| Basic Information | |
|---|---|
| Species | Arabidopsis thaliana |
| Cazyme ID | AT5G19670.1 |
| Family | GT47 |
| Protein Properties | Length: 611 Molecular Weight: 70381.1 Isoelectric Point: 10.02 |
| Chromosome | Chromosome/Scaffold: 5 Start: 6646719 End: 6649498 |
| Description | exostosin family protein, putative, expressed |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 279 | 561 | 0 |
| RILKVYVYKEGNRPIFHTPILKGLYASEGWFMKLMEGNKQYTVKDPRKAHLYYMPFSARMLEYTLYVRNSHNRTNLRQFLKEYTEHISSKYPFFNRTDGA DHFLVACHDWAPYETRHHMEHCIKALCNADVTAGFKIGRDISLPETYVRAAKNPLRDLGGKPPSQRRTLAFYAGSMHGYLRQILLQHWKDKDPDMKIFGR MPFGVASKMNYIEQMKSSKYCICPKGYEVNSPRVVESIFYECVPVIISDNFVPPFFEVLDWSAFSVIVAEKDIPRLKDILLSI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 611 Download |
| MEVRSELRKQ SRSGKRKWAI LVGIVALTHI LLLLSYGDAL RYLLPDGRRL KLPNENNALL 60 MTPSRNTLAV NVSEDSAVSG IHVLEKNGYV SGFGLRNESE DDEGFVGNVD FESFEDVKDS 120 IIIKEVAGSS DNLFPSETTV MQKESVSTSN NGYQVQNVTV QSQKNVKSSI LSGGSSIASP 180 ASGNSSLLVS KKVSKKKKMR CDLPPKSVTT IDEMNRILAR HRRTSRAMRP RWSSRRDEEI 240 LTARKEIENA PVAKLERELY PPIFRNVSLF KRSYELMERI LKVYVYKEGN RPIFHTPILK 300 GLYASEGWFM KLMEGNKQYT VKDPRKAHLY YMPFSARMLE YTLYVRNSHN RTNLRQFLKE 360 YTEHISSKYP FFNRTDGADH FLVACHDWAP YETRHHMEHC IKALCNADVT AGFKIGRDIS 420 LPETYVRAAK NPLRDLGGKP PSQRRTLAFY AGSMHGYLRQ ILLQHWKDKD PDMKIFGRMP 480 FGVASKMNYI EQMKSSKYCI CPKGYEVNSP RVVESIFYEC VPVIISDNFV PPFFEVLDWS 540 AFSVIVAEKD IPRLKDILLS IPEDKYVKMQ MAVRKAQRHF LWHAKPEKYD LFHMVLHSIW 600 YNRVFQAKRR * 660 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 4.0e-66 | 281 | 561 | 301 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0003824 | catalytic activity |
| GO:0008150 | biological_process |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CAN76867.1 | 0 | 1 | 607 | 710 | 1391 | hypothetical protein [Vitis vinifera] |
| EMBL | CAN76867.1 | 0 | 155 | 606 | 219 | 709 | hypothetical protein [Vitis vinifera] |
| RefSeq | NP_197468.1 | 0 | 1 | 610 | 1 | 600 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_002283936.1 | 0 | 203 | 610 | 1 | 410 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002514248.1 | 0 | 36 | 610 | 39 | 676 | catalytic, putative [Ricinus communis] |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |
