Basic Information | |
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Species | Arabidopsis thaliana |
Cazyme ID | AT5G61840.1 |
Family | GT47 |
Protein Properties | Length: 416 Molecular Weight: 47194.6 Isoelectric Point: 7.208 |
Chromosome | Chromosome/Scaffold: 5 Start: 24839178 End: 24841940 |
Description | exostosin family domain containing protein, expressed |
View CDS |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 48 | 343 | 0 |
RLKVFVYELPSKYNKKILQKDPRCLNHMFAAEIYMQRFLLSSPVRTLNPEEADWFYVPVYTTCDLTPNGLPLPFKSPRMMRSAIQLIASNWPYWNRTEGA DHFFVVPHDFGACFHYQEEKAIGRGILPLLQRATLVQTFGQRNHVCLKEGSITVPPYAPPQKMQSHLIPEKTPRSIFVYFRGLFYDVGNDPEGGYYARGA RAAVWENFKDNPLFDISTEHPTTYYEDMQRAIFCLCPLGWAPWSPRLVEAVIFGCIPVIIADDIVLPFADAIPWEDIGVFVDEKDVPYLDTILTSI |
Full Sequence |
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Protein Sequence Length: 416 Download |
MKLSSCVLIF LLCNTFSSIS AFRLSRSQPT ERISGSAGDV LEDDPVGRLK VFVYELPSKY 60 NKKILQKDPR CLNHMFAAEI YMQRFLLSSP VRTLNPEEAD WFYVPVYTTC DLTPNGLPLP 120 FKSPRMMRSA IQLIASNWPY WNRTEGADHF FVVPHDFGAC FHYQEEKAIG RGILPLLQRA 180 TLVQTFGQRN HVCLKEGSIT VPPYAPPQKM QSHLIPEKTP RSIFVYFRGL FYDVGNDPEG 240 GYYARGARAA VWENFKDNPL FDISTEHPTT YYEDMQRAIF CLCPLGWAPW SPRLVEAVIF 300 GCIPVIIADD IVLPFADAIP WEDIGVFVDE KDVPYLDTIL TSIPPEVILR KQRLLANPSM 360 KQAMLFPQPA QPGDAFHQVL NGLARKLPHE RSVYLRPGEK LLNWTAGPVA DLKPW* 420 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-79 | 48 | 343 | 304 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0003824 | catalytic activity |
GO:0005794 | Golgi apparatus |
GO:0009834 | secondary cell wall biogenesis |
GO:0010417 | glucuronoxylan biosynthetic process |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAM64940.1 | 0 | 1 | 415 | 1 | 415 | unknown [Arabidopsis thaliana] |
RefSeq | NP_568941.1 | 0 | 1 | 415 | 1 | 415 | GUT1; catalytic/ glucuronoxylan glucuronosyltransferase [Arabidopsis thaliana] |
RefSeq | XP_002284685.1 | 0 | 6 | 415 | 9 | 416 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002318180.1 | 0 | 18 | 415 | 20 | 417 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002511079.1 | 0 | 9 | 415 | 11 | 417 | catalytic, putative [Ricinus communis] |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |