| Basic Information | |
|---|---|
| Species | Arabidopsis thaliana |
| Cazyme ID | AT5G62220.1 |
| Family | GT47 |
| Protein Properties | Length: 518 Molecular Weight: 59645.5 Isoelectric Point: 8.42 |
| Chromosome | Chromosome/Scaffold: 5 Start: 24988456 End: 24990009 |
| Description | exostosin family domain containing protein, expressed |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 118 | 460 | 0 |
| CDSGRVFVYDMPKIFNEVILQQCDNLNPWSSRCDALSNDGFGQEATSLSNVIPKDLVQSWFWTDQFVTEIIFHNRILNHRCRTLDPESATAFYIPFYAGL AVGQYLWSNYAAADRDRHCKMMTQWVKNQPYWNRSNGWDHFITMGRITWDFRRSKDEDWGSNCIYIPGMRNITRLLIERNSWDHFDVGVPYPTGFHPRSD SDVVNWQDFVRNRRRETLFCFAGAPRAGIVNDFRGLLLRHCEESRGKCRTVDCTVGKCSNGSSAILETFLGSDFCLQPRGDSFTRRSIFDCMLAGSIPVF FWRRSAYMQYQWFLPDKPDSYSVFIDRNEVTNGTTSIKEVLER | |||
| Full Sequence |
|---|
| Protein Sequence Length: 518 Download |
| MLPVSNPSSP EHLLKKSRTP DSTTSIDRKN SFNSLHSVGN RSSYIAASRS HCTWLILSLL 60 SLQLILFLTL RSIPFPHRHI PENFPSPAAV VTTTVTTTVI SAASSNPPLS SSSSDERCDS 120 GRVFVYDMPK IFNEVILQQC DNLNPWSSRC DALSNDGFGQ EATSLSNVIP KDLVQSWFWT 180 DQFVTEIIFH NRILNHRCRT LDPESATAFY IPFYAGLAVG QYLWSNYAAA DRDRHCKMMT 240 QWVKNQPYWN RSNGWDHFIT MGRITWDFRR SKDEDWGSNC IYIPGMRNIT RLLIERNSWD 300 HFDVGVPYPT GFHPRSDSDV VNWQDFVRNR RRETLFCFAG APRAGIVNDF RGLLLRHCEE 360 SRGKCRTVDC TVGKCSNGSS AILETFLGSD FCLQPRGDSF TRRSIFDCML AGSIPVFFWR 420 RSAYMQYQWF LPDKPDSYSV FIDRNEVTNG TTSIKEVLER YSKEDVRKMR ERVIDLIPNL 480 VYAKSPNGLE TFKDAFDVAI DGVFRRFKEQ EKWYKWR* 540 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 6.0e-60 | 117 | 461 | 360 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0003824 | catalytic activity |
| GO:0009507 | chloroplast |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| DDBJ | BAA97186.1 | 0 | 1 | 515 | 1 | 515 | unnamed protein product [Arabidopsis thaliana] |
| RefSeq | NP_201028.1 | 0 | 1 | 517 | 1 | 517 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_002270309.1 | 0 | 1 | 516 | 1 | 489 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002318866.1 | 0 | 1 | 516 | 1 | 512 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002510893.1 | 0 | 1 | 516 | 1 | 497 | Xyloglucan galactosyltransferase KATAMARI1, putative [Ricinus communis] |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| DY290373 | 373 | 128 | 499 | 0 |
| BU238022 | 260 | 259 | 518 | 0 |
| DY267021 | 343 | 157 | 499 | 0 |
| EX091911 | 261 | 229 | 489 | 0 |
| BU238022 | 20 | 243 | 262 | 0.099 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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