Basic Information | |
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Species | Arabidopsis thaliana |
Cazyme ID | AT5G44400.1 |
Family | AA7 |
Protein Properties | Length: 538 Molecular Weight: 60345.3 Isoelectric Point: 10.2141 |
Chromosome | Chromosome/Scaffold: 5 Start: 17886194 End: 17888480 |
Description | berberine and berberine like domain containing protein, expressed |
View CDS |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
AA7 | 82 | 304 | 0 |
PKPGFIFSPIHESHVQASIICSKKLRMHLRVRSGGHDYEGLSYVSQIDKPFILMDLSKMRQVNINIQDNSAWVQSGATVGELYYRIAEKSKVHGFPAGLC SSLGIGGHITGGAYGSMMRKYGLGADNVLDAKIVDANGKLLDRAAMGEDTFWAIRGGAGGSFGIILAWKIKLVPVPKTVTVFTVTKTLQQDVGNKIISKW QRVADKLVEELFIRVLFNVAGTG |
Full Sequence |
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Protein Sequence Length: 538 Download |
MGISKPLPLF SILVLYFSLY TITPTSSLAS LQDQFINCVQ RNTHVYFPLE KTFFAPTKNV 60 SMFSQVLEST AQNLRFLKKS MPKPGFIFSP IHESHVQASI ICSKKLRMHL RVRSGGHDYE 120 GLSYVSQIDK PFILMDLSKM RQVNINIQDN SAWVQSGATV GELYYRIAEK SKVHGFPAGL 180 CSSLGIGGHI TGGAYGSMMR KYGLGADNVL DAKIVDANGK LLDRAAMGED TFWAIRGGAG 240 GSFGIILAWK IKLVPVPKTV TVFTVTKTLQ QDVGNKIISK WQRVADKLVE ELFIRVLFNV 300 AGTGGNKTVT TSYNALFLGG KGTLMNVMKK SFPELGLTFK DCIEMSWLES IAYISGFPTH 360 TPTNVLLQGK SPFPKVSFKA KSDFVKTPIP ESGLQGIFKK LLKEDIPLMI WNPYGGMMAK 420 IPESQIPFPH RKGVLFKVQY VTSWLDSDKR PSRHINWIRD LYSYMTPYVS SNPREAYVNY 480 RDLDLGRNTK DVKTCIKQAQ VWGANYFKNN FNRLMMIKAK VDPENFFRHE QSIPPMM* 540 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
COG0277 | GlcD | 2.0e-14 | 84 | 253 | 180 | + FAD/FMN-containing dehydrogenases [Energy production and conversion] | ||
pfam01565 | FAD_binding_4 | 8.0e-19 | 84 | 223 | 141 | + FAD binding domain. This family consists of various enzymes that use FAD as a co-factor, most of the enzymes are similar to oxygen oxidoreductase. One of the enzymes Vanillyl-alcohol oxidase (VAO) has a solved structure, the alignment includes the FAD binding site, called the PP-loop, between residues 99-110. The FAD molecule is covalently bound in the known structure, however the residue that links to the FAD is not in the alignment. VAO catalyzes the oxidation of a wide variety of substrates, ranging form aromatic amines to 4-alkylphenols. Other members of this family include D-lactate dehydrogenase, this enzyme catalyzes the conversion of D-lactate to pyruvate using FAD as a co-factor; mitomycin radical oxidase, this enzyme oxidises the reduced form of mitomycins and is involved in mitomycin resistance. This family includes MurB an UDP-N-acetylenolpyruvoylglucosamine reductase enzyme EC:1.1.1.158. This enzyme is involved in the biosynthesis of peptidoglycan. | ||
pfam08031 | BBE | 3.0e-19 | 476 | 534 | 59 | + Berberine and berberine like. This domain is found in the berberine bridge and berberine bridge- like enzymes which are involved in the biosynthesis of numerous isoquinoline alkaloids. They catalyze the transformation of the N-methyl group of (S)-reticuline into the C-8 berberine bridge carbon of (S)-scoulerine. |
Gene Ontology | |
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GO Term | Description |
GO:0003824 | catalytic activity |
GO:0005618 | cell wall |
GO:0008762 | UDP-N-acetylmuramate dehydrogenase activity |
GO:0009055 | electron carrier activity |
GO:0016491 | oxidoreductase activity |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAL24314.1 | 0 | 1 | 536 | 1 | 540 | berberine bridge enzyme-like protein [Arabidopsis thaliana] |
RefSeq | NP_199251.1 | 0 | 1 | 536 | 1 | 539 | FAD-binding domain-containing protein [Arabidopsis thaliana] |
RefSeq | NP_199252.1 | 0 | 1 | 536 | 1 | 540 | FAD-binding domain-containing protein [Arabidopsis thaliana] |
RefSeq | NP_199253.1 | 0 | 1 | 537 | 1 | 537 | FAD-binding domain-containing protein [Arabidopsis thaliana] |
RefSeq | XP_002268361.1 | 0 | 10 | 536 | 6 | 527 | PREDICTED: hypothetical protein [Vitis vinifera] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 3vte_A | 0 | 29 | 536 | 1 | 513 | A Chain A, Crystal Structure Of Tetrahydrocannabinolic Acid Synthase From Cannabis Sativa |
PDB | 4dns_B | 0 | 23 | 537 | 1 | 497 | A Chain A, Crystal Structure Of Bermuda Grass Isoallergen Bg60 Provides Insight Into The Various Cross-Allergenicity Of The Pollen Group 4 Allergens |
PDB | 4dns_A | 0 | 23 | 537 | 1 | 497 | A Chain A, Crystal Structure Of Bermuda Grass Isoallergen Bg60 Provides Insight Into The Various Cross-Allergenicity Of The Pollen Group 4 Allergens |
PDB | 3tsj_B | 0 | 57 | 537 | 26 | 497 | A Chain A, Crystal Structure Of Bermuda Grass Isoallergen Bg60 Provides Insight Into The Various Cross-Allergenicity Of The Pollen Group 4 Allergens |
PDB | 3tsj_A | 0 | 57 | 537 | 26 | 497 | A Chain A, Crystal Structure Of Bermuda Grass Isoallergen Bg60 Provides Insight Into The Various Cross-Allergenicity Of The Pollen Group 4 Allergens |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
cannabinoid biosynthesis | RXN-7854 | EC-1.21.3 | tetrahydrocannabinolic acid synthase |