Basic Information | |
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Species | Aquilegia coerulea |
Cazyme ID | Aquca_001_00330.1 |
Family | GT47 |
Protein Properties | Length: 628 Molecular Weight: 71559.8 Isoelectric Point: 8.0444 |
Chromosome | Chromosome/Scaffold: 1 Start: 3468170 End: 3471873 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 299 | 581 | 0 |
LLKIYIYREGEKPIFHEPTEPILKGIYASEGWFMKQMERNKQFVVEDPTKAHLFYLPISSRMLQLQLYIRNSHNRQNLADYMKNYVDMITTKYPFWNRTG GADHFIVACHDWAPFETRGHMDNCIKVLCNANIARDFKIGKDVALPTTQMRKVKDPLRGLGGNPASERPILAFFAGGMHGSLRPVLLQYWGNQDPDMKIF GQMPQGTTMSYIQHMKSSKYCICARGFDVHTPRVVEAIFHECVPVIISDDYVPPFFEVLDWEAFAVFVPEKDIPSLKNILLSI |
Full Sequence |
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Protein Sequence Length: 628 Download |
MDRLLHFQKL CQLDTRRLLL VIGVVFSAIL VFQSSALPSR NVFWSLFSSR RIPLSERSST 60 LSRDSTPKSE MVGNSTFLNE LSSSESSFTK SSFENIFHDN NLTNGNVRSS DNGYTLEKTR 120 EPETSSSIEQ VKQPNNNLSY ENVRNEDTSL TVEMIGSKSG SNASAPDANA SIAIISVIPN 180 TSSVGVQAPE MFPKDEKPFA QQSGLITSNA STAVTGSYVM SKDWESDTPI SKLNTLLLQS 240 KDSVHSMRPL WSSKCDHELL SARSQINNAP IIKNDLELYP SIYRNVSMFK RSYKLMEQLL 300 KIYIYREGEK PIFHEPTEPI LKGIYASEGW FMKQMERNKQ FVVEDPTKAH LFYLPISSRM 360 LQLQLYIRNS HNRQNLADYM KNYVDMITTK YPFWNRTGGA DHFIVACHDW APFETRGHMD 420 NCIKVLCNAN IARDFKIGKD VALPTTQMRK VKDPLRGLGG NPASERPILA FFAGGMHGSL 480 RPVLLQYWGN QDPDMKIFGQ MPQGTTMSYI QHMKSSKYCI CARGFDVHTP RVVEAIFHEC 540 VPVIISDDYV PPFFEVLDWE AFAVFVPEKD IPSLKNILLS IPEEKYFEMQ TGVKRVQKHF 600 LWHIEPVKYD IFHMILHSVW LHRLNQV* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 6.0e-66 | 300 | 581 | 299 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CBI28021.1 | 0 | 1 | 627 | 1 | 662 | unnamed protein product [Vitis vinifera] |
RefSeq | XP_002280595.1 | 0 | 7 | 627 | 5 | 660 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002281263.1 | 0 | 7 | 627 | 5 | 666 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002283936.1 | 0 | 225 | 627 | 4 | 407 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002516500.1 | 0 | 230 | 626 | 58 | 452 | catalytic, putative [Ricinus communis] |