| Basic Information | |
|---|---|
| Species | Arabidopsis thaliana |
| Cazyme ID | AT4G38040.1 |
| Family | GT47 |
| Protein Properties | Length: 426 Molecular Weight: 48963 Isoelectric Point: 8.5834 |
| Chromosome | Chromosome/Scaffold: 4 Start: 17867438 End: 17869302 |
| Description | exostosin family domain containing protein, expressed |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 101 | 378 | 0 |
| EKRFKVYIYPDGDPNTFYQTPRKVTGKYASEGYFFQNIRESRFRTLDPDEADLFFIPISCHKMRGKGTSYENMTVIVQNYVDGLIAKYPYWNRTLGADHF FVTCHDVGVRAFEGSPLLIKNTIRVVCSPSYNVGFIPHKDVALPQVLQPFALPAGGNDVENRTTLGFWAGHRNSKIRVILAHVWENDTELDISNNRINRA TGHLVYQKRFYRTKFCICPGGSQVNSARITDSIHYGCIPVILSDYYDLPFNDILNWRKFAVVLREQDVYNLKQILKNI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 426 Download |
| MTIVKPSQFS FSGGGSSPLC SLKSSLLTVA ILTFISLFYL SLNSLRTSPP SPVIVVTPIH 60 VPHTFVNEYK TDNETPTMEE ETYSDVYHSP EAFRLNYAEM EKRFKVYIYP DGDPNTFYQT 120 PRKVTGKYAS EGYFFQNIRE SRFRTLDPDE ADLFFIPISC HKMRGKGTSY ENMTVIVQNY 180 VDGLIAKYPY WNRTLGADHF FVTCHDVGVR AFEGSPLLIK NTIRVVCSPS YNVGFIPHKD 240 VALPQVLQPF ALPAGGNDVE NRTTLGFWAG HRNSKIRVIL AHVWENDTEL DISNNRINRA 300 TGHLVYQKRF YRTKFCICPG GSQVNSARIT DSIHYGCIPV ILSDYYDLPF NDILNWRKFA 360 VVLREQDVYN LKQILKNIPH SEFVSLHNNL VKVQKHFQWN SPPVKFDAFH MIMYELWLRH 420 HVVKY* 480 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 3.0e-60 | 100 | 378 | 298 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0003824 | catalytic activity |
| GO:0008150 | biological_process |
| GO:0009507 | chloroplast |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| DDBJ | BAH56870.1 | 0 | 1 | 395 | 1 | 395 | AT4G38040 [Arabidopsis thaliana] |
| RefSeq | NP_195517.1 | 0 | 1 | 425 | 1 | 425 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_002266299.1 | 0 | 1 | 425 | 1 | 416 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002268836.1 | 0 | 19 | 425 | 12 | 417 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002307304.1 | 0 | 19 | 425 | 1 | 406 | predicted protein [Populus trichocarpa] |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |
| Hydropathy |
|---|
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| EG459159 | 264 | 163 | 426 | 0 |
| FY454337 | 307 | 28 | 334 | 0 |
| EH770778 | 275 | 116 | 390 | 0 |
| JG847451 | 284 | 66 | 349 | 0 |
| GO268625 | 269 | 100 | 368 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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