| Basic Information | |
|---|---|
| Species | Arabidopsis thaliana |
| Cazyme ID | AT2G19880.2 |
| Family | GT21 |
| Protein Properties | Length: 521 Molecular Weight: 58770.2 Isoelectric Point: 9.0425 |
| Chromosome | Chromosome/Scaffold: 2 Start: 8581460 End: 8585478 |
| Description | expressed protein |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT21 | 84 | 314 | 1e-34 |
| PRVSVVMPLKGFGEHNLHNWRSQITSLYGGPLEFLFVVESTEDPAYHAVSRLLSMYQDHVEAKVVVAGLSTTCSQKIHNQLIGVEKMHKDTKYVLFLDDD VRLHPGTIGALTTEMEKNPEIFIQTGYPLDLPSGTLGSYCIYEYHMPCSMGFATGGRTFFLWGGCMMMHADDFRQDRYGVVSGLRDGGYSDDMTLASLAG AHKRLITSPPVAVFPHPLASDLSFGRYWNYL | |||
| Full Sequence |
|---|
| Protein Sequence Length: 521 Download |
| MSTLDSIDAI LFSLSRAFTS PFAVFVQIQG CTICLLLALG WLLAEYVRNR EVKRIKNSIK 60 AGNSLAFLYQ DINELEHSRQ VKLPRVSVVM PLKGFGEHNL HNWRSQITSL YGGPLEFLFV 120 VESTEDPAYH AVSRLLSMYQ DHVEAKVVVA GLSTTCSQKI HNQLIGVEKM HKDTKYVLFL 180 DDDVRLHPGT IGALTTEMEK NPEIFIQTGY PLDLPSGTLG SYCIYEYHMP CSMGFATGGR 240 TFFLWGGCMM MHADDFRQDR YGVVSGLRDG GYSDDMTLAS LAGAHKRLIT SPPVAVFPHP 300 LASDLSFGRY WNYLRKQTFV LESYISKVNW IMNKALFAVH CYLSWGFVAP YVMAIIHITS 360 ALRIYIKGYH QLEDTTSASG GMMLVITLAI CTFIELLSMW NLTRREVQLC NMLSPEAPRL 420 SLATYNWGLV FVAMLVDNFL YPISAFRSHF SQSINWSGIR YHLKDGKIFK IERRKDMGPT 480 KTDLGGKHLY GKKGAPQKAS FLSSLGRNLA HWRQPKKFDV * 540 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| cd04186 | GT_2_like_c | 3.0e-5 | 161 | 258 | 98 | + Subfamily of Glycosyltransferase Family GT2 of unknown function. GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families. | ||
| pfam13641 | Glyco_tranf_2_3 | 2.0e-6 | 84 | 257 | 181 | + Glycosyltransferase like family 2. Members of this family of prokaryotic proteins include putative glucosyltransferase, which are involved in bacterial capsule biosynthesis. | ||
| COG1215 | COG1215 | 9.0e-9 | 81 | 476 | 413 | + Glycosyltransferases, probably involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane] | ||
| cd02520 | Glucosylceramide_synthase | 4.0e-9 | 84 | 204 | 124 | + Glucosylceramide synthase catalyzes the first glycosylation step of glycosphingolipid synthesis. UDP-glucose:N-acylsphingosine D-glucosyltransferase (glucosylceramide synthase or ceramide glucosyltransferase) catalyzes the first glycosylation step of glycosphingolipid synthesis. Its product, glucosylceramide, serves as the core of more than 300 glycosphingolipids (GSL). GSLs are a group of membrane components that have the lipid portion embedded in the outer plasma membrane leaflet and the sugar chains extended to the outer environment. Several lines of evidence suggest the importance of GSLs in various cellular processes such as differentiation, adhesion, proliferation, and cell-cell recognition. In pathogenic fungus Cryptococcus neoformans, glucosylceramide serves as an antigen that elicits an antibody response in patients and it is essential for fungal growth in host extracellular environment. | ||
| pfam13506 | Glyco_transf_21 | 9.0e-12 | 142 | 315 | 178 | + Glycosyl transferase family 21. This is a family of ceramide beta-glucosyltransferases - EC:2.4.1.80. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0008120 | ceramide glucosyltransferase activity |
| GO:0008150 | biological_process |
| GO:0012505 | endomembrane system |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAK73021.1 | 0 | 2 | 520 | 3 | 520 | AF367245_1 ceramide glucosyltransferase [Gossypium arboreum] |
| GenBank | AAL11579.1 | 0 | 1 | 520 | 1 | 519 | AF424585_1 At2g19880/F6F22.9 [Arabidopsis thaliana] |
| GenBank | ABK95617.1 | 0 | 5 | 520 | 3 | 517 | unknown [Populus trichocarpa] |
| RefSeq | NP_565460.1 | 0 | 1 | 520 | 1 | 519 | ceramide glucosyltransferase, putative [Arabidopsis thaliana] |
| RefSeq | XP_002514215.1 | 0 | 2 | 519 | 5 | 521 | ceramide glucosyltransferase, putative [Ricinus communis] |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| sphingolipid biosynthesis (plants) | RXN-7793 | EC-2.4.1.80 | ceramide glucosyltransferase |
