| Basic Information | |
|---|---|
| Species | Arabidopsis thaliana |
| Cazyme ID | AT5G44440.1 |
| Family | AA7 |
| Protein Properties | Length: 534 Molecular Weight: 60136.7 Isoelectric Point: 7.8979 |
| Chromosome | Chromosome/Scaffold: 5 Start: 17910557 End: 17912312 |
| Description | reticuline oxidase-like protein precursor, putative, expressed |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| AA7 | 76 | 526 | 0 |
| PKPVSIITPVKASDVQTVIRCAQLHGIHVRTRSAGHCYEGLSYIAYNKPFAVIDLRNLRSISLDVDNRTGWVQTGATAGELYYEIGKTTKSLAFPAGIHP TVGVGGQFSGGGYGTLLRKYGLAADNIIDALVVDASGRILDRQAMGEDYFWAIRGGGGSSFGVILSWKVKLVDVPSTITVFKVQKTSKKEAVRIIKKWQY AADKVPDDLFIRTTLERSNKNAVHALFTGLYIGPVNNLLALMEEKFPELGLEKEGCEEMSWIESVLWFADFPKGESLGVLTNRERTSLSFKGKDDFVQEP IPEAAIQEIWRRLEAPEARLGKIILTPFGGKMSEMAEYETPFPHRGGNLYEIQYVAYWREEEDKNKTETDKYLKWVDSVYEFMTPYVSKSPRGAYVNFKD MDLGMYLGKKKTKYEEGKSWGVKYFKNNFERLVRVKTRVDPTDFFCDEQSI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 534 Download |
| MEFSSFLFTI LLFSLNISPL VSAHGSNHED FLKCLSYRMN DNTVEPKVIH TSKDSSFFSI 60 LDSSIQNPRF SVSETPKPVS IITPVKASDV QTVIRCAQLH GIHVRTRSAG HCYEGLSYIA 120 YNKPFAVIDL RNLRSISLDV DNRTGWVQTG ATAGELYYEI GKTTKSLAFP AGIHPTVGVG 180 GQFSGGGYGT LLRKYGLAAD NIIDALVVDA SGRILDRQAM GEDYFWAIRG GGGSSFGVIL 240 SWKVKLVDVP STITVFKVQK TSKKEAVRII KKWQYAADKV PDDLFIRTTL ERSNKNAVHA 300 LFTGLYIGPV NNLLALMEEK FPELGLEKEG CEEMSWIESV LWFADFPKGE SLGVLTNRER 360 TSLSFKGKDD FVQEPIPEAA IQEIWRRLEA PEARLGKIIL TPFGGKMSEM AEYETPFPHR 420 GGNLYEIQYV AYWREEEDKN KTETDKYLKW VDSVYEFMTP YVSKSPRGAY VNFKDMDLGM 480 YLGKKKTKYE EGKSWGVKYF KNNFERLVRV KTRVDPTDFF CDEQSIPLVN KVT* 540 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam08031 | BBE | 1.0e-15 | 469 | 527 | 59 | + Berberine and berberine like. This domain is found in the berberine bridge and berberine bridge- like enzymes which are involved in the biosynthesis of numerous isoquinoline alkaloids. They catalyze the transformation of the N-methyl group of (S)-reticuline into the C-8 berberine bridge carbon of (S)-scoulerine. | ||
| COG0277 | GlcD | 9.0e-17 | 78 | 255 | 185 | + FAD/FMN-containing dehydrogenases [Energy production and conversion] | ||
| pfam01565 | FAD_binding_4 | 1.0e-17 | 78 | 216 | 142 | + FAD binding domain. This family consists of various enzymes that use FAD as a co-factor, most of the enzymes are similar to oxygen oxidoreductase. One of the enzymes Vanillyl-alcohol oxidase (VAO) has a solved structure, the alignment includes the FAD binding site, called the PP-loop, between residues 99-110. The FAD molecule is covalently bound in the known structure, however the residue that links to the FAD is not in the alignment. VAO catalyzes the oxidation of a wide variety of substrates, ranging form aromatic amines to 4-alkylphenols. Other members of this family include D-lactate dehydrogenase, this enzyme catalyzes the conversion of D-lactate to pyruvate using FAD as a co-factor; mitomycin radical oxidase, this enzyme oxidises the reduced form of mitomycins and is involved in mitomycin resistance. This family includes MurB an UDP-N-acetylenolpyruvoylglucosamine reductase enzyme EC:1.1.1.158. This enzyme is involved in the biosynthesis of peptidoglycan. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0003824 | catalytic activity |
| GO:0008762 | UDP-N-acetylmuramate dehydrogenase activity |
| GO:0009055 | electron carrier activity |
| GO:0012505 | endomembrane system |
| GO:0016491 | oxidoreductase activity |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAO29955.1 | 0 | 39 | 533 | 1 | 495 | berberine bridge enzyme-like protein [Arabidopsis thaliana] |
| DDBJ | BAE99575.1 | 0 | 19 | 533 | 3 | 511 | berberine bridge enzyme-like protein [Arabidopsis thaliana] |
| RefSeq | NP_193814.1 | 0 | 1 | 527 | 1 | 524 | FAD-binding domain-containing protein [Arabidopsis thaliana] |
| RefSeq | NP_199254.1 | 0 | 1 | 533 | 1 | 533 | FAD-binding domain-containing protein [Arabidopsis thaliana] |
| RefSeq | NP_199257.1 | 0 | 1 | 533 | 1 | 533 | FAD-binding domain-containing protein [Arabidopsis thaliana] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3vte_A | 0 | 29 | 527 | 5 | 511 | A Chain A, Crystal Structure Of Tetrahydrocannabinolic Acid Synthase From Cannabis Sativa |
| PDB | 4dns_B | 0 | 28 | 527 | 10 | 494 | A Chain A, Crystal Structure Of Bermuda Grass Isoallergen Bg60 Provides Insight Into The Various Cross-Allergenicity Of The Pollen Group 4 Allergens |
| PDB | 4dns_A | 0 | 28 | 527 | 10 | 494 | A Chain A, Crystal Structure Of Bermuda Grass Isoallergen Bg60 Provides Insight Into The Various Cross-Allergenicity Of The Pollen Group 4 Allergens |
| PDB | 3tsj_B | 0 | 29 | 531 | 9 | 498 | A Chain A, Crystal Structure Of Bermuda Grass Isoallergen Bg60 Provides Insight Into The Various Cross-Allergenicity Of The Pollen Group 4 Allergens |
| PDB | 3tsj_A | 0 | 29 | 531 | 9 | 498 | A Chain A, Crystal Structure Of Bermuda Grass Isoallergen Bg60 Provides Insight Into The Various Cross-Allergenicity Of The Pollen Group 4 Allergens |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| cannabinoid biosynthesis | RXN-7854 | EC-1.21.3 | tetrahydrocannabinolic acid synthase |
