| Basic Information | |
|---|---|
| Species | Arabidopsis thaliana |
| Cazyme ID | AT3G11540.2 |
| Family | GT41 |
| Protein Properties | Length: 733 Molecular Weight: 81053.5 Isoelectric Point: 6.4599 |
| Chromosome | Chromosome/Scaffold: 3 Start: 3632162 End: 3637867 |
| Description | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase SPINDLY, putative, expressed |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT41 | 150 | 665 | 0 |
| CLAIVLTDLGTSLKLAGNTQEGIQKYYEALKIDPHYAPAYYNLGVVYSEMMQYDNALSCYEKAALERPMYAEAYCNMDAGNITMAIDAYEECLKIDPDSR NAGQNRLLAMNYINEGLDDKLFEAHRDWGWRFTRLHPQYTSWDNLKDPERPITIGYISPDFFTHSVSYFIEAPLTHHDYTKYKVVVYSAVVKADAKTYRF RDKVLKKGGVWKDIYGIDEKKIASMVREDKIDILVELTGHTANNKLGTMACRPAPVQVTWIGYPNTTGLPTVDYRITDSLADPPDTKQKQVEELVRLPDC FLCYTPSPEAGPVCPTPALSNGFVTFGSFNNLAKITPKVLQVWARILCAVPNSRLVVKCKPFCCDSIRQRFLTTLEQLGLESKRVDLLPLILFNHDHMQA YSLMDISLDTFPYAGTTTTCESLYMGVPCVTMAGSVHAHNVGVSLLTKVGLGHLVAKNEDEYVQLSVDLASDVTALSKLRMSLRDLMAGSPVCNGPSFAV GLESAYRNMWKKYCKG | |||
| Full Sequence |
|---|
| Protein Sequence Length: 733 Download |
| MVGLEDDTER ERSPVVENGF SNGSRSSSSS AGVLSPSRKV TQGNDTLSYA NILRARNKFA 60 DALALYEAML EKDSKNVEAH IGKGICLQTQ NKGNLAFDCF SEAIRLDPHN ACALTHCGIL 120 HKEEGRLVEA AESYQKALMA DASYKPAAEC LAIVLTDLGT SLKLAGNTQE GIQKYYEALK 180 IDPHYAPAYY NLGVVYSEMM QYDNALSCYE KAALERPMYA EAYCNMDAGN ITMAIDAYEE 240 CLKIDPDSRN AGQNRLLAMN YINEGLDDKL FEAHRDWGWR FTRLHPQYTS WDNLKDPERP 300 ITIGYISPDF FTHSVSYFIE APLTHHDYTK YKVVVYSAVV KADAKTYRFR DKVLKKGGVW 360 KDIYGIDEKK IASMVREDKI DILVELTGHT ANNKLGTMAC RPAPVQVTWI GYPNTTGLPT 420 VDYRITDSLA DPPDTKQKQV EELVRLPDCF LCYTPSPEAG PVCPTPALSN GFVTFGSFNN 480 LAKITPKVLQ VWARILCAVP NSRLVVKCKP FCCDSIRQRF LTTLEQLGLE SKRVDLLPLI 540 LFNHDHMQAY SLMDISLDTF PYAGTTTTCE SLYMGVPCVT MAGSVHAHNV GVSLLTKVGL 600 GHLVAKNEDE YVQLSVDLAS DVTALSKLRM SLRDLMAGSP VCNGPSFAVG LESAYRNMWK 660 KYCKGEVPSL RRMEMLQKEV HDDPLISKDL GPSRVSVTGE ATPSLKANGS APVPSSLPTQ 720 SPQLSKRMDS TS* 780 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam13844 | Glyco_transf_41 | 5.0e-16 | 303 | 450 | 151 | + Glycosyl transferase family 41. This family of glycosyltransferases includes O-linked beta-N-acetylglucosamine (O-GlcNAc) transferase, an enzyme which catalyzes the addition of O-GlcNAc to serine and threonine residues. In addition to its function as an O-GlcNAc transferase, human OGT, also appears to proteolytically cleave the epigenetic cell-cycle regulator HCF-1. | ||
| cd00189 | TPR | 1.0e-16 | 44 | 141 | 98 | + Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]-X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans in various subcellular locations; involved in a variety of functions including protein-protein interactions, but common features in the interaction partners have not been defined; involved in chaperone, cell-cycle, transciption, and protein transport complexes; the number of TPR motifs varies among proteins (1,3-11,13 15,16,19); 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accomodate an alpha-helix of a target protein; it has been proposed that TPR proteins preferably interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes; examples of TPR-proteins include, Cdc16p, Cdc23p and Cdc27p components of the cyclosome/APC, the Pex5p/Pas10p receptor for peroxisomal targeting signals, the Tom70p co-receptor for mitochondrial targeting signals, Ser/Thr phosphatase 5C and the p110 subunit of O-GlcNAc transferase; three copies of the repeat are present here | ||
| cd00189 | TPR | 2.0e-18 | 154 | 247 | 99 | + Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]-X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans in various subcellular locations; involved in a variety of functions including protein-protein interactions, but common features in the interaction partners have not been defined; involved in chaperone, cell-cycle, transciption, and protein transport complexes; the number of TPR motifs varies among proteins (1,3-11,13 15,16,19); 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accomodate an alpha-helix of a target protein; it has been proposed that TPR proteins preferably interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes; examples of TPR-proteins include, Cdc16p, Cdc23p and Cdc27p components of the cyclosome/APC, the Pex5p/Pas10p receptor for peroxisomal targeting signals, the Tom70p co-receptor for mitochondrial targeting signals, Ser/Thr phosphatase 5C and the p110 subunit of O-GlcNAc transferase; three copies of the repeat are present here | ||
| pfam13844 | Glyco_transf_41 | 5.0e-24 | 473 | 659 | 192 | + Glycosyl transferase family 41. This family of glycosyltransferases includes O-linked beta-N-acetylglucosamine (O-GlcNAc) transferase, an enzyme which catalyzes the addition of O-GlcNAc to serine and threonine residues. In addition to its function as an O-GlcNAc transferase, human OGT, also appears to proteolytically cleave the epigenetic cell-cycle regulator HCF-1. | ||
| COG3914 | Spy | 1.0e-88 | 95 | 662 | 580 | + Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones] | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0005515 | protein binding |
| GO:0005634 | nucleus |
| GO:0005737 | cytoplasm |
| GO:0005829 | cytosol |
| GO:0009736 | cytokinin mediated signaling pathway |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | NP_187761.1 | 0 | 1 | 259 | 1 | 264 | SPY (SPINDLY); protein N-acetylglucosaminyltransferase/ protein binding / transferase, transferring glycosyl groups [Arabidopsis thaliana] |
| RefSeq | NP_187761.1 | 0 | 58 | 732 | 201 | 914 | SPY (SPINDLY); protein N-acetylglucosaminyltransferase/ protein binding / transferase, transferring glycosyl groups [Arabidopsis thaliana] |
| RefSeq | NP_974286.1 | 0 | 1 | 732 | 1 | 732 | SPY (SPINDLY); protein N-acetylglucosaminyltransferase/ protein binding / transferase, transferring glycosyl groups [Arabidopsis thaliana] |
| RefSeq | XP_002281883.1 | 0 | 10 | 259 | 12 | 267 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002281883.1 | 0 | 58 | 721 | 204 | 906 | PREDICTED: hypothetical protein [Vitis vinifera] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 4gz6_D | 5e-38 | 108 | 451 | 6 | 386 | A Chain A, Higher-density Crystal Structure Of Potato Endo-1,3-beta-glucanase |
| PDB | 4gz6_D | 3e-24 | 473 | 668 | 524 | 715 | A Chain A, Higher-density Crystal Structure Of Potato Endo-1,3-beta-glucanase |
| PDB | 4gz6_C | 5e-38 | 108 | 451 | 6 | 386 | A Chain A, Higher-density Crystal Structure Of Potato Endo-1,3-beta-glucanase |
| PDB | 4gz6_C | 3e-24 | 473 | 668 | 524 | 715 | A Chain A, Higher-density Crystal Structure Of Potato Endo-1,3-beta-glucanase |
| PDB | 4gz6_B | 5e-38 | 108 | 451 | 6 | 386 | A Chain A, Higher-density Crystal Structure Of Potato Endo-1,3-beta-glucanase |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| DY295408 | 400 | 243 | 640 | 0 |
| HO781209 | 357 | 310 | 666 | 0 |
| HO781209 | 123 | 207 | 324 | 0 |
| GO856896 | 300 | 380 | 679 | 0 |
| DT769000 | 296 | 262 | 557 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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