| Basic Information | |
|---|---|
| Species | Arabidopsis thaliana |
| Cazyme ID | AT3G57630.1 |
| Family | GT47 |
| Protein Properties | Length: 794 Molecular Weight: 90931.7 Isoelectric Point: 6.4049 |
| Chromosome | Chromosome/Scaffold: 3 Start: 21339302 End: 21343796 |
| Description | exostosin family protein, putative, expressed |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 345 | 698 | 0 |
| KKRPLIYIYDLPPDFNSLLIEGRHFKFECVNRIYDERNATVWTDYLYGSQMAFYENILATAHRTMNGEEADFFFVPVLDSCIINRADDAPHINMQNHTGL RSSLTLEFYKRAYEHIVEKYPYWNRSAGRDHIWFFSWDEGACYAPKEIWNSMMLVHWGNTNSKHNHSTTAYFGDNWDDISDERRGDHPCFDPRKDLVIPA WKVPDPYSMRKNYWERPREKRKTLFYFNGNLGPAYEKGRPEDSYSMGIRQKLAEEFGSSPNKEGKLGKQHAEDVIVTPLRSDNYHKDIANSIFCGAFPGD GWSGRMEDSILQGCVPVIIQDGIYLPYENMLNYESFAVRVNEDDIPNLINTLRG | |||
| Full Sequence |
|---|
| Protein Sequence Length: 794 Download |
| MFSHQKWKFS WSQIATVASV IVLVSLVHLF LGPVVPSFDS ITVRQAQNLC GPSNESISQV 60 TKNSSQSLVV VAFDRRFPAD SHGAVVYRNA SWKAEIGQWL SSCDAVAKEV DIIEPIGGRK 120 CMSDCSGQGV CNHEFGLCRC FHGFTGEDCS QKLRLDCNYE KTPEMPYGKW VVSICSRHCD 180 TTRAMCFCGE GTKYPNRPVP ESCGFQINSP TNPDEPKMTD WSKPDLDILT TNSSKQGWCN 240 VDPEDAYAMK VKIKEECDCK YDCLWGRFCE IPVQCTCVNQ CSGHGKCRGG FCQCDKGWFG 300 TDCSIPSTLS TVGEWPQWLR PAHLEVPSEK NVPGNLINLS AVVKKKRPLI YIYDLPPDFN 360 SLLIEGRHFK FECVNRIYDE RNATVWTDYL YGSQMAFYEN ILATAHRTMN GEEADFFFVP 420 VLDSCIINRA DDAPHINMQN HTGLRSSLTL EFYKRAYEHI VEKYPYWNRS AGRDHIWFFS 480 WDEGACYAPK EIWNSMMLVH WGNTNSKHNH STTAYFGDNW DDISDERRGD HPCFDPRKDL 540 VIPAWKVPDP YSMRKNYWER PREKRKTLFY FNGNLGPAYE KGRPEDSYSM GIRQKLAEEF 600 GSSPNKEGKL GKQHAEDVIV TPLRSDNYHK DIANSIFCGA FPGDGWSGRM EDSILQGCVP 660 VIIQDGIYLP YENMLNYESF AVRVNEDDIP NLINTLRGFS EAEIQFRLGN VKELWQRFLF 720 RDSILLEAER QKATYGHEED WAVQFSKLKH DDIFATIIQT LHFKLHNDPW RREQAVNRTK 780 DYGLPQECLH KTS* 840 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam07974 | EGF_2 | 9.0e-5 | 275 | 303 | 31 | + EGF-like domain. This family contains EGF domains found in a variety of extracellular proteins. | ||
| pfam03016 | Exostosin | 9.0e-65 | 344 | 699 | 359 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0003824 | catalytic activity |
| GO:0005515 | protein binding |
| GO:0012505 | endomembrane system |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CAB41192.1 | 0 | 1 | 793 | 1 | 736 | putative protein [Arabidopsis thaliana] |
| EMBL | CBI29877.1 | 0 | 2 | 792 | 31 | 821 | unnamed protein product [Vitis vinifera] |
| RefSeq | NP_191322.3 | 0 | 1 | 793 | 1 | 793 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | NP_974452.1 | 0 | 1 | 793 | 1 | 791 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_002277596.1 | 0 | 2 | 792 | 3 | 793 | PREDICTED: hypothetical protein [Vitis vinifera] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3a7q_A | 0.008 | 277 | 331 | 537 | 586 | B Chain B, Structural Basis For Specific Recognition Of Reelin By Its Receptors |
| PDB | 2e26_A | 0.008 | 277 | 331 | 537 | 586 | A Chain A, Crystal Structure Of Two Repeat Fragment Of Reelin |
