| Basic Information | |
|---|---|
| Species | Arabidopsis thaliana |
| Cazyme ID | AT5G03795.1 |
| Family | GT47 |
| Protein Properties | Length: 519 Molecular Weight: 58572.3 Isoelectric Point: 9.5015 |
| Chromosome | Chromosome/Scaffold: 5 Start: 1007390 End: 1010473 |
| Description | exostosin family protein, putative, expressed |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 187 | 468 | 0 |
| EKQFKIYVYKEGEPPLFHDGPCKSIYSMEGSFIYEIETDTRFRTNNPDKAHVFYLPFSVVKMVRYVYERNSRDFSPIRNTVKDYINLVGDKYPYWNRSIG ADHFILSCHDWGPEASFSHPHLGHNSIRALCNANTSERFKPRKDVSIPEINLRTGSLTGLVGGPSPSSRPILAFFAGGVHGPVRPVLLQHWENKDNDIRV HKYLPRGTSYSDMMRNSKFCICPSGYEVASPRIVEALYSGCVPVLINSGYVPPFSDVLNWRSFSVIVSVEDIPNLKTILTSI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 519 Download |
| MGDEDVDGKC KNMSACSSTT SYSTKLFLFM VPLVVISGFV FVNIGPKDST SLLTSLSTTT 60 SHLPPPFLST APAPAPSPLL PEILPSLPAS SLSTKVESIQ GDYNRTIQLN MINVTATSNN 120 VSSTASLEPK KRRVLSNLEK IEFKLQKARA SIKAASMDDP VDDPDYVPLG PMYWNAKVFH 180 RSYLEMEKQF KIYVYKEGEP PLFHDGPCKS IYSMEGSFIY EIETDTRFRT NNPDKAHVFY 240 LPFSVVKMVR YVYERNSRDF SPIRNTVKDY INLVGDKYPY WNRSIGADHF ILSCHDWGPE 300 ASFSHPHLGH NSIRALCNAN TSERFKPRKD VSIPEINLRT GSLTGLVGGP SPSSRPILAF 360 FAGGVHGPVR PVLLQHWENK DNDIRVHKYL PRGTSYSDMM RNSKFCICPS GYEVASPRIV 420 EALYSGCVPV LINSGYVPPF SDVLNWRSFS VIVSVEDIPN LKTILTSISP RQYLRMYRRV 480 LKVRRHFEVN SPAKRFDVFH MILHSIWVRR LNVKIREV* 540 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 6.0e-68 | 186 | 468 | 302 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| DDBJ | BAB08605.1 | 0 | 111 | 518 | 1 | 408 | unnamed protein product [Arabidopsis thaliana] |
| RefSeq | NP_001031828.1 | 0 | 1 | 518 | 1 | 518 | unknown protein [Arabidopsis thaliana] |
| RefSeq | XP_002284018.1 | 0 | 186 | 517 | 1 | 332 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002326234.1 | 0 | 186 | 513 | 1 | 328 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002528630.1 | 0 | 101 | 517 | 155 | 567 | catalytic, putative [Ricinus communis] |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |
