNVQVAVKAK WQGTPLLLEA GELISKESKQ 60 LFWEFTDAWL GSDGDDSDCK SARDCLLKIS KQASTLLAQP VASLFHFSLT LRSASPRLVL 120 YRQLADESLS SFPHGDDPSA TGCCWVDTGS SLFYDVADLQ SWLASAPAVG DAVQGPELFD 180 FDHVHFDSRA GSPVAVLYGA VGTDCFRKFH LSLAKAAKEG KVTYVVRPVL PLGCEGKTRP 240 CGAIGARDNV SLAGYGVELA LKNMEYKAMD DSAIKKGITL EDPRTEDLSQ DVRGFIFSKI 300 LDRKPELRSE VMAFRDYLLS STVSDTLDVW ELKDLGHQTA QRIVHASDPL QSMQEINQNF 360 PSVVSSLSRM KLNESIKDEI LSNQRMVPPG KALLALNGAL LNIEDIDLYM LMDLAHQELS 420 LANHFSKLKI PDGAIRKLLL TTPLPEPDSY RVDFRSVHVT YLNNLEEDDM YKRWRSNINE 480 ILMPAFPGQL RYIRKNLFHA VYVIDPATAC GLESIETLRS LYENQLPVRF GVILYSTQLI 540 KTIENNGGQI PSSDAVTNAQ VKEDLSTMVI RLFLYIKEHH GIQTAFQFLG NLNTLRTESA 600 DSSEADIEQE HVDGAFVETI LPKVKTLPQD ILLKLRQEHT LKEASEASSM FVFKLGLAKL 660 KCSFLMNGLV FDSVEEETLL NAMNEELPKI QEQVYYGQIE SHTKVLDKLL SESGLSRYNP 720 QIISGGKNKP RFVSLASSTR KGESMLNDVN YLHSPETSED VKYVTHLLAA DVATKKGMKL 780 LHEGVRYLIG GSKSARLGVL FSSSQNADPH SLLFIKFFEK TASSFSHKEK VLYFLDKLCL 840 FYEREYLLKT SVESASSQMF IDKVLELADE YGLSSKAYRS CLVESVDEEL LKRLTKVAQF 900 LSWELGLESD ANAIISNGRV IFPVDERTFL GQDLHLLESM EFNQRVKPVQ EIIEGIEWQD 960 VDPDLLTSKY FSDVFMFVSS AMATRDRSSE SARFEVLNSE YSAVLLGNEN ATIHIDAVID 1020 PLSPTGQKLA SLLQVLQKHV QTSMRIVLNP MSSLVDIPLK NYYRYVLPNT DDYSSTGFDV 1080 DGPKAFFANM PLSKTLTMNL DVPEPWLVEP VIAIHDLDNI LLENLGDTTT LQAVFEVESL 1140 VLTGHCAEKD HEAPRGLQLI LGTKNRPHLV DTLVMANLGY WQMKVSPGVW YLQLAPGRSS 1200 ELYALKGGND GSQDQSSLKR ITIDDLRGKV VHLEVVKRKG KEHEKLLVPS DGDDAVQQNK 1260 EQGSWNSNFL KWASGFVGGR QQSMKGGPDK EHEKGGRQGK TINIFSIASG HLYERFLKIM 1320 ILSVLKNTNR PVKFWFIKNY LSPQFKDVIP HMAQEYNFEY ELITYKWPSW LHKQKEKQRI 1380 IWAYKILFLD VIFPLSLEKV IFVDADQIIR TDMGELYDMD IKGRPLAYTP FCDNNREMDG 1440 YKFWKQGFWK EHLRGRPYHI SALYVVDLVK FRETAAGDNL RVFYETLSKD PNSLSNLDQD 1500 LPNYAQHTVP IFSLPQEWLW CESWCGNATK AKARTIDLCN NPMTKEPKLQ GARRIVTEWP 1560 DLDLEARKFT AKILGEDVEL NEPVAAPATD KPNPLPSNDI SEDTEQDLES KAEL* 1620 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam01501 | Glyco_transf_8 | 5.0e-5 | 1306 | 1501 | 205 | + Glycosyl transferase family 8. This family includes enzymes that transfer sugar residues to donor molecules. Members of this family are involved in lipopolysaccharide biosynthesis and glycogen synthesis. This family includes Lipopolysaccharide galactosyltransferase, lipopolysaccharide glucosyltransferase 1, and glycogenin glucosyltransferase. | ||
| cd04194 | GT8_A4GalT_like | 4.0e-15 | 1302 | 1518 | 227 | + A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface. The members of this family of glycosyltransferases catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface. The enzymes exhibit broad substrate specificities. The known functions found in this family include: Alpha-1,4-galactosyltransferase, LOS-alpha-1,3-D-galactosyltransferase, UDP-glucose:(galactosyl) LPS alpha1,2-glucosyltransferase, UDP-galactose: (glucosyl) LPS alpha1,2-galactosyltransferase, and UDP-glucose:(glucosyl) LPS alpha1,2-glucosyltransferase. Alpha-1,4-galactosyltransferase from N. meningitidis adds an alpha-galactose from UDP-Gal (the donor) to a terminal lactose (the acceptor) of the LOS structure of outer membrane. LOSs are virulence factors that enable the organism to evade the immune system of host cells. In E. coli, the three alpha-1,2-glycosyltransferases, that are involved in the synthesis of the outer core region of the LPS, are all members of this family. The three enzymes share 40 % of sequence identity, but have different sugar donor or acceptor specificities, representing the structural diversity of LPS. | ||
| cd00505 | Glyco_transf_8 | 2.0e-56 | 1302 | 1549 | 257 | + Members of glycosyltransferase family 8 (GT-8) are involved in lipopolysaccharide biosynthesis and glycogen synthesis. Members of this family are involved in lipopolysaccharide biosynthesis and glycogen synthesis. GT-8 comprises enzymes with a number of known activities: lipopolysaccharide galactosyltransferase, lipopolysaccharide glucosyltransferase 1, glycogenin glucosyltransferase, and N-acetylglucosaminyltransferase. GT-8 enzymes contains a conserved DXD motif which is essential in the coordination of a catalytic divalent cation, most commonly Mn2+. | ||
| pfam06427 | UDP-g_GGTase | 1.0e-82 | 972 | 1177 | 212 | + UDP-glucose:Glycoprotein Glucosyltransferase. The N-terminal region of this group of proteins is required for correct folding of the ER UDP-Glc: glucosyltransferase. | ||
| cd06432 | GT8_HUGT1_C_like | 3.0e-177 | 1302 | 1549 | 248 | + The C-terminal domain of HUGT1-like is highly homologous to the GT 8 family. C-terminal domain of glycoprotein glucosyltransferase (UGT). UGT is a large glycoprotein whose C-terminus contains the catalytic activity. This catalytic C-terminal domain is highly homologous to Glycosyltransferase Family 8 (GT 8) and contains the DXD motif that coordinates donor sugar binding, characteristic for Family 8 glycosyltransferases. GT 8 proteins are retaining enzymes based on the relative anomeric stereochemistry of the substrate and product in the reaction catalyzed. The non-catalytic N-terminal portion of the human UTG1 (HUGT1) has been shown to monitor the protein folding status and activate its glucosyltransferase activity. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0003980 | UDP-glucose:glycoprotein glucosyltransferase activity |
| GO:0005783 | endoplasmic reticulum |
| GO:0006486 | protein glycosylation |
| GO:0009626 | plant-type hypersensitive response |
| GO:0009751 | response to salicylic acid stimulus |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAG51883.1 | 0 | 1 | 1614 | 1 | 1674 | AC016162_4 putative UDP-glucose:glycoprotein glucosyltransferase; 101200-91134 [Arabidopsis thaliana] |
| DDBJ | BAD28382.1 | 0 | 28 | 1592 | 35 | 1614 | putative UDP-glucose:glycoprotein glucosyltransferase [Oryza sativa Japonica Group] |
| RefSeq | NP_177278.3 | 0 | 1 | 1614 | 1 | 1613 | EBS1 (EMS-mutagenized bri1 suppressor 1); UDP-glucose:glycoprotein glucosyltransferase/ transferase, transferring glycosyl groups / transferase, transferring hexosyl groups [Arabidopsis thaliana] |
| RefSeq | XP_002268972.1 | 0 | 1 | 1614 | 1 | 1611 | PREDICTED: similar to EBS1 (EMS-MUTAGENIZED BRI1 SUPPRESSOR 1); UDP-glucose:glycoprotein glucosyltransferase/ transferase, transferring glycosyl groups / transferase, transferring hexosyl groups [Vitis vinifera] |
| RefSeq | XP_002529534.1 | 0 | 1 | 1499 | 1 | 1499 | UDP-glucose glycoprotein:glucosyltransferase, putative [Ricinus communis] |
