| Basic Information | |
|---|---|
| Species | Arabidopsis thaliana |
| Cazyme ID | AT5G11130.1 |
| Family | GT47 |
| Protein Properties | Length: 481 Molecular Weight: 55363.4 Isoelectric Point: 8.033 |
| Chromosome | Chromosome/Scaffold: 5 Start: 3542320 End: 3544724 |
| Description | exostosin family protein, putative, expressed |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 146 | 429 | 0 |
| EKRFKIWTYREGEAPLFHKGPLNNIYAIEGQFMDEIENGNSRFKAASPEEATVFYIPVGIVNIIRFVYRPYTSYARDRLQNIVKDYISLISNRYPYWNRS RGADHFFLSCHDWAPDVSAVDPELYKHFIRALCNANSSEGFTPMRDVSLPEINIPHSQLGFVHTGEPPQNRKLLAFFAGGSHGDVRKILFQHWKEKDKDV LVYENLPKTMNYTKMMDKAKFCLCPSGWEVASPRIVESLYSGCVPVIIADYYVLPFSDVLNWKTFSVHIPISKMPDIKKILEAI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 481 Download |
| MADLTCTTPF LLYPSLVIIL FFYSINHHNQ IFSSVVDDDP SCRLSSSPQA VFSSFRIFPF 60 RSSSSCLNIT SNNNSTSEVV VVEEVDEAVE RIEEGLAMAR AAIRKAGEKN LRRDRDRTNN 120 SDVGVVSNGS VYLNAFTFHQ SHKEMEKRFK IWTYREGEAP LFHKGPLNNI YAIEGQFMDE 180 IENGNSRFKA ASPEEATVFY IPVGIVNIIR FVYRPYTSYA RDRLQNIVKD YISLISNRYP 240 YWNRSRGADH FFLSCHDWAP DVSAVDPELY KHFIRALCNA NSSEGFTPMR DVSLPEINIP 300 HSQLGFVHTG EPPQNRKLLA FFAGGSHGDV RKILFQHWKE KDKDVLVYEN LPKTMNYTKM 360 MDKAKFCLCP SGWEVASPRI VESLYSGCVP VIIADYYVLP FSDVLNWKTF SVHIPISKMP 420 DIKKILEAIT EEEYLNMQRR VLEVRKHFVI NRPSKPYDML HMIMHSIWLR RLNVRIPLSQ 480 * 540 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 4.0e-70 | 145 | 429 | 303 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0003824 | catalytic activity |
| GO:0012505 | endomembrane system |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CBI21065.1 | 0 | 90 | 478 | 16 | 402 | unnamed protein product [Vitis vinifera] |
| EMBL | CBI25529.1 | 0 | 89 | 476 | 4 | 386 | unnamed protein product [Vitis vinifera] |
| RefSeq | NP_196674.1 | 0 | 145 | 480 | 1 | 336 | exostosin family protein [Arabidopsis thaliana] |
| Swiss-Prot | Q9LFP3 | 0 | 1 | 480 | 1 | 480 | GLYT4_ARATH RecName: Full=Probable glycosyltransferase At5g11130 |
| RefSeq | XP_002515488.1 | 0 | 1 | 476 | 12 | 468 | catalytic, putative [Ricinus communis] |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |
| Hydropathy |
|---|
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| EC939466 | 251 | 132 | 377 | 0 |
| EY926917 | 189 | 293 | 481 | 0 |
| EW739228 | 186 | 295 | 480 | 0 |
| GE475605 | 294 | 186 | 476 | 0 |
| EG631371 | 247 | 230 | 476 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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