| Basic Information | |
|---|---|
| Species | Arabidopsis thaliana |
| Cazyme ID | AT2G34810.1 |
| Family | AA7 |
| Protein Properties | Length: 541 Molecular Weight: 61307 Isoelectric Point: 10.1157 |
| Chromosome | Chromosome/Scaffold: 2 Start: 14685256 End: 14687062 |
| Description | berberine and berberine like domain containing protein, expressed |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| AA7 | 72 | 536 | 0 |
| NLRFASVSTRKPEVIVAAVTETHIRATISCCKLLNLELRIRSGGHDYEGFSYTSPVPFVILDMYNFNKIDINMKDETVWIQSGASLGQLYYNIASKSKVH AFPAGVCPKVGAGGHFSGGGFGNLMRKYGLSIDHIIDAQIMDANGKVYRNRQAMGEDVFWAIRGGGGGSYGVILAWKIKLVRVPEKVTVFKLERTVREGA VDLVHKWQQVAPVIDRDLFIRLEIKPINRKISKGKTIKVSFIGMFLGLPERLLNITKQSFPELHLTKEDCMVKKWIESSVFWANYPEKAPIELLLKRVST NEYYWKRTSDFVQAPISKQGLAKIFQTMIDHSPLPRRVWMQWNPWGGKMAEIASDATAFVHRGGNVFMIEHFMNWYRPGDELEEKFLAIARSFKEAMAPF VSKNPREAFFNYRDVDIGITTPGYNATYEGAKVYGDSYFKGNYLRLVKIKARFDRTNFFRSQQGI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 541 Download |
| MKFWSRPLTF LIIIIYLIIQ QVNSSPPSLS IPEHFLRCLD TQPSDHGSPN SRTAVIPTNS 60 SFSTNLMNGV RNLRFASVST RKPEVIVAAV TETHIRATIS CCKLLNLELR IRSGGHDYEG 120 FSYTSPVPFV ILDMYNFNKI DINMKDETVW IQSGASLGQL YYNIASKSKV HAFPAGVCPK 180 VGAGGHFSGG GFGNLMRKYG LSIDHIIDAQ IMDANGKVYR NRQAMGEDVF WAIRGGGGGS 240 YGVILAWKIK LVRVPEKVTV FKLERTVREG AVDLVHKWQQ VAPVIDRDLF IRLEIKPINR 300 KISKGKTIKV SFIGMFLGLP ERLLNITKQS FPELHLTKED CMVKKWIESS VFWANYPEKA 360 PIELLLKRVS TNEYYWKRTS DFVQAPISKQ GLAKIFQTMI DHSPLPRRVW MQWNPWGGKM 420 AEIASDATAF VHRGGNVFMI EHFMNWYRPG DELEEKFLAI ARSFKEAMAP FVSKNPREAF 480 FNYRDVDIGI TTPGYNATYE GAKVYGDSYF KGNYLRLVKI KARFDRTNFF RSQQGIPVLA 540 * 600 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| PLN02805 | PLN02805 | 0.007 | 83 | 314 | 248 | + D-lactate dehydrogenase [cytochrome] | ||
| COG0277 | GlcD | 4.0e-13 | 76 | 539 | 475 | + FAD/FMN-containing dehydrogenases [Energy production and conversion] | ||
| pfam08031 | BBE | 2.0e-13 | 479 | 537 | 59 | + Berberine and berberine like. This domain is found in the berberine bridge and berberine bridge- like enzymes which are involved in the biosynthesis of numerous isoquinoline alkaloids. They catalyze the transformation of the N-methyl group of (S)-reticuline into the C-8 berberine bridge carbon of (S)-scoulerine. | ||
| pfam01565 | FAD_binding_4 | 1.0e-17 | 83 | 220 | 139 | + FAD binding domain. This family consists of various enzymes that use FAD as a co-factor, most of the enzymes are similar to oxygen oxidoreductase. One of the enzymes Vanillyl-alcohol oxidase (VAO) has a solved structure, the alignment includes the FAD binding site, called the PP-loop, between residues 99-110. The FAD molecule is covalently bound in the known structure, however the residue that links to the FAD is not in the alignment. VAO catalyzes the oxidation of a wide variety of substrates, ranging form aromatic amines to 4-alkylphenols. Other members of this family include D-lactate dehydrogenase, this enzyme catalyzes the conversion of D-lactate to pyruvate using FAD as a co-factor; mitomycin radical oxidase, this enzyme oxidises the reduced form of mitomycins and is involved in mitomycin resistance. This family includes MurB an UDP-N-acetylenolpyruvoylglucosamine reductase enzyme EC:1.1.1.158. This enzyme is involved in the biosynthesis of peptidoglycan. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0003824 | catalytic activity |
| GO:0008762 | UDP-N-acetylmuramate dehydrogenase activity |
| GO:0009055 | electron carrier activity |
| GO:0009611 | response to wounding |
| GO:0009753 | response to jasmonic acid stimulus |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | NP_174359.1 | 0 | 24 | 538 | 18 | 525 | FAD-binding domain-containing protein [Arabidopsis thaliana] |
| RefSeq | NP_181027.1 | 0 | 1 | 540 | 1 | 540 | FAD-binding domain-containing protein [Arabidopsis thaliana] |
| RefSeq | XP_002317074.1 | 0 | 15 | 537 | 1 | 513 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002317086.1 | 0 | 7 | 538 | 4 | 525 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002523155.1 | 0 | 33 | 537 | 27 | 522 | Reticuline oxidase precursor, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3vte_A | 0 | 33 | 539 | 5 | 513 | A Chain A, Crystal Structure Of Tetrahydrocannabinolic Acid Synthase From Cannabis Sativa |
| PDB | 4dns_B | 0 | 25 | 539 | 1 | 496 | A Chain A, Crystal Structure Of Bermuda Grass Isoallergen Bg60 Provides Insight Into The Various Cross-Allergenicity Of The Pollen Group 4 Allergens |
| PDB | 4dns_A | 0 | 25 | 539 | 1 | 496 | A Chain A, Crystal Structure Of Bermuda Grass Isoallergen Bg60 Provides Insight Into The Various Cross-Allergenicity Of The Pollen Group 4 Allergens |
| PDB | 3tsj_B | 0 | 27 | 539 | 3 | 496 | A Chain A, Crystal Structure Of Bermuda Grass Isoallergen Bg60 Provides Insight Into The Various Cross-Allergenicity Of The Pollen Group 4 Allergens |
| PDB | 3tsj_A | 0 | 27 | 539 | 3 | 496 | A Chain A, Crystal Structure Of Bermuda Grass Isoallergen Bg60 Provides Insight Into The Various Cross-Allergenicity Of The Pollen Group 4 Allergens |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| cannabinoid biosynthesis | RXN-7854 | EC-1.21.3 | tetrahydrocannabinolic acid synthase |
