| Basic Information | |
|---|---|
| Species | Arabidopsis thaliana |
| Cazyme ID | AT2G43620.1 |
| Family | GH19 |
| Protein Properties | Length: 284 Molecular Weight: 30377.7 Isoelectric Point: 8.6084 |
| Chromosome | Chromosome/Scaffold: 2 Start: 18093770 End: 18095025 |
| Description | CHIT3 - Chitinase family protein precursor, expressed |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GH19 | 90 | 283 | 0 |
| IENVVTPAFFDGIMSKVGNGCPAKGFYTRQAFIAAAQSFDAYKGTVAKREIAAMLAQFSHESGSFCYKEEIARGKYCSPSTAYPCTPGKDYYGRGPIQIT WNYNYGAAGKFLGLPLLTDPDMVARSPQVAFQCAMWFWNLNVRPVLDQGFGATTRKINGGECNGRRPAAVQSRVNYYLEFCRTLGITPGANLSC | |||
| Full Sequence |
|---|
| Protein Sequence Length: 284 Download |
| MATLRAMLKN AFILFLFTLT IMAKTVFSQQ CGTTGCAANL CCSRYGYCGT TDAYCGTGCR 60 SGPCSSSTTP IPPTPSGGAG GLNADPRDTI ENVVTPAFFD GIMSKVGNGC PAKGFYTRQA 120 FIAAAQSFDA YKGTVAKREI AAMLAQFSHE SGSFCYKEEI ARGKYCSPST AYPCTPGKDY 180 YGRGPIQITW NYNYGAAGKF LGLPLLTDPD MVARSPQVAF QCAMWFWNLN VRPVLDQGFG 240 ATTRKINGGE CNGRRPAAVQ SRVNYYLEFC RTLGITPGAN LSC* 300 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam00187 | Chitin_bind_1 | 4.0e-8 | 29 | 60 | 32 | + Chitin recognition protein. | ||
| cd00442 | lysozyme_like | 7.0e-10 | 141 | 244 | 104 | + lysozyme_like domain. This contains several members including Soluble Lytic Transglycosylases (SLT), Goose Egg-White Lysozymes (GEWL), Hen Egg-White Lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, and chitosanases. All the members are involved in the hydrolysis of beta-1,4- linked polysaccharides. | ||
| COG3179 | COG3179 | 4.0e-10 | 121 | 253 | 171 | + Predicted chitinase [General function prediction only] | ||
| pfam00182 | Glyco_hydro_19 | 3.0e-73 | 93 | 283 | 232 | + Chitinase class I. | ||
| cd00325 | chitinase_glyco_hydro_19 | 1.0e-88 | 94 | 283 | 230 | + Glycoside hydrolase family 19 chitinase domain. Chitinases are enzymes that catalyze the hydrolysis of the beta-1,4-N-acetyl-D-glucosamine linkages in chitin polymers. Family 19 chitinases are found primarily in plants (classes I, III, and IV), but some are found in bacteria. Class I and II chitinases are similar in their catalytic domains. Class I chitinases have an N-terminal cysteine-rich, chitin-binding domain which is separated from the catalytic domain by a proline and glycine-rich hinge region. Class II chitinases lack both the chitin-binding domain and the hinge region. Class IV chitinases are similar to class I chitinases but they are smaller in size due to certain deletions. Despite any significant sequence homology with lysozymes, structural analysis reveals that family 19 chitinases, together with family 46 chitosanases, are similar to several lysozymes including those from T4-phage and from goose. The structures reveal that the different enzyme groups arose from a common ancestor glycohydrolase antecedent to the procaryotic/eucaryotic divergence. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004568 | chitinase activity |
| GO:0006032 | chitin catabolic process |
| GO:0008061 | chitin binding |
| GO:0009651 | response to salt stress |
| GO:0016998 | cell wall macromolecule catabolic process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | NP_176061.1 | 0 | 1 | 283 | 1 | 280 | glycoside hydrolase family 19 protein [Arabidopsis thaliana] |
| RefSeq | NP_181888.1 | 0 | 8 | 283 | 3 | 273 | glycoside hydrolase family 19 protein [Arabidopsis thaliana] |
| RefSeq | NP_181889.1 | 0 | 1 | 283 | 1 | 281 | glycoside hydrolase family 19 protein [Arabidopsis thaliana] |
| RefSeq | NP_181890.1 | 0 | 1 | 283 | 1 | 283 | chitinase, putative [Arabidopsis thaliana] |
| Swiss-Prot | Q06209 | 0 | 6 | 283 | 2 | 268 | CHI4_BRANA RecName: Full=Basic endochitinase CHB4; Flags: Precursor |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3hbh_A | 0 | 89 | 283 | 1 | 204 | A Chain A, Class Iv Chitinase Structure From Picea Abies At 1.8a |
| PDB | 3hbe_X | 0 | 89 | 283 | 1 | 204 | A Chain A, Class Iv Chitinase Structure From Picea Abies At 1.8a |
| PDB | 3hbd_A | 0 | 89 | 283 | 1 | 204 | A Chain A, Class Iv Chitinase Structure From Picea Abies At 1.8a |
| PDB | 4dyg_B | 1.4013e-45 | 89 | 283 | 2 | 237 | A Chain A, Class Iv Chitinase Structure From Picea Abies At 1.8a |
| PDB | 4dyg_A | 1.4013e-45 | 89 | 283 | 2 | 237 | A Chain A, Class Iv Chitinase Structure From Picea Abies At 1.8a |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| chitin degradation II | 3.2.1.14-RXN | EC-3.2.1.14 | chitinase |
| chitin degradation II | RXN-12623 | EC-3.2.1.14 | chitinase |
| chitin degradation II | RXN-12624 | EC-3.2.1.14 | chitinase |
| chitin degradation III (carnivorous plants) | 3.2.1.14-RXN | EC-3.2.1.14 | chitinase |
