| Basic Information | |
|---|---|
| Species | Arabidopsis thaliana |
| Cazyme ID | AT2G18700.1 |
| Family | GT20 |
| Protein Properties | Length: 863 Molecular Weight: 98275.2 Isoelectric Point: 7.3662 |
| Chromosome | Chromosome/Scaffold: 2 Start: 8109043 End: 8112010 |
| Description | trehalose-6-phosphate synthase, putative, expressed |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT20 | 50 | 538 | 0 |
| PKRIVVSNQLPLRAHRDISSNKWCFEFDNDSLYLQLKDGFPPETEVVYVGSLNADVLPSEQEDVSQFLLEKFQCVPTFLPSDLLNKYYHGFCKHYLWPIF HYLLPMTQAQGSLFDRSNWRAYTTVNKIFADKIFEVLNPDDDYVWIHDYHLMILPTFLRNRFHRIKLGIFLHSPFPSSEIYRTLPVRDEILKGFLNCDLV GFHTFDYARHFLSCCSRMLGLDYESKRGYIGLEYFGRTVSIKILPVGIHMGQIESIKASEKTAEKVKRLRERFKGNIVMLGVDDLDMFKGISLKFWAMGQ LLEQNEELRGKVVLVQITNPARSSGKDVQDVEKQINLIADEINSKFGRPGGYKPIVFINGPVSTLDKVAYYAISECVVVNAVRDGMNLVPYKYTVTRQGS PALDAALGFGEDDVRKSVIIVSEFIGCSPSLSGAIRVNPWNIDAVTNAMSSAMTMSDKEKNLRHQKHHKYISSHNVAYWARSYDQDLQR | |||
| Full Sequence |
|---|
| Protein Sequence Length: 863 Download |
| MSPESWKDQL SLVSADDYRI MGRNRIPNAV TKLSGLETDD PNGGAWVTKP KRIVVSNQLP 60 LRAHRDISSN KWCFEFDNDS LYLQLKDGFP PETEVVYVGS LNADVLPSEQ EDVSQFLLEK 120 FQCVPTFLPS DLLNKYYHGF CKHYLWPIFH YLLPMTQAQG SLFDRSNWRA YTTVNKIFAD 180 KIFEVLNPDD DYVWIHDYHL MILPTFLRNR FHRIKLGIFL HSPFPSSEIY RTLPVRDEIL 240 KGFLNCDLVG FHTFDYARHF LSCCSRMLGL DYESKRGYIG LEYFGRTVSI KILPVGIHMG 300 QIESIKASEK TAEKVKRLRE RFKGNIVMLG VDDLDMFKGI SLKFWAMGQL LEQNEELRGK 360 VVLVQITNPA RSSGKDVQDV EKQINLIADE INSKFGRPGG YKPIVFINGP VSTLDKVAYY 420 AISECVVVNA VRDGMNLVPY KYTVTRQGSP ALDAALGFGE DDVRKSVIIV SEFIGCSPSL 480 SGAIRVNPWN IDAVTNAMSS AMTMSDKEKN LRHQKHHKYI SSHNVAYWAR SYDQDLQRAC 540 KDHYNKRFWG VGFGLFFKVV ALDPNFRRLC GETIVPAYRR SSSRLILLDY DGTMMDQDTL 600 DKRPSDDLIS LLNRLCDDPS NLVFIVSGRG KDPLSKWFDS CPNLGISAEH GYFTRWNSNS 660 PWETSELPAD LSWKKIAKPV MNHYMEATDG SFIEEKESAM VWHHQEADHS FGSWQAKELL 720 DHLESVLTNE PVVVKRGQHI VEVKPQGVSK GKVVEHLIAT MRNTKGKRPD FLLCIGDDRS 780 DEDMFDSIVK HQDVSSIGLE EVFACTVGQK PSKAKYYLDD TPSVIKMLEW LASASDGSKH 840 EQQKKQSKFT FQQPMGQCRK KA* 900 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| PLN03063 | PLN03063 | 4.0e-160 | 49 | 836 | 824 | + alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional | ||
| PLN02205 | PLN02205 | 0 | 1 | 836 | 853 | + alpha,alpha-trehalose-phosphate synthase [UDP-forming] | ||
| pfam00982 | Glyco_transf_20 | 0 | 50 | 538 | 493 | + Glycosyltransferase family 20. Members of this family belong to glycosyl transferase family 20. OtsA (Trehalose-6-phosphate synthase) is homologous to regions in the subunits of yeast trehalose-6-phosphate synthase/phosphate complex. | ||
| PRK14501 | PRK14501 | 0 | 53 | 834 | 788 | + putative bifunctional trehalose-6-phosphate synthase/HAD hydrolase subfamily IIB; Provisional | ||
| cd03788 | GT1_TPS | 0 | 51 | 537 | 487 | + Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a nonreducing disaccharide present in a wide variety of organisms and may serve as a source of energy and carbon. It is characterized most notably in insect, plant, and microbial cells. Its production is often associated with a variety of stress conditions, including desiccation, dehydration, heat, cold, and oxidation. This family represents the catalytic domain of the TPS. Some members of this domain family coexist with a C-terminal trehalose phosphatase domain. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0003824 | catalytic activity |
| GO:0005739 | mitochondrion |
| GO:0005992 | trehalose biosynthetic process |
| GO:0008152 | metabolic process |
| GO:0016757 | transferase activity, transferring glycosyl groups |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| DDBJ | BAF98176.1 | 0 | 10 | 835 | 7 | 846 | trehalose-6-phosphate synthase [Solanum lycopersicum] |
| RefSeq | NP_179460.1 | 0 | 1 | 862 | 1 | 862 | ATTPS11; transferase, transferring glycosyl groups [Arabidopsis thaliana] |
| RefSeq | XP_002308438.1 | 0 | 1 | 840 | 1 | 845 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002325087.1 | 0 | 12 | 839 | 1 | 826 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002533178.1 | 0 | 51 | 835 | 8 | 792 | trehalose-6-phosphate synthase, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 1gz5_D | 0 | 133 | 538 | 72 | 452 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
| PDB | 1gz5_C | 0 | 133 | 538 | 72 | 452 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
| PDB | 1gz5_B | 0 | 133 | 538 | 72 | 452 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
| PDB | 1gz5_A | 0 | 133 | 538 | 72 | 452 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
| PDB | 2wtx_D | 0 | 133 | 538 | 73 | 453 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
| Hydropathy |
|---|
 |
| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| HO777775 | 780 | 61 | 836 | 0 |
| HO779327 | 514 | 92 | 605 | 0 |
| HO779327 | 236 | 601 | 835 | 0 |
| HO797286 | 472 | 367 | 838 | 0 |
| HO795511 | 475 | 365 | 838 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
|---|
 |
