| Basic Information | |
|---|---|
| Species | Arabidopsis thaliana |
| Cazyme ID | AT3G45400.1 |
| Family | GT47 |
| Protein Properties | Length: 476 Molecular Weight: 54447.2 Isoelectric Point: 9.1999 |
| Chromosome | Chromosome/Scaffold: 3 Start: 16651963 End: 16653678 |
| Description | exostosin family domain containing protein, expressed |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 81 | 398 | 0 |
| LKVYMYNMDPEFHFGLLDWKKKEGSDSSVWPDIQKYIPPYPGGLNLQHSIEYWLTLDLLASEYENAPRSVAAKRVYNSSEADVIFVPFFSSLSYNRFSKV NPHQKTSRNKDLQGKLVTFLTAQEEWKRSGGRDHVVLAHHPNSMLDARNKLFPAMFILSDFGRYPPTVANVEKDVIAPYKHVIKAYENDTSGFDSRPILL YFQGAIYRKDGGFVRQELFYLLQDEKDVHFSFGSVRNGGINKASQGMHNSKFCLNIAGDTPSSNRLFDAIASHCVPVIISDDIELPFEDVIDYSEFSVFV RTSDALKENFLVNLIRGI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 476 Download |
| MAMVEKNSSA IGYVARNLLL SLFVVTTILF ALSCYFVLRS TAHNRFLSST FPSKSFVDVR 60 PEKANCRCVK DEKSSVIAGP LKVYMYNMDP EFHFGLLDWK KKEGSDSSVW PDIQKYIPPY 120 PGGLNLQHSI EYWLTLDLLA SEYENAPRSV AAKRVYNSSE ADVIFVPFFS SLSYNRFSKV 180 NPHQKTSRNK DLQGKLVTFL TAQEEWKRSG GRDHVVLAHH PNSMLDARNK LFPAMFILSD 240 FGRYPPTVAN VEKDVIAPYK HVIKAYENDT SGFDSRPILL YFQGAIYRKD GGFVRQELFY 300 LLQDEKDVHF SFGSVRNGGI NKASQGMHNS KFCLNIAGDT PSSNRLFDAI ASHCVPVIIS 360 DDIELPFEDV IDYSEFSVFV RTSDALKENF LVNLIRGITK EEWTRMWNRL KEVEKYYEFH 420 FPSKVDDAVQ MIWQAIARKV PGVKMRIHKS RRYSGSVSET GKESRWSSLI PRSFW* 480 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 2.0e-56 | 80 | 398 | 329 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0003824 | catalytic activity |
| GO:0008150 | biological_process |
| GO:0012505 | endomembrane system |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CAN68950.1 | 0 | 3 | 475 | 1 | 488 | hypothetical protein [Vitis vinifera] |
| RefSeq | NP_190126.1 | 0 | 1 | 475 | 1 | 475 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_002268382.1 | 0 | 3 | 475 | 1 | 488 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002319201.1 | 0 | 1 | 454 | 1 | 450 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002530948.1 | 0 | 80 | 465 | 109 | 491 | catalytic, putative [Ricinus communis] |
