| Basic Information | |
|---|---|
| Species | Arabidopsis thaliana |
| Cazyme ID | AT4G17770.1 |
| Family | GT20 |
| Protein Properties | Length: 863 Molecular Weight: 97454.5 Isoelectric Point: 6.0231 |
| Chromosome | Chromosome/Scaffold: 4 Start: 9876238 End: 9880254 |
| Description | trehalose synthase, putative, expressed |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT20 | 57 | 546 | 0 |
| VTQDRIIIVGNQLPIKSHRNSAGKLSFSWDNDSLLLQLKDGMREDMEVVYIGCLKEQIDTVEQDDVSQRLLENFKCVPAYIPPELFTKYYHGFCKQHLWP LFHYMLPLTPDLGGRFDRSLWQAYLSVNKIFADKVMEVISPDDDFVWVHDYHLMVLPTFLRKRFNRVKLGFFLHSPFPSSEIYRTLPVRNELLRALLNAD LIGFHTFDYARHFLSCCSRMLGLSYQSKRGTIGLEYYGRTVSIKILPVGIHISQLQSILNLPETQTKVAELRDQFLDQKVLLGVDDMDIFKGISLKLLAM EQLLTQHPEKRGRVVLVQIANPARGRGKDVQEVQSETEATVKRINEMFGRPGYQPVVLIDTPLQFFERIAYYVIAECCLVTAVRDGMNLIPYEYIICRQG NPKLNETIGLDPSAAKKSMLVVSEFIGCSPSLSGAIRVNPWNIDAVTEAMDYALIVSEAEKQMRHEKHHKYVSTHDVAYWARSFIQDLER | |||
| Full Sequence |
|---|
| Protein Sequence Length: 863 Download |
| MVSRSYSNLL DLASGNFHSF SREKKRFPRV ATVTGVLSEL DDDNNSNSVC SDAPSSVTQD 60 RIIIVGNQLP IKSHRNSAGK LSFSWDNDSL LLQLKDGMRE DMEVVYIGCL KEQIDTVEQD 120 DVSQRLLENF KCVPAYIPPE LFTKYYHGFC KQHLWPLFHY MLPLTPDLGG RFDRSLWQAY 180 LSVNKIFADK VMEVISPDDD FVWVHDYHLM VLPTFLRKRF NRVKLGFFLH SPFPSSEIYR 240 TLPVRNELLR ALLNADLIGF HTFDYARHFL SCCSRMLGLS YQSKRGTIGL EYYGRTVSIK 300 ILPVGIHISQ LQSILNLPET QTKVAELRDQ FLDQKVLLGV DDMDIFKGIS LKLLAMEQLL 360 TQHPEKRGRV VLVQIANPAR GRGKDVQEVQ SETEATVKRI NEMFGRPGYQ PVVLIDTPLQ 420 FFERIAYYVI AECCLVTAVR DGMNLIPYEY IICRQGNPKL NETIGLDPSA AKKSMLVVSE 480 FIGCSPSLSG AIRVNPWNID AVTEAMDYAL IVSEAEKQMR HEKHHKYVST HDVAYWARSF 540 IQDLERACGD HVRKRCWGIG FGLGFRVVAL DPSFKKLSIE HIVSAYKRTK NRAILLDYDG 600 TMVQPGSIRT TPTRETIEIL NNLSSDPKNI VYLVSGKDRR TLTEWFSSCD DLGLGAEHGY 660 FIRPNDGTDW ETSSLVSGFE WKQIAEPVMR LYTETTDGST IETKETALVW NYQFADPDFG 720 SCQAKELMEH LESVLTNDPV SVKTGQQLVE VKPQGVNKGL VAERLLTTMQ EKGKLLDFIL 780 CVGDDRSDED MFEVIMSAKD GPALSPVAEI FACTVGQKPS KAKYYLDDTA EIIRMLDGLA 840 ATNTTISDQT DSTATVPTKD LF* 900 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| PLN03063 | PLN03063 | 6.0e-172 | 61 | 849 | 823 | + alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional | ||
| PLN02205 | PLN02205 | 0 | 1 | 850 | 855 | + alpha,alpha-trehalose-phosphate synthase [UDP-forming] | ||
| pfam00982 | Glyco_transf_20 | 0 | 61 | 546 | 490 | + Glycosyltransferase family 20. Members of this family belong to glycosyl transferase family 20. OtsA (Trehalose-6-phosphate synthase) is homologous to regions in the subunits of yeast trehalose-6-phosphate synthase/phosphate complex. | ||
| cd03788 | GT1_TPS | 0 | 61 | 545 | 485 | + Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a nonreducing disaccharide present in a wide variety of organisms and may serve as a source of energy and carbon. It is characterized most notably in insect, plant, and microbial cells. Its production is often associated with a variety of stress conditions, including desiccation, dehydration, heat, cold, and oxidation. This family represents the catalytic domain of the TPS. Some members of this domain family coexist with a C-terminal trehalose phosphatase domain. | ||
| PRK14501 | PRK14501 | 0 | 61 | 841 | 797 | + putative bifunctional trehalose-6-phosphate synthase/HAD hydrolase subfamily IIB; Provisional | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0003824 | catalytic activity |
| GO:0004805 | trehalose-phosphatase activity |
| GO:0005992 | trehalose biosynthetic process |
| GO:0008152 | metabolic process |
| GO:0016757 | transferase activity, transferring glycosyl groups |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | ABD65165.1 | 0 | 1 | 862 | 1 | 857 | trehalose-6-phosphate synthase, putative [Brassica oleracea] |
| EMBL | CAB10557.1 | 0 | 1 | 862 | 18 | 865 | trehalose-6-phosphate synthase like protein [Arabidopsis thaliana] |
| EMBL | CAN61971.1 | 0 | 1 | 838 | 1 | 839 | hypothetical protein [Vitis vinifera] |
| RefSeq | NP_567538.1 | 0 | 1 | 862 | 1 | 862 | ATTPS5; protein binding / transferase, transferring glycosyl groups / trehalose-phosphatase [Arabidopsis thaliana] |
| RefSeq | XP_002304347.1 | 0 | 1 | 847 | 1 | 846 | predicted protein [Populus trichocarpa] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 2wtx_D | 0 | 144 | 546 | 75 | 453 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
| PDB | 2wtx_C | 0 | 144 | 546 | 75 | 453 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
| PDB | 2wtx_B | 0 | 144 | 546 | 75 | 453 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
| PDB | 2wtx_A | 0 | 144 | 546 | 75 | 453 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
| PDB | 1uqu_B | 0 | 144 | 546 | 75 | 453 | A Chain A, Trehalose-6-Phosphate From E. Coli Bound With Udp-Glucose. |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| HO777775 | 769 | 82 | 846 | 0 |
| HO779327 | 507 | 101 | 607 | 0 |
| HO779327 | 224 | 620 | 843 | 0 |
| HO797286 | 477 | 376 | 852 | 0 |
| HO777775 | 75 | 1 | 75 | 0.0000003 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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