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Basic Information | |
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Species | Arabidopsis thaliana |
Cazyme ID | AT5G44360.1 |
Family | AA7 |
Protein Properties | Length: 533 Molecular Weight: 60498.7 Isoelectric Point: 9.7846 |
Chromosome | Chromosome/Scaffold: 5 Start: 17871924 End: 17873698 |
Description | berberine and berberine like domain containing protein, expressed |
View CDS |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
AA7 | 78 | 527 | 0 |
NFTSQKPILIVTPRTDTEIQRSLLCSRKLGVKVRTKSGGHDYEGLSYLSLHSPFIILDLVNVRSIEINLADETAWVGAGATIGELYYKIAKSSKIHGFPA GTCPSVGVGGHFSGGGFGAMMRKHGLAADNVVDARFVDANGRIYNSRREMGEDLFWAIRGGGAASFGVVLSWKVKLVRVPEKVTCFRRNLPLTQNMTKIV HRWQQIAAELDDNLFIRVIVSISGGSVQTTFQANYLGGIDKLIPLMNQKFPELGLTFQDCSEMTWIDSIMYFNWKKGQPLETLLDRGQRYNDLYFKAKSD FVKNPIPEIGLEGIWTRFHEVESPIMIMEPLGGKMYEIGETETPFPHRRGNLYNIQYMVKWRLKDIGVMEKHVTWMRLLYRYMRVYVSASPRGAYLNYRD LDLGMNRGVNTSFEDAKLWGFRYFGSNFKRLAIVKGKIDPTNFFRNEQSV |
Full Sequence |
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Protein Sequence Length: 533 Download |
MRTLEAFALS LFLVFLVKWV NSDSSSSPSK DQFLSCMSTH SDSSFINPKS FIHKPDSRVY 60 TDFSQSLISQ NYRFLTLNFT SQKPILIVTP RTDTEIQRSL LCSRKLGVKV RTKSGGHDYE 120 GLSYLSLHSP FIILDLVNVR SIEINLADET AWVGAGATIG ELYYKIAKSS KIHGFPAGTC 180 PSVGVGGHFS GGGFGAMMRK HGLAADNVVD ARFVDANGRI YNSRREMGED LFWAIRGGGA 240 ASFGVVLSWK VKLVRVPEKV TCFRRNLPLT QNMTKIVHRW QQIAAELDDN LFIRVIVSIS 300 GGSVQTTFQA NYLGGIDKLI PLMNQKFPEL GLTFQDCSEM TWIDSIMYFN WKKGQPLETL 360 LDRGQRYNDL YFKAKSDFVK NPIPEIGLEG IWTRFHEVES PIMIMEPLGG KMYEIGETET 420 PFPHRRGNLY NIQYMVKWRL KDIGVMEKHV TWMRLLYRYM RVYVSASPRG AYLNYRDLDL 480 GMNRGVNTSF EDAKLWGFRY FGSNFKRLAI VKGKIDPTNF FRNEQSVPPL IV* 540 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
COG0277 | GlcD | 7.0e-13 | 82 | 530 | 476 | + FAD/FMN-containing dehydrogenases [Energy production and conversion] | ||
pfam08031 | BBE | 5.0e-17 | 471 | 528 | 58 | + Berberine and berberine like. This domain is found in the berberine bridge and berberine bridge- like enzymes which are involved in the biosynthesis of numerous isoquinoline alkaloids. They catalyze the transformation of the N-methyl group of (S)-reticuline into the C-8 berberine bridge carbon of (S)-scoulerine. | ||
pfam01565 | FAD_binding_4 | 5.0e-19 | 84 | 222 | 140 | + FAD binding domain. This family consists of various enzymes that use FAD as a co-factor, most of the enzymes are similar to oxygen oxidoreductase. One of the enzymes Vanillyl-alcohol oxidase (VAO) has a solved structure, the alignment includes the FAD binding site, called the PP-loop, between residues 99-110. The FAD molecule is covalently bound in the known structure, however the residue that links to the FAD is not in the alignment. VAO catalyzes the oxidation of a wide variety of substrates, ranging form aromatic amines to 4-alkylphenols. Other members of this family include D-lactate dehydrogenase, this enzyme catalyzes the conversion of D-lactate to pyruvate using FAD as a co-factor; mitomycin radical oxidase, this enzyme oxidises the reduced form of mitomycins and is involved in mitomycin resistance. This family includes MurB an UDP-N-acetylenolpyruvoylglucosamine reductase enzyme EC:1.1.1.158. This enzyme is involved in the biosynthesis of peptidoglycan. |
Gene Ontology | |
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GO Term | Description |
GO:0003824 | catalytic activity |
GO:0008762 | UDP-N-acetylmuramate dehydrogenase activity |
GO:0009055 | electron carrier activity |
GO:0012505 | endomembrane system |
GO:0016491 | oxidoreductase activity |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAK56258.1 | 0 | 26 | 530 | 22 | 529 | AF367269_1 AT4g20860/T13K14_20 [Arabidopsis thaliana] |
GenBank | AAN60251.1 | 0 | 5 | 454 | 3 | 451 | unknown [Arabidopsis thaliana] |
RefSeq | NP_193818.1 | 0 | 26 | 530 | 22 | 529 | FAD-binding domain-containing protein [Arabidopsis thaliana] |
RefSeq | NP_199249.1 | 0 | 1 | 532 | 1 | 532 | FAD-binding domain-containing protein [Arabidopsis thaliana] |
RefSeq | XP_002267029.1 | 0 | 6 | 530 | 248 | 770 | PREDICTED: hypothetical protein [Vitis vinifera] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 3vte_A | 0 | 30 | 530 | 4 | 513 | A Chain A, Crystal Structure Of Tetrahydrocannabinolic Acid Synthase From Cannabis Sativa |
PDB | 4dns_B | 0 | 33 | 531 | 13 | 497 | A Chain A, Crystal Structure Of Bermuda Grass Isoallergen Bg60 Provides Insight Into The Various Cross-Allergenicity Of The Pollen Group 4 Allergens |
PDB | 4dns_A | 0 | 33 | 531 | 13 | 497 | A Chain A, Crystal Structure Of Bermuda Grass Isoallergen Bg60 Provides Insight Into The Various Cross-Allergenicity Of The Pollen Group 4 Allergens |
PDB | 3tsj_B | 0 | 29 | 531 | 7 | 497 | A Chain A, Crystal Structure Of Bermuda Grass Isoallergen Bg60 Provides Insight Into The Various Cross-Allergenicity Of The Pollen Group 4 Allergens |
PDB | 3tsj_A | 0 | 29 | 531 | 7 | 497 | A Chain A, Crystal Structure Of Bermuda Grass Isoallergen Bg60 Provides Insight Into The Various Cross-Allergenicity Of The Pollen Group 4 Allergens |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
cannabinoid biosynthesis | RXN-7854 | EC-1.21.3 | tetrahydrocannabinolic acid synthase |