| Basic Information | |
|---|---|
| Species | Arabidopsis thaliana |
| Cazyme ID | AT5G22940.1 |
| Family | GT47 |
| Protein Properties | Length: 470 Molecular Weight: 53808.9 Isoelectric Point: 9.8736 |
| Chromosome | Chromosome/Scaffold: 5 Start: 7676938 End: 7679179 |
| Description | exostosin family domain containing protein, expressed |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 108 | 407 | 0 |
| GMKIYVYDLPASYNDDWVTASDRCASHLFAAEVAIHRALLSSDVRTLDPDEADYFFVPVYVSCNFSTSNGFPSLSHARSLLSSAVDFLSDHYPFWNRSQG SDHVFVASHDFGACFHAMEDMAIEEGIPKFMKRSIILQTFGVKYKHPCQEVEHVVIPPYIPPESVQKAIEKAPVNGRRDIWAFFRGKMEVNPKNISGRFY SKGVRTAILKKFGGRRRFYLNRHRFAGYRSEIVRSVFCLCPLGWAPWSPRLVESAVLGCVPVVIADGIQLPFSETVQWPEISLTVAEKDVRNLRKVLEHV | |||
| Full Sequence |
|---|
| Protein Sequence Length: 470 Download |
| MSLDIKKPNI TKTKKKKTGF VVKMQLNNNR GGNKRNIFIF FFFRNYYTWI LWFCLSLYFF 60 TSYFSVEDQS SPSSIRLLSN HKTSSSLPSR ALIESSAIKT TSIGLFTGMK IYVYDLPASY 120 NDDWVTASDR CASHLFAAEV AIHRALLSSD VRTLDPDEAD YFFVPVYVSC NFSTSNGFPS 180 LSHARSLLSS AVDFLSDHYP FWNRSQGSDH VFVASHDFGA CFHAMEDMAI EEGIPKFMKR 240 SIILQTFGVK YKHPCQEVEH VVIPPYIPPE SVQKAIEKAP VNGRRDIWAF FRGKMEVNPK 300 NISGRFYSKG VRTAILKKFG GRRRFYLNRH RFAGYRSEIV RSVFCLCPLG WAPWSPRLVE 360 SAVLGCVPVV IADGIQLPFS ETVQWPEISL TVAEKDVRNL RKVLEHVAAT NLSAIQRNLH 420 EPVFKRALLY NVPMKEGDAT WHILESLWRK LDDRSYRRSR VLSQREVDM* 480 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 1.0e-72 | 108 | 404 | 304 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0003824 | catalytic activity |
| GO:0005794 | Golgi apparatus |
| GO:0010417 | glucuronoxylan biosynthetic process |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | ABI64067.1 | 0 | 46 | 464 | 23 | 442 | glycosyltransferase GT47C [Populus tremula x Populus alba] |
| DDBJ | BAB10615.1 | 0 | 1 | 469 | 1 | 498 | unnamed protein product [Arabidopsis thaliana] |
| RefSeq | NP_197685.2 | 0 | 1 | 469 | 1 | 469 | F8H (FRA8 HOMOLOG); catalytic [Arabidopsis thaliana] |
| RefSeq | XP_002275679.1 | 0 | 16 | 452 | 9 | 441 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002314302.1 | 0 | 1 | 464 | 1 | 462 | predicted protein [Populus trichocarpa] |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |
