| Basic Information | |
|---|---|
| Species | Arabidopsis thaliana |
| Cazyme ID | AT5G24090.1 |
| Family | GH18 |
| Protein Properties | Length: 303 Molecular Weight: 33096.5 Isoelectric Point: 9.2746 |
| Chromosome | Chromosome/Scaffold: 5 Start: 8143699 End: 8145252 |
| Description | glycosyl hydrolase, putative, expressed |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GH18 | 32 | 250 | 4.3e-26 |
| IAIYWGQNGNEGNLSATCATGRYAYVNVAFLVKFGNGQTPELNLAGHCNPAANTCTHFGSQVKDCQSRGIKVMLSLGGGIGNYSIGSREDAKVIADYLWN NFLGGKSSSRPLGDAVLDGIDFNIELGSPQHWDDLARTLSKFSHRGRKIYLTGAPQCPFPDRLMGSALNTKRFDYVWIQFYNNPPCSYSSGNTQNLFDSW NKWTTSIAAQKFFLGLPAA | |||
| Full Sequence |
|---|
| Protein Sequence Length: 303 Download |
| MTNMTLRKHV IYFLFFISCS LSKPSDASRG GIAIYWGQNG NEGNLSATCA TGRYAYVNVA 60 FLVKFGNGQT PELNLAGHCN PAANTCTHFG SQVKDCQSRG IKVMLSLGGG IGNYSIGSRE 120 DAKVIADYLW NNFLGGKSSS RPLGDAVLDG IDFNIELGSP QHWDDLARTL SKFSHRGRKI 180 YLTGAPQCPF PDRLMGSALN TKRFDYVWIQ FYNNPPCSYS SGNTQNLFDS WNKWTTSIAA 240 QKFFLGLPAA PEAAGSGYIP PDVLTSQILP TLKKSRKYGG VMLWSKFWDD KNGYSSSILA 300 SV* 360 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| cd06546 | GH18_CTS3_chitinase | 0.0004 | 97 | 287 | 215 | + GH18 domain of CTS3 (chitinase 3), an uncharacterized protein from the human fungal pathogen Coccidioides posadasii. CTS3 has a chitinase-like glycosyl hydrolase family 18 (GH18) domain; and has homologs in bacteria as well as fungi. | ||
| COG3469 | COG3469 | 2.0e-12 | 54 | 290 | 275 | + Chitinase [Carbohydrate transport and metabolism] | ||
| cd02871 | GH18_chitinase_D-like | 2.0e-14 | 54 | 297 | 295 | + GH18 domain of Chitinase D (ChiD). ChiD, a chitinase found in Bacillus circulans, hydrolyzes the 1,4-beta-linkages of N-acetylglucosamine in chitin and chitodextrins. The domain architecture of ChiD includes a catalytic glycosyl hydrolase family 18 (GH18) domain, a chitin-binding domain, and a fibronectin type III domain. The chitin-binding and fibronectin type III domains are located either N-terminal or C-terminal to the catalytic domain. This family includes exochitinase Chi36 from Bacillus cereus. | ||
| pfam00704 | Glyco_hydro_18 | 6.0e-28 | 30 | 289 | 335 | + Glycosyl hydrolases family 18. | ||
| cd02877 | GH18_hevamine_XipI_class_III | 2.0e-132 | 30 | 298 | 278 | + This conserved domain family includes xylanase inhibitor Xip-I, and the class III plant chitinases such as hevamine, concanavalin B, and PPL2, all of which have a glycosyl hydrolase family 18 (GH18) domain. Hevamine is a class III endochitinase that hydrolyzes the linear polysaccharide chains of chitin and peptidoglycan and is important for defense against pathogenic bacteria and fungi. PPL2 (Parkia platycephala lectin 2) is a class III chitinase from Parkia platycephala seeds that hydrolyzes beta(1-4) glycosidic bonds linking 2-acetoamido-2-deoxy-beta-D-glucopyranose units in chitin. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0003824 | catalytic activity |
| GO:0004553 | hydrolase activity, hydrolyzing O-glycosyl compounds |
| GO:0005975 | carbohydrate metabolic process |
| GO:0009409 | response to cold |
| GO:0009611 | response to wounding |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| DDBJ | BAA21860.1 | 0 | 1 | 302 | 1 | 302 | acidic endochitinase [Arabidopsis thaliana] |
| DDBJ | BAA21863.1 | 0 | 1 | 302 | 1 | 302 | acidic endochitinase [Arabidopsis thaliana] |
| DDBJ | BAA21865.1 | 0 | 1 | 302 | 1 | 302 | acidic endochitinase [Arabidopsis thaliana] |
| DDBJ | BAA21870.1 | 0 | 1 | 302 | 1 | 302 | acidic endochitinase [Arabidopsis thaliana] |
| RefSeq | NP_197797.1 | 0 | 1 | 302 | 1 | 302 | acidic endochitinase (CHIB1) [Arabidopsis thaliana] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 2hvm_A | 0 | 30 | 302 | 1 | 273 | A Chain A, Pectin Methylesterase From Yersinia Enterocolitica |
| PDB | 1llo_A | 0 | 30 | 302 | 1 | 273 | A Chain A, Pectin Methylesterase From Yersinia Enterocolitica |
| PDB | 1hvq_A | 0 | 30 | 302 | 1 | 273 | A Chain A, Crystal Structures Of Hevamine, A Plant Defence Protein With Chitinase And Lysozyme Activity, And Its Complex With An Inhibitor |
| PDB | 1kr0_A | 0 | 30 | 302 | 1 | 273 | A Chain A, Hevamine Mutant D125aY183F IN COMPLEX WITH TETRA-Nag |
| PDB | 1kr1_A | 0 | 30 | 302 | 1 | 273 | A Chain A, Hevamine Mutant D125aE127A IN COMPLEX WITH TETRA-Nag |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| chitin degradation II | 3.2.1.14-RXN | EC-3.2.1.14 | chitinase |
| chitin degradation II | RXN-12623 | EC-3.2.1.14 | chitinase |
| chitin degradation II | RXN-12624 | EC-3.2.1.14 | chitinase |
| chitin degradation III (carnivorous plants) | 3.2.1.14-RXN | EC-3.2.1.14 | chitinase |
