| Basic Information | |
|---|---|
| Species | Arabidopsis thaliana |
| Cazyme ID | AT2G43570.1 |
| Family | GH19 |
| Protein Properties | Length: 278 Molecular Weight: 29775.4 Isoelectric Point: 5.8402 |
| Chromosome | Chromosome/Scaffold: 2 Start: 18076224 End: 18077463 |
| Description | CHIT1 - Chitinase family protein precursor, expressed |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GH19 | 78 | 277 | 0 |
| EGTVTPDFFNSILNQRGDCPGKGFYTHDTFMAAANSYPSFGASISKREIAAFFAHVAQETGFMCYIEEIDGPAKAASGEYCDTEKPEFPCAQGKGYYGRG AIQLSWNYNYGLCGKALDENLLASPEKVAQDQVLAFKTAFWFWTTNVRTSFKSGFGATIRAVNSRECSGGDSTAKAANRIKYFQDYCGKLGVAPGDNLTC | |||
| Full Sequence |
|---|
| Protein Sequence Length: 278 Download |
| MAKPTSRNDR FALFFITLIF LILTVSKPVA SQNCGCASDF CCSKYGYCGT TDEFCGEGCQ 60 AGPCRSSGGG GDPAVSLEGT VTPDFFNSIL NQRGDCPGKG FYTHDTFMAA ANSYPSFGAS 120 ISKREIAAFF AHVAQETGFM CYIEEIDGPA KAASGEYCDT EKPEFPCAQG KGYYGRGAIQ 180 LSWNYNYGLC GKALDENLLA SPEKVAQDQV LAFKTAFWFW TTNVRTSFKS GFGATIRAVN 240 SRECSGGDST AKAANRIKYF QDYCGKLGVA PGDNLTC* 300 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| smart00270 | ChtBD1 | 1.0e-6 | 36 | 62 | 27 | + Chitin binding domain. | ||
| COG3179 | COG3179 | 1.0e-6 | 110 | 222 | 146 | + Predicted chitinase [General function prediction only] | ||
| cd00442 | lysozyme_like | 2.0e-8 | 165 | 249 | 85 | + lysozyme_like domain. This contains several members including Soluble Lytic Transglycosylases (SLT), Goose Egg-White Lysozymes (GEWL), Hen Egg-White Lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, and chitosanases. All the members are involved in the hydrolysis of beta-1,4- linked polysaccharides. | ||
| pfam00182 | Glyco_hydro_19 | 1.0e-74 | 81 | 277 | 236 | + Chitinase class I. | ||
| cd00325 | chitinase_glyco_hydro_19 | 1.0e-87 | 81 | 277 | 235 | + Glycoside hydrolase family 19 chitinase domain. Chitinases are enzymes that catalyze the hydrolysis of the beta-1,4-N-acetyl-D-glucosamine linkages in chitin polymers. Family 19 chitinases are found primarily in plants (classes I, III, and IV), but some are found in bacteria. Class I and II chitinases are similar in their catalytic domains. Class I chitinases have an N-terminal cysteine-rich, chitin-binding domain which is separated from the catalytic domain by a proline and glycine-rich hinge region. Class II chitinases lack both the chitin-binding domain and the hinge region. Class IV chitinases are similar to class I chitinases but they are smaller in size due to certain deletions. Despite any significant sequence homology with lysozymes, structural analysis reveals that family 19 chitinases, together with family 46 chitosanases, are similar to several lysozymes including those from T4-phage and from goose. The structures reveal that the different enzyme groups arose from a common ancestor glycohydrolase antecedent to the procaryotic/eucaryotic divergence. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004568 | chitinase activity |
| GO:0005975 | carbohydrate metabolic process |
| GO:0006032 | chitin catabolic process |
| GO:0008061 | chitin binding |
| GO:0009505 | plant-type cell wall |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAB01665.1 | 0 | 15 | 277 | 1 | 266 | chitinase class IV [Brassica napus] |
| GenBank | AAK62047.1 | 0 | 2 | 277 | 4 | 282 | chitinase class 4-like protein [Brassica napus] |
| GenBank | ABQ57389.1 | 0 | 2 | 277 | 4 | 278 | class IV chitinase [Brassica juncea] |
| RefSeq | NP_181885.1 | 0 | 1 | 277 | 1 | 277 | chitinase, putative [Arabidopsis thaliana] |
| Swiss-Prot | Q06209 | 0 | 13 | 277 | 6 | 268 | CHI4_BRANA RecName: Full=Basic endochitinase CHB4; Flags: Precursor |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3hbh_A | 0 | 76 | 277 | 1 | 204 | A Chain A, Crystal Structure Of A Putative Plp-Dependent Beta-Cystathionase (Aecd, Dip1736) From Corynebacterium Diphtheriae At 1.99 A Resolution |
| PDB | 3hbe_X | 0 | 76 | 277 | 1 | 204 | A Chain A, Crystal Structure Of A Putative Plp-Dependent Beta-Cystathionase (Aecd, Dip1736) From Corynebacterium Diphtheriae At 1.99 A Resolution |
| PDB | 3hbd_A | 0 | 76 | 277 | 1 | 204 | A Chain A, Class Iv Chitinase Structure From Picea Abies At 1.8a |
| PDB | 3cql_B | 0 | 77 | 277 | 2 | 236 | A Chain A, Crystal Structure Of Gh Family 19 Chitinase From Carica Papaya |
| PDB | 3cql_A | 0 | 77 | 277 | 2 | 236 | A Chain A, Crystal Structure Of Gh Family 19 Chitinase From Carica Papaya |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| chitin degradation II | 3.2.1.14-RXN | EC-3.2.1.14 | chitinase |
| chitin degradation II | RXN-12623 | EC-3.2.1.14 | chitinase |
| chitin degradation II | RXN-12624 | EC-3.2.1.14 | chitinase |
| chitin degradation III (carnivorous plants) | 3.2.1.14-RXN | EC-3.2.1.14 | chitinase |
