| Basic Information | |
|---|---|
| Species | Arabidopsis thaliana |
| Cazyme ID | AT5G50420.1 |
| Family | GT68 |
| Protein Properties | Length: 567 Molecular Weight: 64410.5 Isoelectric Point: 7.1501 |
| Chromosome | Chromosome/Scaffold: 5 Start: 20530206 End: 20532856 |
| Description | GDP-fucose protein-O-fucosyltransferase 2, putative, expressed |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT68 | 246 | 544 | 0 |
| DRVLVIPSSKFDYQYDRVIDIERINTCLGRNVVVAFDQFKEKAKKNHFRIDRFICYFSSPQLCYVDEEHIKKLKGLGISIDGKLEAPWSEDIKKPSKRTV QDVQMKFKSDDDVIAIGDVFYADMEQDWVMQPGGPINHKCKTLIEPSKLILLTAQRFIQTFLGKNFIALHFRRHGFLKFCNAKSPSCFYPIPQAAECIAR IVERSNGAVIYLSTDAAESETSLLQSLVVVDGKIVPLVKRPPRNSAEKWDALLYRHGIEDDSQVDAMLDKTICAMSSVFIGASGSTFTEDILRLRKDWG | |||
| Full Sequence |
|---|
| Protein Sequence Length: 567 Download |
| MERNSSDDEE DHQHLIPQND TRIRHREDSV SSNATTIGGN QRSAFQIDDI LHRVQHRGKI 60 SLNKRYVIVF VSLIISIGLL FLLTDPRELF AANFSSFKLD PLSNRVKESE LRALYLLRQQ 120 QLALLSLWNG TLVNPSLNQS ENALGSSVLF EDVKSAVSKQ ISLNKEIQEV LLSPHRSSNY 180 SGGTDVDSVN FSYNRCRKVD QKLSDRKTVE WKPRSDKFLF AICLSGQMSN HLICLEKHMF 240 FAALLDRVLV IPSSKFDYQY DRVIDIERIN TCLGRNVVVA FDQFKEKAKK NHFRIDRFIC 300 YFSSPQLCYV DEEHIKKLKG LGISIDGKLE APWSEDIKKP SKRTVQDVQM KFKSDDDVIA 360 IGDVFYADME QDWVMQPGGP INHKCKTLIE PSKLILLTAQ RFIQTFLGKN FIALHFRRHG 420 FLKFCNAKSP SCFYPIPQAA ECIARIVERS NGAVIYLSTD AAESETSLLQ SLVVVDGKIV 480 PLVKRPPRNS AEKWDALLYR HGIEDDSQVD AMLDKTICAM SSVFIGASGS TFTEDILRLR 540 KDWGTSSTCD EYLCRGEEPN FIAEDE* 600 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| cd11296 | O-FucT_like | 0.0005 | 218 | 252 | 35 | + GDP-fucose protein O-fucosyltransferase and related proteins. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes. | ||
| pfam10250 | O-FucT | 9.0e-6 | 241 | 533 | 330 | + GDP-fucose protein O-fucosyltransferase. This is a family of conserved proteins representing the enzyme responsible for adding O-fucose to EGF (epidermal growth factor-like) repeats. Six highly conserved cysteines are present in O-FucT-1 as well as a DXD-like motif (ERD), conserved in mammals, Drosophila, and C. elegans. Both features are characteristic of several glycosyltransferase families. The enzyme is a membrane-bound protein released by proteolysis and, as for most glycosyltransferases, is strongly activated by manganese. | ||
| cd11548 | NodZ_like | 3.0e-6 | 347 | 541 | 198 | + Alpha 1,6-fucosyltransferase similar to Bradyrhizobium NodZ. Bradyrhizobium NodZ is an alpha 1,6-fucosyltransferase involved in the biosynthesis of the nodulation factor, a lipo-chitooligosaccharide formed by three-to-six beta-1,4-linked N-acetyl-d-glucosamine (GlcNAc) residues and a fatty acid acyl group attached to the nitrogen atom at the non-reducing end. NodZ transfers L-fucose from the GDP-beta-L-fucose donor to the reducing residue of the chitin oligosaccharide backbone, before the attachment of a fatty acid group. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes. | ||
| cd11298 | O-FucT-2 | 2.0e-9 | 407 | 533 | 127 | + GDP-fucose protein O-fucosyltransferase 2. O-FucT-2 adds O-fucose to thrombospondin type 1 repeats (TSRs), and appears conserved in bilateria. The O-fucosylation of TSRs appears to play a role in regulating secretion of metalloproteases of the ADAMTS superfamily. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes. | ||
| cd11296 | O-FucT_like | 8.0e-18 | 382 | 540 | 169 | + GDP-fucose protein O-fucosyltransferase and related proteins. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0003674 | molecular_function |
| GO:0005575 | cellular_component |
| GO:0008150 | biological_process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAD50008.1 | 0 | 1 | 566 | 1 | 594 | AC007651_3 Hypothetical Protein [Arabidopsis thaliana] |
| GenBank | AAM66093.1 | 0 | 1 | 566 | 1 | 566 | unknown [Arabidopsis thaliana] |
| RefSeq | NP_173170.2 | 0 | 1 | 566 | 1 | 564 | unknown protein [Arabidopsis thaliana] |
| RefSeq | NP_199853.1 | 0 | 1 | 566 | 1 | 566 | unknown protein [Arabidopsis thaliana] |
| RefSeq | XP_002264087.1 | 0 | 1 | 566 | 1 | 559 | PREDICTED: hypothetical protein [Vitis vinifera] |
