| Basic Information | |
|---|---|
| Species | Arabidopsis thaliana |
| Cazyme ID | AT5G20260.1 |
| Family | GT47 |
| Protein Properties | Length: 459 Molecular Weight: 52272.4 Isoelectric Point: 9.5989 |
| Chromosome | Chromosome/Scaffold: 5 Start: 6836806 End: 6839532 |
| Description | exostosin family protein, putative, expressed |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 126 | 410 | 0 |
| EKKFKVWVYREGETPLVHMGPMNNIYSIEGQFMDEIETGMSPFAANNPEEAHAFLLPVSVANIVHYLYRPLVTYSREQLHKVFLDYVDVVAHKYPYWNRS LGADHFYVSCHDWAPDVSGSNPELMKNLIRVLCNANTSEGFMPQRDVSIPEINIPGGHLGPPRLSRSSGHDRPILAFFAGGSHGYIRRILLQHWKDKDEE VQVHEYLAKNKDYFKLMATARFCLCPSGYEVASPRVVAAINLGCVPVIISDHYALPFSDVLDWTKFTIHVPSKKIPEIKTILKSI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 459 Download |
| MKLSLVPTLL LLLVLLVFYQ HHSSPNLNSN ALSSFVDATS LAPSPSPSLS MEFSVASSNL 60 STISSPPENK GNKRNIIEEG LAKSRSAIRE AVRLKKFVSD KEETFVPRGA VYRNAFAFHQ 120 SHIEMEKKFK VWVYREGETP LVHMGPMNNI YSIEGQFMDE IETGMSPFAA NNPEEAHAFL 180 LPVSVANIVH YLYRPLVTYS REQLHKVFLD YVDVVAHKYP YWNRSLGADH FYVSCHDWAP 240 DVSGSNPELM KNLIRVLCNA NTSEGFMPQR DVSIPEINIP GGHLGPPRLS RSSGHDRPIL 300 AFFAGGSHGY IRRILLQHWK DKDEEVQVHE YLAKNKDYFK LMATARFCLC PSGYEVASPR 360 VVAAINLGCV PVIISDHYAL PFSDVLDWTK FTIHVPSKKI PEIKTILKSI SWRRYRVLQR 420 RVLQVQRHFV INRPSQPFDM LRMLLHSVWL RRLNLRLP* 480 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 1.0e-66 | 125 | 410 | 304 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0003824 | catalytic activity |
| GO:0008150 | biological_process |
| GO:0012505 | endomembrane system |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CBI25529.1 | 0 | 77 | 457 | 7 | 386 | unnamed protein product [Vitis vinifera] |
| RefSeq | NP_197526.4 | 0 | 51 | 458 | 1 | 408 | catalytic [Arabidopsis thaliana] |
| Swiss-Prot | Q3E9A4 | 0 | 1 | 458 | 9 | 466 | GLYT5_ARATH RecName: Full=Probable glycosyltransferase At5g20260 |
| RefSeq | XP_002324625.1 | 0 | 125 | 458 | 1 | 334 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002531945.1 | 0 | 5 | 458 | 13 | 451 | catalytic, putative [Ricinus communis] |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |
