| Basic Information | |
|---|---|
| Species | Arabidopsis thaliana |
| Cazyme ID | AT4G37520.2 |
| Family | AA2 |
| Protein Properties | Length: 327 Molecular Weight: 35749.8 Isoelectric Point: 8.78 |
| Chromosome | Chromosome/Scaffold: 4 Start: 17631657 End: 17633235 |
| Description | peroxidase precursor, putative, expressed |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| AA2 | 38 | 310 | 0 |
| NVEQIVRNAVQKKVQQTFTTIPATLRLYFHDCFVNGCDASVMIASTNNNKAEKDHEENLSLAGDGFDTVIKAKEALDAVPNCRNKVSCADILTMATRDVA GGPQYDVELGRLDGLSSTAASVGGKLPHPTDDVNKLTSLFAKNGLSLNDMIALSGAHTLGFAHCTKVFNRIYTFNKTTKVDPTVNKDYVTELKASCPRNI DPRVAINMDPTTPRQFDNVYYKNLQQGKGLFTSDQVLFTDRRSKPTVDLWANNGQLFNQAFINSMIKLGRVGV | |||
| Full Sequence |
|---|
| Protein Sequence Length: 327 Download |
| MVVVNKTNLL LLLLSLCLTL DLSSAQLRRN FYAGSCPNVE QIVRNAVQKK VQQTFTTIPA 60 TLRLYFHDCF VNGCDASVMI ASTNNNKAEK DHEENLSLAG DGFDTVIKAK EALDAVPNCR 120 NKVSCADILT MATRDVAGGP QYDVELGRLD GLSSTAASVG GKLPHPTDDV NKLTSLFAKN 180 GLSLNDMIAL SGAHTLGFAH CTKVFNRIYT FNKTTKVDPT VNKDYVTELK ASCPRNIDPR 240 VAINMDPTTP RQFDNVYYKN LQQGKGLFTS DQVLFTDRRS KPTVDLWANN GQLFNQAFIN 300 SMIKLGRVGV KTGSNGNIRR DCGAFN* 360 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam00141 | peroxidase | 2.0e-5 | 259 | 290 | 32 | + Peroxidase. | ||
| cd00314 | plant_peroxidase_like | 2.0e-22 | 41 | 307 | 300 | + Heme-dependent peroxidases similar to plant peroxidases. Along with animal peroxidases, these enzymes belong to a group of peroxidases containing a heme prosthetic group (ferriprotoporphyrin IX), which catalyzes a multistep oxidative reaction involving hydrogen peroxide as the electron acceptor. The plant peroxidase-like superfamily is found in all three kingdoms of life and carries out a variety of biosynthetic and degradative functions. Several sub-families can be identified. Class I includes intracellular peroxidases present in fungi, plants, archaea and bacteria, called catalase-peroxidases, that can exhibit both catalase and broad-spectrum peroxidase activities depending on the steady-state concentration of hydrogen peroxide. Catalase-peroxidases are typically comprised of two homologous domains that probably arose via a single gene duplication event. Class II includes ligninase and other extracellular fungal peroxidases, while class III is comprised of classic extracellular plant peroxidases, like horseradish peroxidase. | ||
| pfam00141 | peroxidase | 8.0e-53 | 43 | 195 | 156 | + Peroxidase. | ||
| PLN03030 | PLN03030 | 4.0e-68 | 28 | 326 | 307 | + cationic peroxidase; Provisional | ||
| cd00693 | secretory_peroxidase | 8.0e-158 | 26 | 325 | 303 | + Horseradish peroxidase and related secretory plant peroxidases. Secretory peroxidases belong to class III of the plant heme-dependent peroxidase superfamily. All members of the superfamily share a heme prosthetic group and catalyze a multistep oxidative reaction involving hydrogen peroxide as the electron acceptor. Class III peroxidases are found in the extracellular space or in the vacuole in plants where they have been implicated in hydrogen peroxide detoxification, auxin catabolism and lignin biosynthesis, and stress response. Class III peroxidases contain four conserved disulphide bridges and two conserved calcium binding sites. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004601 | peroxidase activity |
| GO:0005515 | protein binding |
| GO:0005737 | cytoplasm |
| GO:0006979 | response to oxidative stress |
| GO:0020037 | heme binding |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAL49862.1 | 0 | 1 | 326 | 1 | 329 | putative peroxidase [Arabidopsis thaliana] |
| GenBank | AAM63630.1 | 0 | 1 | 326 | 1 | 329 | peroxidase, prxr2 [Arabidopsis thaliana] |
| EMBL | CAA67362.1 | 0 | 18 | 326 | 1 | 312 | peroxidase ATP9a [Arabidopsis thaliana] |
| RefSeq | NP_195468.1 | 0 | 1 | 326 | 1 | 329 | peroxidase 50 (PER50) (P50) (PRXR2) [Arabidopsis thaliana] |
| RefSeq | NP_195469.1 | 0 | 1 | 326 | 1 | 329 | peroxidase, putative [Arabidopsis thaliana] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 1qo4_A | 0 | 26 | 326 | 2 | 304 | A Chain A, Heme Ligand Mutant Of Recombinant Horseradish Peroxidase In Complex With Benzhydroxamic Acid |
| PDB | 1pa2_A | 0 | 26 | 326 | 2 | 304 | A Chain A, Arabidopsis Thaliana Peroxidase A2 |
| PDB | 3hdl_A | 0 | 27 | 326 | 2 | 303 | A Chain A, Crystal Structure Of Highly Glycosylated Peroxidase From Royal Palm Tree |
| PDB | 3atj_B | 0 | 26 | 326 | 2 | 306 | A Chain A, Heme Ligand Mutant Of Recombinant Horseradish Peroxidase In Complex With Benzhydroxamic Acid |
| PDB | 3atj_A | 0 | 26 | 326 | 2 | 306 | A Chain A, Heme Ligand Mutant Of Recombinant Horseradish Peroxidase In Complex With Benzhydroxamic Acid |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| betanidin degradation | RXN-8635 | EC-1.11.1.7 | peroxidase |
