y
Basic Information | |
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Species | Arabidopsis thaliana |
Cazyme ID | AT2G40190.1 |
Family | GT4 |
Protein Properties | Length: 464 Molecular Weight: 52572.6 Isoelectric Point: 7.9664 |
Chromosome | Chromosome/Scaffold: 2 Start: 16785194 End: 16787530 |
Description | glycosyl transferase, group 1 domain containing protein, expressed |
View CDS |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT4 | 266 | 426 | 2.8e-24 |
SDPPKIISVAQFRPEKAHMLQLEAFSLALEKLDADVPRPKLQFVGSCRNNSDEERLQKLKDRAVELKVDGDVQFYKNAMYRELVELLGNAVAGLHGMIDE HFGISVVEYMAAGAIPIAHNSAGPKMDIVLEEDGQKTGFLAETVEEYAEAILEIVKMNETE |
Full Sequence |
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Protein Sequence Length: 464 Download |
MAIYFILYTL LTIIFAVSLS LFLSVINARK SRKRAVGFFH PYTNDGGGGE RVLWCAVKAI 60 QEENPDLDCV IFTGDHDSSS DSLARRAVDR FGVHLQSPPK VIHLNKRKWI EESTYPHFTM 120 IGQSLGSVYL AWEALRMFTP LYFLDTSGYA FTYPLARIFG CKVVCYTHYP TISLDMISRV 180 RQRNSMYNND ASIAKSNWLS TCKLVYYRAF SWMYGMVGSC THLAMVNSSW TKSHIEVLWR 240 IPERITRVYP PCDTSGLQAF PLERSSDPPK IISVAQFRPE KAHMLQLEAF SLALEKLDAD 300 VPRPKLQFVG SCRNNSDEER LQKLKDRAVE LKVDGDVQFY KNAMYRELVE LLGNAVAGLH 360 GMIDEHFGIS VVEYMAAGAI PIAHNSAGPK MDIVLEEDGQ KTGFLAETVE EYAEAILEIV 420 KMNETERLKM AESARKRAAR FSEQRFCEDF KTAIRPIFTG PLK* 480 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
COG0438 | RfaG | 2.0e-22 | 203 | 455 | 257 | + Glycosyltransferase [Cell envelope biogenesis, outer membrane] | ||
pfam00534 | Glycos_transf_1 | 5.0e-25 | 267 | 437 | 173 | + Glycosyl transferases group 1. Mutations in this domain of human PIGA lead to disease (Paroxysmal Nocturnal haemoglobinuria). Members of this family transfer activated sugars to a variety of substrates, including glycogen, Fructose-6-phosphate and lipopolysaccharides. Members of this family transfer UDP, ADP, GDP or CMP linked sugars. The eukaryotic glycogen synthases may be distant members of this family. | ||
cd03805 | GT1_ALG2_like | 3.0e-26 | 154 | 450 | 314 | + This family is most closely related to the GT1 family of glycosyltransferases. ALG2, a 1,3-mannosyltransferase, in yeast catalyzes the mannosylation of Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate. A deficiency of this enzyme causes an abnormal accumulation of Man1GlcNAc2-PP-dolichol and Man2GlcNAc2-PP-dolichol, which is associated with a type of congenital disorders of glycosylation (CDG), designated CDG-Ii, in humans. | ||
PLN02949 | PLN02949 | 0 | 17 | 463 | 447 | + transferase, transferring glycosyl groups | ||
cd03806 | GT1_ALG11_like | 0 | 34 | 446 | 416 | + This family is most closely related to the GT1 family of glycosyltransferases. ALG11 in yeast is involved in adding the final 1,2-linked Man to the Man5GlcNAc2-PP-Dol synthesized on the cytosolic face of the ER. The deletion analysis of ALG11 was shown to block the early steps of core biosynthesis that takes place on the cytoplasmic face of the ER and lead to a defect in the assembly of lipid-linked oligosaccharides. |
Gene Ontology | |
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GO Term | Description |
GO:0005789 | endoplasmic reticulum membrane |
GO:0006496 | protein amino acid terminal N-glycosylation |
GO:0006970 | response to osmotic stress |
GO:0009058 | biosynthetic process |
GO:0009737 | response to abscisic acid stimulus |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAD25934.1 | 0 | 27 | 463 | 27 | 474 | AF085279_7 hypothetical protein [Arabidopsis thaliana] |
GenBank | AAY86782.1 | 0 | 1 | 463 | 1 | 463 | glycosyl transferase family 1 protein [Noccaea caerulescens] |
RefSeq | NP_181548.2 | 0 | 27 | 463 | 27 | 463 | glycosyl transferase family 1 protein [Arabidopsis thaliana] |
RefSeq | XP_002318120.1 | 0 | 25 | 459 | 28 | 462 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002528312.1 | 0 | 25 | 457 | 27 | 459 | glycosyl transferase, putative [Ricinus communis] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 2f9f_A | 0.00004 | 272 | 441 | 27 | 177 | A Chain A, Crystal Structure Of The Putative Mannosyl Transferase (Wbaz-1)from Archaeoglobus Fulgidus, Northeast Structural Genomics Target Gr29a |
PDB | 3fro_C | 0.00005 | 327 | 453 | 303 | 426 | A Chain A, Crystal Structure Of Pyrococcus Abyssi Glycogen Synthase With Open And Closed Conformations |
PDB | 3fro_B | 0.00005 | 327 | 453 | 303 | 426 | A Chain A, Crystal Structure Of Pyrococcus Abyssi Glycogen Synthase With Open And Closed Conformations |
PDB | 3fro_A | 0.00005 | 327 | 453 | 303 | 426 | A Chain A, Crystal Structure Of Pyrococcus Abyssi Glycogen Synthase With Open And Closed Conformations |
PDB | 2bis_C | 0.00006 | 327 | 453 | 304 | 427 | A Chain A, Structure Of Glycogen Synthase From Pyrococcus Abyssi |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
dolichyl-diphosphooligosaccharide biosynthesis | RXN-5464 | EC-2.4.1.131 | GDP-Man:Man3GlcNAc2-PP-Dol α-1,2-mannosyltransferase |