y
Basic Information | |
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Species | Arabidopsis thaliana |
Cazyme ID | AT4G32790.1 |
Family | GT47 |
Protein Properties | Length: 594 Molecular Weight: 68632.1 Isoelectric Point: 8.5676 |
Chromosome | Chromosome/Scaffold: 4 Start: 15812095 End: 15814987 |
Description | exostosin family protein, putative, expressed |
View CDS |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 264 | 547 | 0 |
EKKLKVYVYREGKRPVLHKPVLKGIYASEGWFMKQLKSSRTFVTKDPRKAHLFYLPFSSKMLEETLYVPGSHSDKNLIQFLKNYLDMISSKYSFWNKTGG SDHFLVACHDWAPSETRQYMAKCIRALCNSDVSEGFVFGKDVALPETTILVPRRPLRALGGKPVSQRQILAFFAGGMHGYLRPLLLQNWGGNRDPDMKIF SEIPKSKGKKSYMEYMKSSKYCICPKGHEVNSPRVVEALFYECVPVIISDNFVPPFFEVLNWESFAVFVLEKDIPDLKNILVSI |
Full Sequence |
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Protein Sequence Length: 594 Download |
MLNLWLREHL VYVCHQQNLV AKFRSQKAMK LLRFAGLVFI FITTFQFVNI RYYGGDIFSL 60 SSQDKFPVSI DVSTEPVSTL SGPERLNSSS SRSVEVDEEE STGLKEDHVI GFDKNDTVQG 120 HDSFVEDVKD KETLDLLPGT KSSSNESYEK IVEDADIAFE NIRKMEILES KSDPSVDNLS 180 SEVKKFMNVS NSGVVSITEM MNLLHQSRTS HVSLKVKRSS TIDHELLYAR TQIENPPLIE 240 NDPLLHTPLY WNLSMFKRSY ELMEKKLKVY VYREGKRPVL HKPVLKGIYA SEGWFMKQLK 300 SSRTFVTKDP RKAHLFYLPF SSKMLEETLY VPGSHSDKNL IQFLKNYLDM ISSKYSFWNK 360 TGGSDHFLVA CHDWAPSETR QYMAKCIRAL CNSDVSEGFV FGKDVALPET TILVPRRPLR 420 ALGGKPVSQR QILAFFAGGM HGYLRPLLLQ NWGGNRDPDM KIFSEIPKSK GKKSYMEYMK 480 SSKYCICPKG HEVNSPRVVE ALFYECVPVI ISDNFVPPFF EVLNWESFAV FVLEKDIPDL 540 KNILVSITEE RYREMQMRVK MVQKHFLWHS KPERFDIFHM ILHSIWYNRV FQI* 600 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 8.0e-71 | 263 | 547 | 305 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0003824 | catalytic activity |
GO:0005739 | mitochondrion |
GO:0008150 | biological_process |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | NP_195005.1 | 0 | 1 | 593 | 1 | 593 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | NP_197954.1 | 0 | 30 | 593 | 15 | 652 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002281263.1 | 0 | 137 | 593 | 217 | 666 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002309547.1 | 0 | 150 | 593 | 20 | 468 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002324801.1 | 0 | 200 | 593 | 1 | 395 | predicted protein [Populus trichocarpa] |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |