| Basic Information | |
|---|---|
| Species | Arabidopsis thaliana |
| Cazyme ID | AT4G01040.1 |
| Family | GH18 |
| Protein Properties | Length: 431 Molecular Weight: 49142.4 Isoelectric Point: 9.4461 |
| Chromosome | Chromosome/Scaffold: 4 Start: 453369 End: 455548 |
| Description | chitinase domain-containing protein 1 precursor, putative, expressed |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GH18 | 102 | 421 | 5.8e-30 |
| PVLAYITPWNSKGYDMAKIFNSKFTHLSPVWYDLKSQGSGLVLEGRHNADKGWIQELRSRGNALILPRVVLEAIPGEMLNKKKLREKAISLIVTECKEME YNGIVLESWSRWAAYGVLHDPDLRKMALKFVKQLGDALHSTSSPRNNQQHMQFMYVVGPPRSEKLQMYDFGPEDLQFLKDSVDGFSLMTYDFSNPQNPGP NAPVKWIDLTLKLLLGSSNNIDSNIARKVLLGINFYGNDFVISGDSGGGGAITGRDYLALLQKHKPTFRWDKESGEHLFMYRDDKNIKHAVFYPTLMSIL LRLENARLWGIGISIWEIGQ | |||
| Full Sequence |
|---|
| Protein Sequence Length: 431 Download |
| MARRRRSSAA ESLKRRNDGY ESLCQVVQQD SDRRLITIFV IFFIVIPAVS IAVYKVKFAD 60 RVIQTESSIR QKGIVKTDIN FQEILTEHSK ASENSTRHYD YPVLAYITPW NSKGYDMAKI 120 FNSKFTHLSP VWYDLKSQGS GLVLEGRHNA DKGWIQELRS RGNALILPRV VLEAIPGEML 180 NKKKLREKAI SLIVTECKEM EYNGIVLESW SRWAAYGVLH DPDLRKMALK FVKQLGDALH 240 STSSPRNNQQ HMQFMYVVGP PRSEKLQMYD FGPEDLQFLK DSVDGFSLMT YDFSNPQNPG 300 PNAPVKWIDL TLKLLLGSSN NIDSNIARKV LLGINFYGND FVISGDSGGG GAITGRDYLA 360 LLQKHKPTFR WDKESGEHLF MYRDDKNIKH AVFYPTLMSI LLRLENARLW GIGISIWEIG 420 QGLDYFFDLL * 480 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam00704 | Glyco_hydro_18 | 1.0e-6 | 103 | 421 | 356 | + Glycosyl hydrolases family 18. | ||
| COG3858 | COG3858 | 3.0e-16 | 180 | 430 | 257 | + Predicted glycosyl hydrolase [General function prediction only] | ||
| cd02874 | GH18_CFLE_spore_hydrolase | 6.0e-23 | 103 | 430 | 346 | + Cortical fragment-lytic enzyme (CFLE) is a peptidoglycan hydrolase involved in bacterial endospore germination. CFLE is expressed as an inactive preprotein (called SleB) in the forespore compartment of sporulating cells. SleB translocates across the forespore inner membrane and is deposited as a mature enzyme in the cortex layer of the spore. As part of a sensory mechanism capable of initiating germination, CFLE degrades a spore-specific peptidoglycan constituent called muramic-acid delta-lactam that comprises the outer cortex. CFLE has a C-terminal glycosyl hydrolase family 18 (GH18) catalytic domain as well as two N-terminal LysM peptidoglycan-binding domains. In addition to SleB, this family includes YaaH, YdhD, and YvbX from Bacillus subtilis. | ||
| smart00636 | Glyco_18 | 1.0e-30 | 103 | 421 | 357 | + Glyco_18 domain. | ||
| cd02876 | GH18_SI-CLP | 3.0e-159 | 99 | 430 | 337 | + Stabilin-1 interacting chitinase-like protein (SI-CLP) is a eukaryotic chitinase-like protein of unknown function that interacts with the endocytic/sorting transmembrane receptor stabilin-1 and is secreted from the lysosome. SI-CLP has a glycosyl hydrolase family 18 (GH18) domain but lacks a chitin-binding domain. The catalytic amino acids of the GH18 domain are not conserved in SI-CLP, similar to the chitolectins YKL-39, YKL-40, and YM1/2. Human SI-CLP is sorted to late endosomes and secretory lysosomes in alternatively activated macrophages. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0003824 | catalytic activity |
| GO:0004553 | hydrolase activity, hydrolyzing O-glycosyl compounds |
| GO:0004568 | chitinase activity |
| GO:0005575 | cellular_component |
| GO:0005975 | carbohydrate metabolic process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAB61039.1 | 0 | 1 | 426 | 27 | 434 | A_IG002N01.31 gene product [Arabidopsis thaliana] |
| EMBL | CBI40499.1 | 0 | 1 | 430 | 1 | 435 | unnamed protein product [Vitis vinifera] |
| RefSeq | NP_192013.1 | 0 | 1 | 430 | 1 | 430 | glycosyl hydrolase family 18 protein [Arabidopsis thaliana] |
| RefSeq | XP_002320856.1 | 0 | 57 | 430 | 27 | 399 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002523373.1 | 0 | 65 | 430 | 67 | 432 | chitinase, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3bxw_A | 0 | 55 | 430 | 37 | 393 | B Chain B, Crystal Structure Of Stabilin-1 Interacting Chitinase-Like Protein, Si-Clp |
| PDB | 3bxw_B | 0 | 55 | 430 | 37 | 393 | B Chain B, Crystal Structure Of Stabilin-1 Interacting Chitinase-Like Protein, Si-Clp |
| PDB | 3cz8_B | 0.000005 | 178 | 419 | 88 | 308 | A Chain A, Crystal Structure Of Putative Sporulation-Specific Glycosylase Ydhd From Bacillus Subtilis |
| PDB | 3cz8_A | 0.000005 | 178 | 419 | 88 | 308 | A Chain A, Crystal Structure Of Putative Sporulation-Specific Glycosylase Ydhd From Bacillus Subtilis |
