| Basic Information | |
|---|---|
| Species | Arabidopsis thaliana |
| Cazyme ID | AT5G13000.1 |
| Family | GT48 |
| Protein Properties | Length: 1956 Molecular Weight: 226184 Isoelectric Point: 9.4064 |
| Chromosome | Chromosome/Scaffold: 5 Start: 4110295 End: 4121427 |
| Description | 1,3-beta-glucan synthase component domain containing protein, expressed |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
 | |||
| Family | Start | End | Evalue |
| GT48 | 1057 | 1810 | 0 |
| VPSNLEARRRISFFSNSLFMDMPMAPKVRNMLSFSVLTPYYTEEVLFSLRDLETPNEDGVSILFYLQKIFPDEWNNFLERVKCLSEEELKESDELEEELR LWASYRGQTLTRTVRGMMYYRKALELQAFLDMAMHEDLMEGYKAVELNSENNSRGERSLWAQCQAVADMKFTYVVSCQQYGIHKRSGDPRAQDILRLMTR YPSLRVAYIDEVEEPVKDKSKKGNQKVYYSVLVKVPKSTDHSTLAQNLDQVIYRIRLPGPAILGEGKPENQNHAIIFSRGEGLQTIDMNQDNYMEEALKM RNLLQEFLTKHDGVRHPSILGLREHIFTGSVSSLAWFMSNQETSFVTIGQRLLANPLRVRFHYGHPDVFDRLFHLTRGGVSKASKVINLSEDIFAGFNST LREGNVTHHEYIQVGKGRDVGLNQISMFEAKIANGNGEQTLSRDIYRLGHRFDFFRMMSCYFTTVGFYFSTLITVLTVYIFLYGRLYLVLSGLEQGLSTQ KGIRDNTPLQIALASQSFVQIGFLMALPMLMEIGLERGFRTALSEFVLMQLQLAPVFFTFSLGTKTHYYGRTLLHGGAKYRSTGRGFVVFHAKFADNYRL YSRSHFVKGLEMMLLLVVYQIFGSAYRGVLAYLLITISMWFMVGTWLFAPFLFNPSGFEWQKIVDDWTDWNKWINNIGGIGVPAEKSWESWWEEEQEHLR YSGKRGIVVEILLALRFFIYQYGLVYHLTITEKTKNFLVYGVSWLVIFLILFVM | |||
| Full Sequence |
|---|
| Protein Sequence Length: 1956 Download |
| MSATRGGPDQ GPSQPQQRRI IRTQTAGNLG ESFDSEVVPS SLVEIAPILR VANEVESSNP 60 RVAYLCRFYA FEKAHRLDPT SSGRGVRQFK TALLQRLERE HDPTLMGRVK KSDAREMQSF 120 YQHYYKKYIQ ALHNAADKAD RAQLTKAYQT ANVLFEVLKA VNLTQSIEVD REILEAQDKV 180 AEKTQLYVPY NILPLDPDSA NQAIMRYPEI QAAVLALRNT RGLPWPEGHK KKKDEDMLDW 240 LQEMFGFQKD NVANQREHLI LLLANVHIRQ FPKPDQQPKL DDQALTEVMK KLFKNYKKWC 300 KYLGRKSSLW LPTIQQEMQQ RKLLYMALYL LIWGEAANLR FMPECLCYIY HHMAFELYGM 360 LAGNVSPMTG ENVKPAYGGE EDAFLRKVVT PIYEVIQMEA QRSKKGKSKH SQWRNYDDLN 420 EYFWSVDCFR LGWPMRADAD FFCLPVAVPN TEKDGDNSKP IVARDRWVGK VNFVEIRSFW 480 HVFRSFDRMW SFYILCLQAM IIMAWDGGQP SSVFGADVFK KVLSVFITAA IMKLGQAVLD 540 VILNFKAHQS MTLHVKLRYI LKVFSAAAWV IILPVTYAYS WKDPPAFART IKSWFGSAMH 600 SPSLFIIAVV SYLSPNMLAG VMFLFPLLRR FLERSNYRIV MLMMWWSQPR LYVGRGMHES 660 AFSLFKYTMF WVLLIATKLA FSYYIEIRPL VAPTQAIMKA RVTNFQWHEF FPRAKNNIGV 720 VIALWAPIIL VYFMDSQIWY AIFSTLFGGI YGAFRRLGEI RTLGMLRSRF ESLPGAFNDR 780 LIPDGKNQQK KKGIRATLSH NFTEDKVPVN KEKEAARFAQ LWNTIISSFR EEDLISDREM 840 DLLLVPYWAD RDLDLIQWPP FLLASKIPIA LDMAKDSNGK DRELKKRIES DTYMKCAVRE 900 CYASFKNIIK FVVQGNREKE VIEIIFAEVD KHIDTGDLIQ EYKMSALPSL YDHFVKLIKY 960 LLDNKEEDRD HVVILFQDML EVVTRDIMME DYNISSLVDS SHGGTWHGGM IPLEQQYQLF 1020 ASSGAIRFPI EPVTEAWKEK IKRIYLLLTT KESAMDVPSN LEARRRISFF SNSLFMDMPM 1080 APKVRNMLSF SVLTPYYTEE VLFSLRDLET PNEDGVSILF YLQKIFPDEW NNFLERVKCL 1140 SEEELKESDE LEEELRLWAS YRGQTLTRTV RGMMYYRKAL ELQAFLDMAM HEDLMEGYKA 1200 VELNSENNSR GERSLWAQCQ AVADMKFTYV VSCQQYGIHK RSGDPRAQDI LRLMTRYPSL 1260 RVAYIDEVEE PVKDKSKKGN QKVYYSVLVK VPKSTDHSTL AQNLDQVIYR IRLPGPAILG 1320 EGKPENQNHA IIFSRGEGLQ TIDMNQDNYM EEALKMRNLL QEFLTKHDGV RHPSILGLRE 1380 HIFTGSVSSL AWFMSNQETS FVTIGQRLLA NPLRVRFHYG HPDVFDRLFH LTRGGVSKAS 1440 KVINLSEDIF AGFNSTLREG NVTHHEYIQV GKGRDVGLNQ ISMFEAKIAN GNGEQTLSRD 1500 IYRLGHRFDF FRMMSCYFTT VGFYFSTLIT VLTVYIFLYG RLYLVLSGLE QGLSTQKGIR 1560 DNTPLQIALA SQSFVQIGFL MALPMLMEIG LERGFRTALS EFVLMQLQLA PVFFTFSLGT 1620 KTHYYGRTLL HGGAKYRSTG RGFVVFHAKF ADNYRLYSRS HFVKGLEMML LLVVYQIFGS 1680 AYRGVLAYLL ITISMWFMVG TWLFAPFLFN PSGFEWQKIV DDWTDWNKWI NNIGGIGVPA 1740 EKSWESWWEE EQEHLRYSGK RGIVVEILLA LRFFIYQYGL VYHLTITEKT KNFLVYGVSW 1800 LVIFLILFVM KTVSVGRRRF SASFQLMFRL IKGLIFMTFI AIIVILITLA HMTIQDIIVC 1860 ILAFMPTGWG MLLIAQACKP VVHRAGFWGS VRTLARGYEI VMGLLLFTPV AFLAWFPFVS 1920 EFQTRMLFNQ AFSRGLQISR ILGGHRKDRS SRNKE* |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
 | ||||||||
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam04652 | DUF605 | 6.0e-11 | 45 | 159 | 124 | + Vta1 like. Vta1 (VPS20-associated protein 1) is a positive regulator of Vps4. Vps4 is an ATPase that is required in the multivesicular body (MVB) sorting pathway to dissociate the endosomal sorting complex required for transport (ESCRT). Vta1 promotes correct assembly of Vps4 and stimulates its ATPase activity through its conserved Vta1/SBP1/LIP5 region. | ||
| pfam14288 | FKS1_dom1 | 6.0e-58 | 320 | 436 | 118 | + 1,3-beta-glucan synthase subunit FKS1, domain-1. The FKS1_dom1 domain is likely to be the 'Class I' region just N-terminal to the first set of transmembrane helices that is involved in 1,3-beta-glucan synthesis itself. This family is found on proteins with family Glucan_synthase, pfam02364. | ||
| pfam02364 | Glucan_synthase | 0 | 1057 | 1807 | 819 | + 1,3-beta-glucan synthase component. This family consists of various 1,3-beta-glucan synthase components including Gls1, Gls2 and Gls3 from yeast. 1,3-beta-glucan synthase EC:2.4.1.34 also known as callose synthase catalyzes the formation of a beta-1,3-glucan polymer that is a major component of the fungal cell wall. The reaction catalyzed is:- UDP-glucose + {(1,3)-beta-D-glucosyl}(N) <=> UDP + {(1,3)-beta-D-glucosyl}(N+1). | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0000148 | 1,3-beta-D-glucan synthase complex |
| GO:0003843 | 1,3-beta-D-glucan synthase activity |
| GO:0005886 | plasma membrane |
| GO:0006075 | (1->3)-beta-D-glucan biosynthetic process |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CAB88264.1 | 0 | 1 | 1763 | 1 | 1807 | callose synthase catalytic subunit-like protein [Arabidopsis thaliana] |
| EMBL | CAB88264.1 | 7e-24 | 1875 | 1955 | 1883 | 1963 | callose synthase catalytic subunit-like protein [Arabidopsis thaliana] |
| RefSeq | NP_001154712.1 | 0 | 1 | 1955 | 1 | 1981 | ATGSL12 (glucan synthase-like 12); 1,3-beta-glucan synthase/ transferase, transferring glycosyl groups [Arabidopsis thaliana] |
| RefSeq | NP_196804.5 | 0 | 1 | 1955 | 1 | 1999 | ATGSL12 (glucan synthase-like 12); 1,3-beta-glucan synthase/ transferase, transferring glycosyl groups [Arabidopsis thaliana] |
| Swiss-Prot | Q9LXT9 | 0 | 1 | 1955 | 1 | 1964 | CALS3_ARATH RecName: Full=Callose synthase 3; AltName: Full=1,3-beta-glucan synthase; AltName: Full=Protein GLUCAN SYNTHASE-LIKE 12 |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 2lxm_A | 0.009 | 49 | 158 | 21 | 128 | B Chain B, Lip5-chmp5 |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| callose biosynthesis | 13-BETA-GLUCAN-SYNTHASE-RXN | EC-2.4.1.34 | 1,3-β-glucan synthase |
