| Basic Information | |
|---|---|
| Species | Arabidopsis thaliana |
| Cazyme ID | AT5G16890.1 |
| Family | GT47 |
| Protein Properties | Length: 512 Molecular Weight: 58080.6 Isoelectric Point: 9.6379 |
| Chromosome | Chromosome/Scaffold: 5 Start: 5551629 End: 5554917 |
| Description | exostosin family domain containing protein, expressed |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 118 | 427 | 0 |
| IKVYVYEMPKKFTFDLLWLFHNTYKETSNATSNGSPVHRLIEQHSIDYWLWADLISPESERRLKSVVRVQKQQDADFFYVPFFTTISFFLLEKQQCKALY REALKWVTDQPAWKRSEGRDHIFPIHHPWSFKSVRKFVKNAIWLLPDMDSTGNWYKPGQVSLEKDLILPYVPNVDICDTKCLSESAPMRTTLLFFRGRLK RNAGGKIRAKLGAELSGIKDIIISEGTAGEGGKLAAQRGMRRSLFCLCPAGDTPSSARLFDAIVSGCIPVIVSDELEFPFEGILDYKKVAVLVSSSDAIQ PGWLVNHLRS | |||
| Full Sequence |
|---|
| Protein Sequence Length: 512 Download |
| MSGKQQNHRS TSSRPRSKTL ILIGSLFTVS LLVILYTSSS SSRASISNPN PSDRPETSFV 60 TSLEHFLIYK APKLSLPVRD DTVRGESDDD VRKLDEMVFE RENRWLNEDP GYPVEFPIKV 120 YVYEMPKKFT FDLLWLFHNT YKETSNATSN GSPVHRLIEQ HSIDYWLWAD LISPESERRL 180 KSVVRVQKQQ DADFFYVPFF TTISFFLLEK QQCKALYREA LKWVTDQPAW KRSEGRDHIF 240 PIHHPWSFKS VRKFVKNAIW LLPDMDSTGN WYKPGQVSLE KDLILPYVPN VDICDTKCLS 300 ESAPMRTTLL FFRGRLKRNA GGKIRAKLGA ELSGIKDIII SEGTAGEGGK LAAQRGMRRS 360 LFCLCPAGDT PSSARLFDAI VSGCIPVIVS DELEFPFEGI LDYKKVAVLV SSSDAIQPGW 420 LVNHLRSLTP FQVKGLQNNL AQYSRHFLYS SPAQPLGPED LTWRMIAGKL VNIKLHTRRS 480 QRVVKGSRSI CRCDCWRSNS TASNSLSSLL S* 540 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 2.0e-64 | 117 | 427 | 319 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0003824 | catalytic activity |
| GO:0008150 | biological_process |
| GO:0009507 | chloroplast |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CBI20132.1 | 0 | 125 | 502 | 1 | 378 | unnamed protein product [Vitis vinifera] |
| RefSeq | NP_197191.1 | 0 | 1 | 511 | 1 | 511 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_002285599.1 | 0 | 55 | 502 | 62 | 512 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002325382.1 | 0 | 40 | 502 | 42 | 502 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002520033.1 | 0 | 48 | 502 | 49 | 503 | catalytic, putative [Ricinus communis] |
