| Basic Information | |
|---|---|
| Species | Arabidopsis thaliana |
| Cazyme ID | AT2G04560.1 |
| Family | GT19 |
| Protein Properties | Length: 461 Molecular Weight: 51464.9 Isoelectric Point: 9.1443 |
| Chromosome | Chromosome/Scaffold: 2 Start: 1590306 End: 1592667 |
| Description | lipid-A-disaccharide synthase family protein, expressed |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| GT19 | 42 | 421 | 0 |
| VFIVSGEVSGDNIGSRLMSSLKKLSPLPIRFNGVGGSLMCKKGLNSLFPMEDLAVMGVWELLPHLYKFRVKLKETIDAAVKFKPHVVVTVDSKGFSFRLL KELRARYKQQRLENCSVHFHYVAPSFWAWKGGESRLGGLSEFVDHLFCILPNEERVCREHGVEATFVGHPVLEDASEFDLVRRCKPQELKLEGLSFSEHS IPSDSTVISVLPGSRLQEVERMLPIFSKAMKLLKDPFPKLVTLIHVASNNQVDHYIGESFSEWPVPAILVPSGSTQLKYDAFGASQAALCTSGTVAVELQ LAHLPSLVAYRAHFLTELLIRYKAKIPYISLPNILLDSPIIPEALFQACNPSNLASILERLLLDEKMRERQVVGAEKLIQ | |||
| Full Sequence |
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| Protein Sequence Length: 461 Download |
| MMFQITKSKL RFPLSTFTKR YSSFQAAKSV IDKAAIDGEL RVFIVSGEVS GDNIGSRLMS 60 SLKKLSPLPI RFNGVGGSLM CKKGLNSLFP MEDLAVMGVW ELLPHLYKFR VKLKETIDAA 120 VKFKPHVVVT VDSKGFSFRL LKELRARYKQ QRLENCSVHF HYVAPSFWAW KGGESRLGGL 180 SEFVDHLFCI LPNEERVCRE HGVEATFVGH PVLEDASEFD LVRRCKPQEL KLEGLSFSEH 240 SIPSDSTVIS VLPGSRLQEV ERMLPIFSKA MKLLKDPFPK LVTLIHVASN NQVDHYIGES 300 FSEWPVPAIL VPSGSTQLKY DAFGASQAAL CTSGTVAVEL QLAHLPSLVA YRAHFLTELL 360 IRYKAKIPYI SLPNILLDSP IIPEALFQAC NPSNLASILE RLLLDEKMRE RQVVGAEKLI 420 QLLHPSESRM GNSIHCTGLE SHRYTPSILA ASTILSYARR * |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| PRK01021 | lpxB | 4.0e-41 | 43 | 430 | 397 | + lipid-A-disaccharide synthase; Reviewed | ||
| TIGR00215 | lpxB | 4.0e-48 | 42 | 405 | 368 | + lipid-A-disaccharide synthase. Lipid-A precursor biosynthesis producing lipid A disaccharide in a condensation reaction. transcribed as part of an operon including lpxA [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides]. | ||
| pfam02684 | LpxB | 6.0e-72 | 42 | 430 | 390 | + Lipid-A-disaccharide synthetase. This is a family of lipid-A-disaccharide synthetases, EC:2.4.2.128. These enzymes catalyze the reaction: UDP-2,3-bis(3-hydroxytetradecanoyl) glucosamine + 2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate <=> UDP + 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6 -beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate. These enzymes catalyze the fist disaccharide step in the synthesis of lipid-A-disaccharide. | ||
| PRK00025 | lpxB | 2.0e-93 | 40 | 425 | 388 | + lipid-A-disaccharide synthase; Reviewed | ||
| COG0763 | LpxB | 1.0e-98 | 40 | 424 | 387 | + Lipid A disaccharide synthetase [Cell envelope biogenesis, outer membrane] | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0005575 | cellular_component |
| GO:0008915 | lipid-A-disaccharide synthase activity |
| GO:0009245 | lipid A biosynthetic process |
| GO:0016757 | transferase activity, transferring glycosyl groups |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CBI28885.1 | 0 | 34 | 459 | 2 | 430 | unnamed protein product [Vitis vinifera] |
| GenBank | EEC71491.1 | 0 | 30 | 455 | 34 | 463 | hypothetical protein OsI_03760 [Oryza sativa Indica Group] |
| RefSeq | NP_178535.2 | 0 | 1 | 460 | 1 | 455 | transferase, transferring glycosyl groups [Arabidopsis thaliana] |
| RefSeq | XP_002458499.1 | 0 | 30 | 459 | 9 | 443 | hypothetical protein SORBIDRAFT_03g034785 [Sorghum bicolor] |
| RefSeq | XP_002528957.1 | 0 | 19 | 459 | 26 | 468 | Lipid-A-disaccharide synthase, putative [Ricinus communis] |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| lipid IVA biosynthesis | LIPIDADISACCHARIDESYNTH-RXN | EC-2.4.1.182 | lipid-A-disaccharide synthase |
| Hydropathy |
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| EST Download unfiltered results here | ||||
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| Hit | Length | Start | End | EValue |
| FY429474 | 269 | 2 | 268 | 0 |
| DK475923 | 226 | 2 | 226 | 0 |
| EV196281 | 236 | 2 | 236 | 0 |
| DK547548 | 209 | 254 | 461 | 0 |
| EY717263 | 261 | 78 | 335 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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| Phylogeny |
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