| Basic Information | |
|---|---|
| Species | Arabidopsis thaliana |
| Cazyme ID | AT4G01700.1 |
| Family | GH19 |
| Protein Properties | Length: 281 Molecular Weight: 31464.7 Isoelectric Point: 9.0041 |
| Chromosome | Chromosome/Scaffold: 4 Start: 732313 End: 733510 |
| Description | CHIT10 - Chitinase family protein precursor, expressed |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GH19 | 39 | 273 | 0 |
| MSLVPRTLYDQIFIHKDNNACPAKGFYPYEAFVEATRSFPKFGSVGNFWTRRREVAAFLAQISHETTGGWATAPDGPYAWGLCFKEEVSPQSNYCDASNK DWPCVSGKSYKGRGPIQLSWNYNYGQAGRALGFDGLQNPELVANNSVLAFKTALWFWMTEQTPKPSCHNVMVNRYRPTKADRAANRTVGYGLVTNIINGG LECGIPGDGRVTDRVGYFQRYAQLFKVTTGPNLDC | |||
| Full Sequence |
|---|
| Protein Sequence Length: 281 Download |
| MEKQISLLLC LLLFIFSISS SLHETEARKH NKYKPAPIMS LVPRTLYDQI FIHKDNNACP 60 AKGFYPYEAF VEATRSFPKF GSVGNFWTRR REVAAFLAQI SHETTGGWAT APDGPYAWGL 120 CFKEEVSPQS NYCDASNKDW PCVSGKSYKG RGPIQLSWNY NYGQAGRALG FDGLQNPELV 180 ANNSVLAFKT ALWFWMTEQT PKPSCHNVMV NRYRPTKADR AANRTVGYGL VTNIINGGLE 240 CGIPGDGRVT DRVGYFQRYA QLFKVTTGPN LDCENQRPFS * 300 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| COG3179 | COG3179 | 2.0e-8 | 88 | 239 | 171 | + Predicted chitinase [General function prediction only] | ||
| cd00442 | lysozyme_like | 8.0e-13 | 94 | 235 | 142 | + lysozyme_like domain. This contains several members including Soluble Lytic Transglycosylases (SLT), Goose Egg-White Lysozymes (GEWL), Hen Egg-White Lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, and chitosanases. All the members are involved in the hydrolysis of beta-1,4- linked polysaccharides. | ||
| cd00325 | chitinase_glyco_hydro_19 | 5.0e-125 | 42 | 273 | 232 | + Glycoside hydrolase family 19 chitinase domain. Chitinases are enzymes that catalyze the hydrolysis of the beta-1,4-N-acetyl-D-glucosamine linkages in chitin polymers. Family 19 chitinases are found primarily in plants (classes I, III, and IV), but some are found in bacteria. Class I and II chitinases are similar in their catalytic domains. Class I chitinases have an N-terminal cysteine-rich, chitin-binding domain which is separated from the catalytic domain by a proline and glycine-rich hinge region. Class II chitinases lack both the chitin-binding domain and the hinge region. Class IV chitinases are similar to class I chitinases but they are smaller in size due to certain deletions. Despite any significant sequence homology with lysozymes, structural analysis reveals that family 19 chitinases, together with family 46 chitosanases, are similar to several lysozymes including those from T4-phage and from goose. The structures reveal that the different enzyme groups arose from a common ancestor glycohydrolase antecedent to the procaryotic/eucaryotic divergence. | ||
| pfam00182 | Glyco_hydro_19 | 3.0e-125 | 41 | 273 | 233 | + Chitinase class I. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004568 | chitinase activity |
| GO:0005618 | cell wall |
| GO:0005975 | carbohydrate metabolic process |
| GO:0006032 | chitin catabolic process |
| GO:0016998 | cell wall macromolecule catabolic process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CAA57773.1 | 0 | 10 | 279 | 12 | 277 | chitinase (class II) [Arachis hypogaea] |
| RefSeq | NP_171738.1 | 0 | 1 | 280 | 1 | 272 | chitinase, putative [Arabidopsis thaliana] |
| RefSeq | NP_192079.1 | 0 | 1 | 280 | 1 | 280 | chitinase, putative [Arabidopsis thaliana] |
| RefSeq | XP_002320933.1 | 0 | 26 | 279 | 1 | 249 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002515175.1 | 0 | 5 | 280 | 6 | 275 | class I chitinase, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3cql_B | 0 | 38 | 279 | 2 | 242 | A Chain A, Crystal Structure Of Gh Family 19 Chitinase From Carica Papaya |
| PDB | 3cql_A | 0 | 38 | 279 | 2 | 242 | A Chain A, Crystal Structure Of Gh Family 19 Chitinase From Carica Papaya |
| PDB | 4dyg_B | 0 | 38 | 280 | 3 | 244 | A Chain A, Crystal Structure Of Gh Family 19 Chitinase From Carica Papaya |
| PDB | 4dyg_A | 0 | 38 | 280 | 3 | 244 | A Chain A, Crystal Structure Of Gh Family 19 Chitinase From Carica Papaya |
| PDB | 4dwx_B | 0 | 38 | 280 | 3 | 244 | A Chain A, Crystal Structure Of A Family Gh-19 Chitinase From Rye Seeds |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| chitin degradation II | 3.2.1.14-RXN | EC-3.2.1.14 | chitinase |
| chitin degradation II | RXN-12623 | EC-3.2.1.14 | chitinase |
| chitin degradation II | RXN-12624 | EC-3.2.1.14 | chitinase |
| chitin degradation III (carnivorous plants) | 3.2.1.14-RXN | EC-3.2.1.14 | chitinase |
