Basic Information | |
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Species | Aquilegia coerulea |
Cazyme ID | Aquca_002_00625.1 |
Family | AA3 |
Protein Properties | Length: 531 Molecular Weight: 58397.4 Isoelectric Point: 5.839 |
Chromosome | Chromosome/Scaffold: 2 Start: 4938807 End: 4940673 |
Description | Glucose-methanol-choline (GMC) oxidoreductase family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
AA3 | 15 | 526 | 0 |
SQDHGVLNIISNVEEIQGKSFDYIVVGGGTSGCPLAATLSERFTVLLVERGGSPFEDPLIMEKKNFCKPLFQSNELTSTAQIVISEEGVVNFRGRVLGGS TTINGGVYSRTSEEHIEKAGWDRKLVKEAYAWVESKMVFEPKTLSPFQKNAKDIFVEAELLPFNGFCLEHVEGTKITGTLFDENEKRHCSAHLLEAGDRN KLTVLLNATVKNIIFSQGNGKPRAHGIKFINSYDNNVDDSYEVYLNQPIIDSDSWGDIILSAGAMGSPQILMLSGIGPPGHLDKFNITPLINAPQVGQDI SDNPSICFALDPMDVPNLTTEPSQVVAITKNAKFLIQIGGIRGTNTKQGRTIQAKLSHPRSKGKLELKTTNPRQNPSLKFNYLLEKTDLDECVEMVHEIQ RVVRSMDLCVGTNYSEKVAKTIADRLEQDNFVTEGTSTEEQLRHFCKIYRTSYLHSNGGCRVGSVVDKDYKVYGVEGLRVLDASTLNDLMGTSPMGTLLM LGRYVGIQMLRE |
Full Sequence |
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Protein Sequence Length: 531 Download |
MSLESSSLLS ASSMSQDHGV LNIISNVEEI QGKSFDYIVV GGGTSGCPLA ATLSERFTVL 60 LVERGGSPFE DPLIMEKKNF CKPLFQSNEL TSTAQIVISE EGVVNFRGRV LGGSTTINGG 120 VYSRTSEEHI EKAGWDRKLV KEAYAWVESK MVFEPKTLSP FQKNAKDIFV EAELLPFNGF 180 CLEHVEGTKI TGTLFDENEK RHCSAHLLEA GDRNKLTVLL NATVKNIIFS QGNGKPRAHG 240 IKFINSYDNN VDDSYEVYLN QPIIDSDSWG DIILSAGAMG SPQILMLSGI GPPGHLDKFN 300 ITPLINAPQV GQDISDNPSI CFALDPMDVP NLTTEPSQVV AITKNAKFLI QIGGIRGTNT 360 KQGRTIQAKL SHPRSKGKLE LKTTNPRQNP SLKFNYLLEK TDLDECVEMV HEIQRVVRSM 420 DLCVGTNYSE KVAKTIADRL EQDNFVTEGT STEEQLRHFC KIYRTSYLHS NGGCRVGSVV 480 DKDYKVYGVE GLRVLDASTL NDLMGTSPMG TLLMLGRYVG IQMLRERGVE * 540 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam05199 | GMC_oxred_C | 1.0e-21 | 373 | 516 | 149 | + GMC oxidoreductase. This domain found associated with pfam00732. | ||
TIGR01810 | betA | 1.0e-21 | 36 | 317 | 314 | + choline dehydrogenase. Choline dehydrogenase catalyzes the conversion of exogenously supplied choline into the intermediate glycine betaine aldehyde, as part of a two-step oxidative reaction leading to the formation of osmoprotectant betaine. This enzymatic system can be found in both gram-positive and gram-negative bacteria. As in Escherichia coli , Staphylococcus xylosus , and Sinorhizobium meliloti, this enzyme is found associated in a transciptionally co-induced gene cluster with betaine aldehyde dehydrogenase, the second catalytic enzyme in this reaction. Other gram-positive organisms have been shown to employ a different enzymatic system, utlizing a soluable choline oxidase or type III alcohol dehydrogenase instead of choline dehydrogenase. This enzyme is a member of the GMC oxidoreductase family (pfam00732 and pfam05199), sharing a common evoluntionary origin and enzymatic reaction with alcohol dehydrogenase. Outgrouping from this model, Caulobacter crescentus shares sequence homology with choline dehydrogenase, yet other genes participating in this enzymatic reaction have not currently been identified [Cellular processes, Adaptations to atypical conditions]. | ||
COG2303 | BetA | 4.0e-39 | 31 | 528 | 580 | + Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism] | ||
TIGR03970 | Rv0697 | 4.0e-40 | 36 | 516 | 539 | + dehydrogenase, Rv0697 family. This model describes a set of dehydrogenases belonging to the glucose-methanol-choline oxidoreductase (GMC oxidoreductase) family. Members of the present family are restricted to Actinobacterial genome contexts containing also members of families TIGR03962 and TIGR03969 (the mycofactocin system), and are proposed to be uniform in function. | ||
PLN02785 | PLN02785 | 5.0e-138 | 34 | 527 | 547 | + Protein HOTHEAD |
Gene Ontology | |
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GO Term | Description |
GO:0016614 | oxidoreductase activity, acting on CH-OH group of donors |
GO:0050660 | flavin adenine dinucleotide binding |
GO:0055114 | oxidation-reduction process |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | NP_172871.1 | 0 | 23 | 527 | 4 | 483 | glucose-methanol-choline (GMC) oxidoreductase family protein [Arabidopsis thaliana] |
RefSeq | XP_002312249.1 | 0 | 26 | 526 | 4 | 486 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002315047.1 | 0 | 23 | 526 | 7 | 489 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002315048.1 | 0 | 7 | 527 | 22 | 526 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002522448.1 | 0 | 7 | 527 | 22 | 525 | glucose-methanol-choline (gmc) oxidoreductase, putative [Ricinus communis] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 3gdp_B | 0 | 29 | 527 | 22 | 517 | A Chain A, Crystal Structure Of The Nasturtium Seedling Xyloglucanase Isoform Nxg1 |
PDB | 3gdp_A | 0 | 29 | 527 | 22 | 517 | A Chain A, Crystal Structure Of The Nasturtium Seedling Xyloglucanase Isoform Nxg1 |
PDB | 3gdn_B | 0 | 29 | 527 | 22 | 517 | A Chain A, Almond Hydroxynitrile Lyase In Complex With Benzaldehyde |
PDB | 3gdn_A | 0 | 29 | 527 | 22 | 517 | A Chain A, Almond Hydroxynitrile Lyase In Complex With Benzaldehyde |
PDB | 1ju2_B | 0 | 29 | 527 | 22 | 517 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
DR939299 | 282 | 251 | 531 | 0 |
DR939300 | 255 | 19 | 273 | 0 |
JZ007124 | 248 | 104 | 351 | 0 |
DR931779 | 276 | 237 | 512 | 0 |
DR931779 | 22 | 509 | 530 | 0.72 |
Sequence Alignments (This image is cropped. Click for full image.) |
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