| Basic Information | |
|---|---|
| Species | Arabidopsis thaliana |
| Cazyme ID | AT5G33290.1 |
| Family | GT47 |
| Protein Properties | Length: 501 Molecular Weight: 56600.1 Isoelectric Point: 9.9836 |
| Chromosome | Chromosome/Scaffold: 5 Start: 12558256 End: 12562020 |
| Description | exostosin family protein, putative, expressed |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 162 | 451 | 0 |
| NRFKVWTYTEGEVPLFHDGPVNDIYGIEGQFMDEMCVDGPKSRSRFRADRPENAHVFFIPFSVAKVIHFVYKPITSVEGFSRARLHRLIEDYVDVVATKH PYWNRSQGGDHFMVSCHDWAPDVIDGNPKLFEKFIRGLCNANTSEGFRPNVDVSIPEIYLPKGKLGPSFLGKSPRVRSILAFFAGRSHGEIRKILFQHWK EMDNEVQVYDRLPPGKDYTKTMGMSKFCLCPSGWEVASPREVEAIYAGCVPVIISDNYSLPFSDVLNWDSFSIQIPVSRIKEIKTILQSV | |||
| Full Sequence |
|---|
| Protein Sequence Length: 501 Download |
| MAAPRSRRCS LSLLTLFSIT LILISVSLFV STKPANKPFL DYRNQFSISI SISSPLEQNT 60 TNTSFVSASP PLSPLGQSNT TNTILASSSS SSSFSDHQNQ NKSPSPTSKK IVIRKRSGLD 120 KIESDLAKAR AAIKKAASTQ NYVSSLYKNP AAFHQSHTEM MNRFKVWTYT EGEVPLFHDG 180 PVNDIYGIEG QFMDEMCVDG PKSRSRFRAD RPENAHVFFI PFSVAKVIHF VYKPITSVEG 240 FSRARLHRLI EDYVDVVATK HPYWNRSQGG DHFMVSCHDW APDVIDGNPK LFEKFIRGLC 300 NANTSEGFRP NVDVSIPEIY LPKGKLGPSF LGKSPRVRSI LAFFAGRSHG EIRKILFQHW 360 KEMDNEVQVY DRLPPGKDYT KTMGMSKFCL CPSGWEVASP REVEAIYAGC VPVIISDNYS 420 LPFSDVLNWD SFSIQIPVSR IKEIKTILQS VSLVRYLKMY KRVLEVKQHF VLNRPAKPYD 480 VMHMMLHSIW LRRLNLRLGT * 540 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 4.0e-64 | 160 | 451 | 311 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0003824 | catalytic activity |
| GO:0005794 | Golgi apparatus |
| GO:0010398 | xylogalacturonan metabolic process |
| GO:0016020 | membrane |
| GO:0035252 | UDP-xylosyltransferase activity |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAK83577.1 | 0 | 160 | 500 | 1 | 341 | AT5g33290/F19N2_10 [Arabidopsis thaliana] |
| GenBank | ABA18105.1 | 0 | 114 | 498 | 27 | 421 | exostosin family protein [Capsella rubella] |
| GenBank | ABG48476.1 | 0 | 108 | 498 | 22 | 423 | At3g42180 [Arabidopsis thaliana] |
| RefSeq | NP_189804.4 | 0 | 108 | 498 | 67 | 468 | catalytic/ transferase, transferring glycosyl groups [Arabidopsis thaliana] |
| RefSeq | NP_198314.2 | 0 | 1 | 500 | 1 | 500 | XGD1 (XYLOGALACTURONAN DEFICIENT 1); UDP-xylosyltransferase/ catalytic [Arabidopsis thaliana] |
