| Basic Information | |
|---|---|
| Species | Arabidopsis thaliana |
| Cazyme ID | AT2G35100.1 |
| Family | GT47 |
| Protein Properties | Length: 448 Molecular Weight: 50782.3 Isoelectric Point: 9.3241 |
| Chromosome | Chromosome/Scaffold: 2 Start: 14793651 End: 14795629 |
| Description | exostosin family domain containing protein, expressed |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 59 | 371 | 0 |
| RVRVYMYNLPKRFTYGLIEQHSIARGGIKKPVGDVTTLKYPGHQHMHEWYLFSDLNQPEVDRSGSPIVRVSDPADADLFYVPVFSSLSLIVNAGRPVEAG SGYSDEKMQEGLVEWLEGQEWWRRNAGRDHVIPAGDPNALYRILDRVKNAVLLVSDFGRLRPDQGSFVKDVVIPYSHRVNLFNGEIGVEDRNTLLFFMGN RYRKDGGKVRDLLFQVLEKEDDVTIKHGTQSRENRRAATKGMHTSKFCLNPAGDTPSACRLFDSIVSLCVPLIVSDSIELPFEDVIDYRKFSIFVEANAA LQPGFLVQMLRKI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 448 Download |
| MARKSSLLKR AAIAVVSVIA IYVILNASVS RSLPSSSDLP RQLIREDDDD EGRAPIQPRV 60 RVYMYNLPKR FTYGLIEQHS IARGGIKKPV GDVTTLKYPG HQHMHEWYLF SDLNQPEVDR 120 SGSPIVRVSD PADADLFYVP VFSSLSLIVN AGRPVEAGSG YSDEKMQEGL VEWLEGQEWW 180 RRNAGRDHVI PAGDPNALYR ILDRVKNAVL LVSDFGRLRP DQGSFVKDVV IPYSHRVNLF 240 NGEIGVEDRN TLLFFMGNRY RKDGGKVRDL LFQVLEKEDD VTIKHGTQSR ENRRAATKGM 300 HTSKFCLNPA GDTPSACRLF DSIVSLCVPL IVSDSIELPF EDVIDYRKFS IFVEANAALQ 360 PGFLVQMLRK IKTKKILEYQ REMKSVRRYF DYDNPNGAVK EIWRQVSHKL PLIKLMSNRD 420 RRLVLRNLTE PNCSCLCTNQ TGLITSI* 480 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 3.0e-81 | 56 | 371 | 327 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0003824 | catalytic activity |
| GO:0012505 | endomembrane system |
| GO:0016020 | membrane |
| GO:0016757 | transferase activity, transferring glycosyl groups |
| GO:0045489 | pectin biosynthetic process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAC61825.1 | 0 | 1 | 385 | 1 | 385 | unknown protein [Arabidopsis thaliana] |
| RefSeq | NP_199306.1 | 0 | 9 | 447 | 14 | 443 | ARAD2 (ARABINAN DEFICIENT 2); catalytic [Arabidopsis thaliana] |
| RefSeq | NP_850241.1 | 0 | 1 | 447 | 1 | 447 | ARAD1 (ARABINAN DEFICIENT 1); catalytic/ transferase, transferring glycosyl groups [Arabidopsis thaliana] |
| RefSeq | XP_002322391.1 | 0 | 1 | 447 | 1 | 457 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002523645.1 | 0 | 1 | 447 | 1 | 452 | catalytic, putative [Ricinus communis] |
