| Basic Information | |
|---|---|
| Species | Arabidopsis thaliana |
| Cazyme ID | AT5G41250.1 |
| Family | GT47 |
| Protein Properties | Length: 562 Molecular Weight: 65207.6 Isoelectric Point: 8.7222 |
| Chromosome | Chromosome/Scaffold: 5 Start: 16501217 End: 16502902 |
| Description | exostosin family domain containing protein, expressed |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 176 | 507 | 0 |
| SCEGKGVYVYDLPSKFNSDLLVGCNDILPGVNLCSYFKNEGFGEAIKNLGKGWFATHMYSLEPILHSRVLKHPCRVYNETQAKLFFVPYYGGYDVLRWHY RNVSEDVKDRLGIEVLKWLNSKESWRRNAGKDHVFVLGKITWDFRRDKDPWGSRFLELQEMQNPTKLLIERQPWQVNDIAIPHPTYFHPRTDDDITRWQI KIMSKLRRNLVSFAGGARPDNPNNIRSTLIEQCISSNQCRFLNCTNESCTNPKNVLDLFQDSEFCLQPPGDSATRRSVFDSLISGCIPVIFTPYTAYYQY AWHLPEDHRKYSVYISEQDVKEKRVNVVEILK | |||
| Full Sequence |
|---|
| Protein Sequence Length: 562 Download |
| MVSKRKSRTS KTIEDSCIHL CSVFFRFLYY TLPALFLFFF LLYLCLSFTT GISYNNFHMC 60 IFSRKFNDPY CNTAGSKPGF QIISEENVTF AGEIAGDRVS KDHNKILNSV PVQEHKTKNK 120 VDLNSLIELK AEEEYSKYIK PTSEDEGYAL RAAIKYLYLQ RSWLSPGDEN LNKPRSCEGK 180 GVYVYDLPSK FNSDLLVGCN DILPGVNLCS YFKNEGFGEA IKNLGKGWFA THMYSLEPIL 240 HSRVLKHPCR VYNETQAKLF FVPYYGGYDV LRWHYRNVSE DVKDRLGIEV LKWLNSKESW 300 RRNAGKDHVF VLGKITWDFR RDKDPWGSRF LELQEMQNPT KLLIERQPWQ VNDIAIPHPT 360 YFHPRTDDDI TRWQIKIMSK LRRNLVSFAG GARPDNPNNI RSTLIEQCIS SNQCRFLNCT 420 NESCTNPKNV LDLFQDSEFC LQPPGDSATR RSVFDSLISG CIPVIFTPYT AYYQYAWHLP 480 EDHRKYSVYI SEQDVKEKRV NVVEILKAKT LKEKKDMKSY IVQQLLPGLV YGDSNAKFEK 540 FRDAFDITFD CLLKKINRSV V* 600 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 2.0e-74 | 176 | 508 | 348 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0003824 | catalytic activity |
| GO:0008150 | biological_process |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | NP_176534.2 | 0 | 2 | 560 | 28 | 664 | catalytic [Arabidopsis thaliana] |
| RefSeq | NP_198941.1 | 0 | 1 | 561 | 1 | 561 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_002269913.1 | 0 | 55 | 558 | 58 | 536 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002299537.1 | 0 | 58 | 558 | 61 | 571 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002509789.1 | 0 | 55 | 558 | 58 | 565 | Xyloglucan galactosyltransferase KATAMARI1, putative [Ricinus communis] |
