| Basic Information | |
|---|---|
| Species | Arabidopsis thaliana |
| Cazyme ID | AT3G07620.1 |
| Family | GT47 |
| Protein Properties | Length: 471 Molecular Weight: 54691 Isoelectric Point: 8.6388 |
| Chromosome | Chromosome/Scaffold: 3 Start: 2433267 End: 2434988 |
| Description | exostosin family protein, putative, expressed |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 140 | 422 | 0 |
| EKMFKIYVYEEGDPPIFHYGLCKDIYSMEGLFLNFMENDVLKYRTRDPDKAHVYFLPFSVVMILHHLFDPVVRDKAVLERVIADYVQIISKKYPYWNTSD GFDHFMLSCHDWGHRATWYVKKLFFNSIRVLCNANISEYFNPEKDAPFPEINLLTGDINNLTGGLDPISRTTLAFFAGKSHGKIRPVLLNHWKEKDKDIL VYENLPDGLDYTEMMRKSRFCICPSGHEVASPRVPEAIYSGCVPVLISENYVLPFSDVLNWEKFSVSVSVKEIPELKRILMDI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 471 Download |
| MRDYIPKYLN AFLLAFATFA VGFAIFIAKD SNSSSHLYFS TSSSLWTSSF SPAFITVSIF 60 LTVHRFREKR KRNGSNPGSG YWKRDGKVEA ELATARVLIR EAQLNYSSTT SSPLGDEDYV 120 PHGDIYRNPY AFHRSYLLME KMFKIYVYEE GDPPIFHYGL CKDIYSMEGL FLNFMENDVL 180 KYRTRDPDKA HVYFLPFSVV MILHHLFDPV VRDKAVLERV IADYVQIISK KYPYWNTSDG 240 FDHFMLSCHD WGHRATWYVK KLFFNSIRVL CNANISEYFN PEKDAPFPEI NLLTGDINNL 300 TGGLDPISRT TLAFFAGKSH GKIRPVLLNH WKEKDKDILV YENLPDGLDY TEMMRKSRFC 360 ICPSGHEVAS PRVPEAIYSG CVPVLISENY VLPFSDVLNW EKFSVSVSVK EIPELKRILM 420 DIPEERYMRL YEGVKKVKRH ILVNDPPKRY DVFNMIIHSI WLRRLNVKLL * 480 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 3.0e-65 | 139 | 422 | 302 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0003824 | catalytic activity |
| GO:0008150 | biological_process |
| GO:0012505 | endomembrane system |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CBI28482.1 | 0 | 70 | 469 | 226 | 634 | unnamed protein product [Vitis vinifera] |
| RefSeq | NP_187419.1 | 0 | 1 | 470 | 1 | 470 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_002264111.1 | 0 | 139 | 469 | 1 | 330 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002320537.1 | 0 | 87 | 469 | 13 | 393 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002524592.1 | 0 | 87 | 470 | 6 | 387 | catalytic, putative [Ricinus communis] |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |
