| Basic Information | |
|---|---|
| Species | Arabidopsis thaliana |
| Cazyme ID | AT2G45600.1 |
| Family | CE10 |
| Protein Properties | Length: 330 Molecular Weight: 36424.3 Isoelectric Point: 6.4198 |
| Chromosome | Chromosome/Scaffold: 2 Start: 18789588 End: 18790952 |
| Description | CXE carboxylesterase, putative, expressed |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| CE10 | 32 | 304 | 0 |
| KLPPTEQSKDIPLNQTNNTFIRIFKPRNIPPESKLPILVYFHGGGFILYSAASAPFHESCTKMADRLQTIILSVEYRLAPEHRLPAAYEDAVEAILWLRD QARGPINGGDCDTWLKDGVDFSKCYVMGSSSGGNIVYNVALRVVDTDLSPVKIQGLIMNQAFFGGVEPSDSESRLKDDKICPLPATHLLWSLCLPDGVDR DHVYSNPIKSSGPQEKDKMGRFPSTLINGYGGDPLVDRQRHVAEMLKGRGVHVETRFDKDGFHACELFDGNKA | |||
| Full Sequence |
|---|
| Protein Sequence Length: 330 Download |
| MEAPPPSSDP YKFLNITLNS DGSLTRHRDF PKLPPTEQSK DIPLNQTNNT FIRIFKPRNI 60 PPESKLPILV YFHGGGFILY SAASAPFHES CTKMADRLQT IILSVEYRLA PEHRLPAAYE 120 DAVEAILWLR DQARGPINGG DCDTWLKDGV DFSKCYVMGS SSGGNIVYNV ALRVVDTDLS 180 PVKIQGLIMN QAFFGGVEPS DSESRLKDDK ICPLPATHLL WSLCLPDGVD RDHVYSNPIK 240 SSGPQEKDKM GRFPSTLING YGGDPLVDRQ RHVAEMLKGR GVHVETRFDK DGFHACELFD 300 GNKAKALYET VEAFMKSCSS TGPSSNSNM* 360 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam00135 | COesterase | 8.0e-6 | 54 | 111 | 58 | + Carboxylesterase family. | ||
| cd00312 | Esterase_lipase | 5.0e-6 | 34 | 131 | 108 | + Esterases and lipases (includes fungal lipases, cholinesterases, etc.) These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These catalytic residues are responsible for the nucleophilic attack on the carbonyl carbon atom of the ester bond. In contrast with other alpha/beta hydrolase fold family members, p-nitrobenzyl esterase and acetylcholine esterase have a Glu instead of Asp at the active site carboxylate. | ||
| PRK10162 | PRK10162 | 1.0e-9 | 53 | 205 | 154 | + acetyl esterase; Provisional | ||
| COG0657 | Aes | 7.0e-35 | 30 | 314 | 292 | + Esterase/lipase [Lipid metabolism] | ||
| pfam07859 | Abhydrolase_3 | 1.0e-62 | 69 | 295 | 227 | + alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0005575 | cellular_component |
| GO:0008152 | metabolic process |
| GO:0016787 | hydrolase activity |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAM65132.1 | 0 | 1 | 329 | 1 | 329 | unknown [Arabidopsis thaliana] |
| EMBL | CAN60859.1 | 0 | 3 | 320 | 5 | 332 | hypothetical protein [Vitis vinifera] |
| RefSeq | NP_566047.1 | 0 | 1 | 329 | 1 | 329 | hydrolase [Arabidopsis thaliana] |
| RefSeq | XP_002277011.1 | 0 | 4 | 320 | 6 | 332 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002320078.1 | 0 | 9 | 329 | 2 | 325 | predicted protein [Populus trichocarpa] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 2o7v_A | 0 | 6 | 320 | 14 | 333 | A Chain A, Crystal Structure Of Medicago Truncatula Ugt71g1 |
| PDB | 2o7r_A | 0 | 6 | 320 | 14 | 333 | A Chain A, Plant Carboxylesterase Aecxe1 From Actinidia Eriantha With Acyl Adduct |
| PDB | 3ed1_F | 7e-33 | 59 | 286 | 105 | 317 | A Chain A, Plant Carboxylesterase Aecxe1 From Actinidia Eriantha With Acyl Adduct |
| PDB | 3ed1_E | 7e-33 | 59 | 286 | 105 | 317 | A Chain A, Plant Carboxylesterase Aecxe1 From Actinidia Eriantha With Acyl Adduct |
| PDB | 3ed1_D | 7e-33 | 59 | 286 | 105 | 317 | A Chain A, Plant Carboxylesterase Aecxe1 From Actinidia Eriantha With Acyl Adduct |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| formononetin biosynthesis | RXN-3284 | EC-4.2.1.105 | 2-hydroxyisoflavanone dehydratase |
| formononetin biosynthesis | RXN-3625 | - | 2,7-dihydroxy-4'-methoxyisoflavanone dehydratase |
| isoflavonoid biosynthesis I | RXN-3284 | EC-4.2.1.105 | 2-hydroxyisoflavanone dehydratase |
| isoflavonoid biosynthesis II | RXN-3303 | EC-4.2.1.105 | 2-hydroxyisoflavanone dehydratase |
| isoflavonoid biosynthesis II | RXN-5502 | - | 2,7,5-trihydroxy-4'-methoxyisoflavanone dehydratase |
| Hydropathy |
|---|
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| EV566807 | 231 | 1 | 231 | 0 |
| DK520487 | 208 | 109 | 316 | 0 |
| DY288919 | 319 | 7 | 315 | 0 |
| DY274643 | 319 | 7 | 315 | 0 |
| AV830865 | 179 | 1 | 179 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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