Basic Information | |
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Species | Aquilegia coerulea |
Cazyme ID | Aquca_001_00331.1 |
Family | GT47 |
Protein Properties | Length: 635 Molecular Weight: 72804.2 Isoelectric Point: 8.5712 |
Chromosome | Chromosome/Scaffold: 1 Start: 3472162 End: 3476455 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 310 | 586 | 0 |
NMLKIYIYNEGDKPIFHHPNLKGIYASEGWFMKLLERNKQFVVKNPLEAHMFYLPFSSLVLRKTLIQPHWVLAEYLKNYVELIAGKYRFWNRTGGADHFL VACHDWALEETKKYMGTCIRALCNTDAARSFKIGKDVSLPVTYIRFEDNPVRSLGGKPPSKRPFLAFFAGSMHGHVRPILLRHWENKDPDMKIFGRLPPS EKPSYVQYMKSSKYCICAKGYEVHTPRVVEAIFHECVPVIISDNYVPPFFEVLKWETFSVFILEKDIPNLKNVLLSI |
Full Sequence |
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Protein Sequence Length: 635 Download |
MVCAPQFQKL YKIETKRLIL VVGILFPIIV VLLSSSLSLP YGDVLQSLLS FKSVMVRQSN 60 VVHNSNSTSS SMVNDTEVII NQENEIRVQD KDPNNDDQLE EEEEDQTSDF ESDKTVNETS 120 TVGSAEFEDN TKSDHSSSSL TSRNITNSEA NFVSEPLFVS SPVDAETHST ISSEFDVDLS 180 KSNVSTKTQN SSVGESATDT FPENQSSVQS HVDLVQSTKN SSMTSNNSTK AKRLGRVRPI 240 SISEMNKLLH QNRLHSHAMK PRWSSVRDQE LLFVKSQIEN APIVNSGREL YAPLYRNISM 300 FKRSYELMEN MLKIYIYNEG DKPIFHHPNL KGIYASEGWF MKLLERNKQF VVKNPLEAHM 360 FYLPFSSLVL RKTLIQPHWV LAEYLKNYVE LIAGKYRFWN RTGGADHFLV ACHDWALEET 420 KKYMGTCIRA LCNTDAARSF KIGKDVSLPV TYIRFEDNPV RSLGGKPPSK RPFLAFFAGS 480 MHGHVRPILL RHWENKDPDM KIFGRLPPSE KPSYVQYMKS SKYCICAKGY EVHTPRVVEA 540 IFHECVPVII SDNYVPPFFE VLKWETFSVF ILEKDIPNLK NVLLSIPKKK YLELQSRVKK 600 VQKHFLWHKN PVKHDVFYMT LHSIWYNRVF QISV* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-63 | 312 | 586 | 297 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CBI28021.1 | 0 | 7 | 632 | 7 | 662 | unnamed protein product [Vitis vinifera] |
RefSeq | XP_002280595.1 | 0 | 7 | 632 | 5 | 660 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002281263.1 | 0 | 6 | 634 | 4 | 668 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002309547.1 | 0 | 184 | 632 | 12 | 468 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002514248.1 | 0 | 6 | 632 | 6 | 673 | catalytic, putative [Ricinus communis] |