| Basic Information | |
|---|---|
| Species | Arabidopsis thaliana |
| Cazyme ID | AT3G57630.2 |
| Family | GT47 |
| Protein Properties | Length: 792 Molecular Weight: 90745.5 Isoelectric Point: 6.4676 |
| Chromosome | Chromosome/Scaffold: 3 Start: 21339302 End: 21343152 |
| Description | exostosin family protein, putative, expressed |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 343 | 696 | 0 |
| KKRPLIYIYDLPPDFNSLLIEGRHFKFECVNRIYDERNATVWTDYLYGSQMAFYENILATAHRTMNGEEADFFFVPVLDSCIINRADDAPHINMQNHTGL RSSLTLEFYKRAYEHIVEKYPYWNRSAGRDHIWFFSWDEGACYAPKEIWNSMMLVHWGNTNSKHNHSTTAYFGDNWDDISDERRGDHPCFDPRKDLVIPA WKVPDPYSMRKNYWERPREKRKTLFYFNGNLGPAYEKGRPEDSYSMGIRQKLAEEFGSSPNKEGKLGKQHAEDVIVTPLRSDNYHKDIANSIFCGAFPGD GWSGRMEDSILQGCVPVIIQDGIYLPYENMLNYESFAVRVNEDDIPNLINTLRG | |||
| Full Sequence |
|---|
| Protein Sequence Length: 792 Download |
| MFSHQKWKFS WSQIATVASV IVLVSLVHLF LGPVVPSFDS ITVRQAQNLC GPSNESISQV 60 TKNSSQSLVV VAFDRRFPAD SHGAVVYRNA SWKAEIGQWL SSCDAVAKEV DIIEPIGGRK 120 CMSDCSGQGV CNHEFGLCRC FHGFTDCSQK LRLDCNYEKT PEMPYGKWVV SICSRHCDTT 180 RAMCFCGEGT KYPNRPVPES CGFQINSPTN PDEPKMTDWS KPDLDILTTN SSKQGWCNVD 240 PEDAYAMKVK IKEECDCKYD CLWGRFCEIP VQCTCVNQCS GHGKCRGGFC QCDKGWFGTD 300 CSIPSTLSTV GEWPQWLRPA HLEVPSEKNV PGNLINLSAV VKKKRPLIYI YDLPPDFNSL 360 LIEGRHFKFE CVNRIYDERN ATVWTDYLYG SQMAFYENIL ATAHRTMNGE EADFFFVPVL 420 DSCIINRADD APHINMQNHT GLRSSLTLEF YKRAYEHIVE KYPYWNRSAG RDHIWFFSWD 480 EGACYAPKEI WNSMMLVHWG NTNSKHNHST TAYFGDNWDD ISDERRGDHP CFDPRKDLVI 540 PAWKVPDPYS MRKNYWERPR EKRKTLFYFN GNLGPAYEKG RPEDSYSMGI RQKLAEEFGS 600 SPNKEGKLGK QHAEDVIVTP LRSDNYHKDI ANSIFCGAFP GDGWSGRMED SILQGCVPVI 660 IQDGIYLPYE NMLNYESFAV RVNEDDIPNL INTLRGFSEA EIQFRLGNVK ELWQRFLFRD 720 SILLEAERQK ATYGHEEDWA VQFSKLKHDD IFATIIQTLH FKLHNDPWRR EQAVNRTKDY 780 GLPQECLHKT S* 840 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam07974 | EGF_2 | 9.0e-5 | 273 | 301 | 31 | + EGF-like domain. This family contains EGF domains found in a variety of extracellular proteins. | ||
| pfam03016 | Exostosin | 1.0e-64 | 342 | 697 | 359 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0003824 | catalytic activity |
| GO:0012505 | endomembrane system |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CAB41192.1 | 0 | 1 | 791 | 1 | 736 | putative protein [Arabidopsis thaliana] |
| EMBL | CBI29877.1 | 0 | 2 | 790 | 31 | 821 | unnamed protein product [Vitis vinifera] |
| RefSeq | NP_191322.3 | 0 | 1 | 791 | 1 | 793 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | NP_974452.1 | 0 | 1 | 791 | 1 | 791 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_002277596.1 | 0 | 2 | 790 | 3 | 793 | PREDICTED: hypothetical protein [Vitis vinifera] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3a7q_A | 0.007 | 275 | 329 | 537 | 586 | B Chain B, Structural Basis For Specific Recognition Of Reelin By Its Receptors |
| PDB | 2e26_A | 0.007 | 275 | 329 | 537 | 586 | A Chain A, Crystal Structure Of Two Repeat Fragment Of Reelin |
