| Basic Information | |
|---|---|
| Species | Arabidopsis thaliana |
| Cazyme ID | AT3G03650.1 |
| Family | GT47 |
| Protein Properties | Length: 500 Molecular Weight: 57145.3 Isoelectric Point: 9.7576 |
| Chromosome | Chromosome/Scaffold: 3 Start: 884133 End: 886410 |
| Description | exostosin family domain containing protein, expressed |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 119 | 437 | 0 |
| RPLKVYMYDMSPEFHFGLLGWKPERNGVVWPDIRVNVPHHPGGLNLQHSVEYWLTLDLLFSELPEDSRSSRAAIRVKNSSEADVVFVPFFSSLSYNRFSK VNQKQKKSQDKELQENVVKYVTSQKEWKTSGGKDHVIMAHHPNSMSTARHKLFPAMFVVADFGRYSPHVANVDKDIVAPYKHLVPSYVNDTSGFDGRPIL LYFQGAIYRKAGGFVRQELYNLLKEEKDVHFSFGSVRNHGISKAGEGMRSSKFCLNIAGDTPSSNRLFDAIASHCIPVIISDDIELPYEDVLNYNEFCLF VRSSDALKKGFLMGLVRSI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 500 Download |
| MGEKTNSRYL GVIITRKSII FLFISIITVL SWFFIFSSTN PNRVLDHISV SESTDVPLII 60 IKNSNSSPQN NAPKPQNREG AETEEPIKEN RGGTKTESSM NQNRGETLRC IQRVSPSPRP 120 LKVYMYDMSP EFHFGLLGWK PERNGVVWPD IRVNVPHHPG GLNLQHSVEY WLTLDLLFSE 180 LPEDSRSSRA AIRVKNSSEA DVVFVPFFSS LSYNRFSKVN QKQKKSQDKE LQENVVKYVT 240 SQKEWKTSGG KDHVIMAHHP NSMSTARHKL FPAMFVVADF GRYSPHVANV DKDIVAPYKH 300 LVPSYVNDTS GFDGRPILLY FQGAIYRKAG GFVRQELYNL LKEEKDVHFS FGSVRNHGIS 360 KAGEGMRSSK FCLNIAGDTP SSNRLFDAIA SHCIPVIISD DIELPYEDVL NYNEFCLFVR 420 SSDALKKGFL MGLVRSIGRE EYNKMWLRLK EVERYFDLRF PVKDDEGDYA VQMIWKAVAR 480 KAPLVKMKVH RFQRFTRPF* 540 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 2.0e-55 | 117 | 437 | 331 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0003824 | catalytic activity |
| GO:0009561 | megagametogenesis |
| GO:0016020 | membrane |
| GO:0048868 | pollen tube development |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAX33321.1 | 0 | 58 | 497 | 59 | 490 | secondary cell wall-related glycosyltransferase family 47 [Populus tremula x Populus tremuloides] |
| RefSeq | NP_187015.1 | 0 | 1 | 499 | 1 | 499 | EDA5 (embryo sac development arrest 5); catalytic [Arabidopsis thaliana] |
| RefSeq | NP_190126.1 | 0 | 109 | 496 | 67 | 454 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_002319201.1 | 0 | 1 | 496 | 3 | 450 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002530948.1 | 0 | 108 | 499 | 97 | 483 | catalytic, putative [Ricinus communis] |
