| Basic Information | |
|---|---|
| Species | Arabidopsis thaliana |
| Cazyme ID | AT4G16745.2 |
| Family | GT47 |
| Protein Properties | Length: 590 Molecular Weight: 68253.8 Isoelectric Point: 10.4701 |
| Chromosome | Chromosome/Scaffold: 4 Start: 9411840 End: 9414897 |
| Description | exostosin family protein, putative, expressed |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 200 | 485 | 0 |
| LKVYIYPDGDKPIFHEPHLNGIYASEGWFMKLMESNKQFVTKNPERAHLFYMPYSVKQLQKSIFVPGSHNIKPLSIFLRDYVNMLSIKYPFWNRTHGSDH FLVACHDWGPYTVNEHPELKRNAIKALCNADLSDGIFVPGKDVSLPETSIRNAGRPLRNIGNGNRVSQRPILAFFAGNLHGRVRPKLLKHWRNKDEDMKI YGPLPHNVARKMTYVQHMKSSKYCLCPMGYEVNSPRIVEAIYYECVPVVIADNFMLPFSDVLDWSAFSVVVPEKEIPRLKEILLEI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 590 Download |
| MVNIKSPLRL FIEESIKELI RGFRRQRIKW RNAFLLGSIM TTIVVLLHTP TFSVFSDEEE 60 TESSSSSPIY LNGSLHLNIH IVSSEAKVEN FHTLRTRTPI VQLNASEASE AVLSRKRRKR 120 KKRKKTKDDL ILTDPPPAPR HVLSSSERRA LSLPPKKALT YAKLEIQRAP EVINDTDLFA 180 PLFRNLSVFK RSYELMELIL KVYIYPDGDK PIFHEPHLNG IYASEGWFMK LMESNKQFVT 240 KNPERAHLFY MPYSVKQLQK SIFVPGSHNI KPLSIFLRDY VNMLSIKYPF WNRTHGSDHF 300 LVACHDWGPY TVNEHPELKR NAIKALCNAD LSDGIFVPGK DVSLPETSIR NAGRPLRNIG 360 NGNRVSQRPI LAFFAGNLHG RVRPKLLKHW RNKDEDMKIY GPLPHNVARK MTYVQHMKSS 420 KYCLCPMGYE VNSPRIVEAI YYECVPVVIA DNFMLPFSDV LDWSAFSVVV PEKEIPRLKE 480 ILLEIPMRRY LKMQSNVKMV QRHFLWSPKP RKIKPFVKER ITILKLLLQP AVYHVWKKRN 540 ARIFTSIPSS VSTQCLAIDK TLRNRLLSFP SSDMRSSTTL LHFYFSCIS* 600 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 1.0e-68 | 200 | 485 | 302 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0003674 | molecular_function |
| GO:0008150 | biological_process |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CAB10449.1 | 0 | 24 | 516 | 512 | 998 | limonene cyclase like protein [Arabidopsis thaliana] |
| EMBL | CBI23466.1 | 0 | 27 | 516 | 15 | 518 | unnamed protein product [Vitis vinifera] |
| RefSeq | NP_567512.2 | 0 | 1 | 516 | 1 | 516 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_002269459.1 | 0 | 27 | 516 | 15 | 518 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002530666.1 | 0 | 67 | 516 | 54 | 508 | catalytic, putative [Ricinus communis] |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |
