| Basic Information | |
|---|---|
| Species | Aquilegia coerulea |
| Cazyme ID | Aquca_005_00561.2 |
| Family | GH31 |
| Protein Properties | Length: 1095 Molecular Weight: 122046 Isoelectric Point: 6.6832 |
| Chromosome | Chromosome/Scaffold: 5 Start: 7058441 End: 7081607 |
| Description | heteroglycan glucosidase 1 |
| View CDS | |
| External Links |
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| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GH31 | 279 | 690 | 0 |
| SPTAALISLSHAIGTVLMPPKWSLGYHQCRWSYDSAVRVLQVAKTFRKKGIPCDVVWMDIDYMDGFRCFTFDKERFSNPQVLVNDLHLNGFKAIWMLDPG IKQEEGYFVYDSGSKNDVWVLKEDGKPYVGEVWPGACVFPDFTQRKTRSWWAELVKEFMSNGVDGIWNDMNEPAVFKTVTKTMPSSNIHRGDAELGGCQN HLHYHNVYGMLMARSTYEGMRLGKENKRPFVLTRAGFIGSQRYAATWTGDNLSNWEHLHMSLSMVLQLGLSGQALSGPDIGGFAGNATPKLFGRWMGMGA MFPFCRGHSEAGTVDHEPWSFGEECEEVCRLALLRRYRLIPHIYTLFYMAHTKGTPVAAPTFFTDPKDPRLRKVENSFLLGPVLIHASTVPVGGSDQLQQ VFPRGIWLRFDF | |||
| Full Sequence |
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| Protein Sequence Length: 1095 Download |
| EMKPLSGSLS LSLLPITSCC KGRGRGRGRG RGRRRGSSTS TSSGQVVLLW CSNSNSSSRV 60 STTWIRSSLF FNYSIHSISI HHLPSPIFFR HRYIHCVSGE NLLFTMAEFE GKEVNIAGNM 120 IYEPILEEGV FRFDCSGSDR SAAFPSLSFT DTKLRDTPVM IHKVPVYLPT FKCVNEQQIV 180 SIKLPIGTSF YGTGEVSGQL ERTGKRIFTW NTDAWGYGSG TTSLYQSHPW VLAVLPSGEA 240 LGVLADTTHR CEIDLRKEST IQILAPASYP VITFGPFASP TAALISLSHA IGTVLMPPKW 300 SLGYHQCRWS YDSAVRVLQV AKTFRKKGIP CDVVWMDIDY MDGFRCFTFD KERFSNPQVL 360 VNDLHLNGFK AIWMLDPGIK QEEGYFVYDS GSKNDVWVLK EDGKPYVGEV WPGACVFPDF 420 TQRKTRSWWA ELVKEFMSNG VDGIWNDMNE PAVFKTVTKT MPSSNIHRGD AELGGCQNHL 480 HYHNVYGMLM ARSTYEGMRL GKENKRPFVL TRAGFIGSQR YAATWTGDNL SNWEHLHMSL 540 SMVLQLGLSG QALSGPDIGG FAGNATPKLF GRWMGMGAMF PFCRGHSEAG TVDHEPWSFG 600 EECEEVCRLA LLRRYRLIPH IYTLFYMAHT KGTPVAAPTF FTDPKDPRLR KVENSFLLGP 660 VLIHASTVPV GGSDQLQQVF PRGIWLRFDF DDAHPDLPTL YLQGGSMIPV GPPIQHVGEA 720 NPTDDLSLIM ALNEEGKAEG LIFEDDGDGN EFNQGEYLLT YYVAELQSSV VTVKISKTEG 780 SWKRPARRLH VQLLLGGGAM LDAWGKDGEV IEIKMPSEAE VSTLISTSEK QCKIRMESAK 840 PIPDVEEVSG KKGMELSKTP VELKSGDWLL KVVPWIGGRM ISMMHLPSGT QWLHSRVEVD 900 GYEEYGGVEY RSCGCSEDYA VTDRRNLEQA GETESLKLEG DISGGLVLER QIKILKDDPK 960 VLRIDSGIIA RNVGAGSGGF SRLVCLRVHP MFTLLHPTEV FVTFVSINGS NHEVWPESGE 1020 QLFEGDLRPN GEWMLVDRCL GLGLVNKFNI DEVYKCLIHW GTGTVNLELW SEERPVSKQS 1080 PLRISHAYEV RHIS* 1140 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| cd06603 | GH31_GANC_GANAB_alpha | 2.0e-124 | 292 | 632 | 345 | + This family includes the closely related glycosyl hydrolase family 31 (GH31) isozymes, neutral alpha-glucosidase C (GANC) and the alpha subunit of heterodimeric neutral alpha-glucosidase AB (GANAB). Initially distinguished on the basis of differences in electrophoretic mobility in starch gel, GANC and GANAB have been shown to have other differences, including those of substrate specificity. GANC and GANAB are key enzymes in glycogen metabolism that hydrolyze terminal, non-reducing 1,4-linked alpha-D-glucose residues from glycogen in the endoplasmic reticulum. The GANC/GANAB family includes the alpha-glucosidase II (ModA) from Dictyostelium discoideum as well as the alpha-glucosidase II (GLS2, or ROT2 - Reversal of TOR2 lethality protein 2) from Saccharomyces cerevisiae. | ||
| COG1501 | COG1501 | 3.0e-138 | 176 | 779 | 628 | + Alpha-glucosidases, family 31 of glycosyl hydrolases [Carbohydrate transport and metabolism] | ||
| pfam01055 | Glyco_hydro_31 | 1.0e-162 | 272 | 708 | 457 | + Glycosyl hydrolases family 31. Glycosyl hydrolases are key enzymes of carbohydrate metabolism. Family 31 comprises of enzymes that are, or similar to, alpha- galactosidases. | ||
| PLN02763 | PLN02763 | 0 | 116 | 1093 | 978 | + hydrolase, hydrolyzing O-glycosyl compounds | ||
| cd06604 | GH31_glucosidase_II_MalA | 0 | 292 | 632 | 342 | + Alpha-glucosidase II (alpha-D-glucoside glucohydrolase) is a glycosyl hydrolase family 31 (GH31) enzyme, found in bacteria and plants, which has exo-alpha-1,4-glucosidase and oligo-1,6-glucosidase activities. Alpha-glucosidase II has been characterized in Bacillus thermoamyloliquefaciens where it forms a homohexamer. This family also includes the MalA alpha-glucosidase from Sulfolobus sulfataricus and the AglA alpha-glucosidase from Picrophilus torridus. MalA is part of the carbohydrate-metabolizing machinery that allows this organism to utilize carbohydrates, such as maltose, as the sole carbon and energy source. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004553 | hydrolase activity, hydrolyzing O-glycosyl compounds |
| GO:0005975 | carbohydrate metabolic process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CBI37476.1 | 0 | 89 | 1093 | 50 | 1056 | unnamed protein product [Vitis vinifera] |
| RefSeq | NP_566736.1 | 0 | 119 | 1090 | 17 | 987 | HGL1 (heteroglycan glucosidase 1); hydrolase, hydrolyzing O-glycosyl compounds [Arabidopsis thaliana] |
| RefSeq | XP_002263148.1 | 0 | 120 | 1093 | 1 | 972 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002326592.1 | 0 | 116 | 1094 | 15 | 1001 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002519886.1 | 0 | 106 | 1094 | 1 | 991 | neutral alpha-glucosidase ab precursor, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3w38_A | 0 | 164 | 747 | 179 | 798 | A Chain A, Structural Insights Into The Processivity Of Endopolygalacturonase I From Aspergillus Niger |
| PDB | 3w37_A | 0 | 164 | 747 | 179 | 798 | A Chain A, Structural Insights Into The Processivity Of Endopolygalacturonase I From Aspergillus Niger |
| PDB | 2g3n_F | 0 | 179 | 710 | 53 | 610 | A Chain A, Structural Insights Into The Processivity Of Endopolygalacturonase I From Aspergillus Niger |
| PDB | 2g3n_E | 0 | 179 | 710 | 53 | 610 | A Chain A, Structural Insights Into The Processivity Of Endopolygalacturonase I From Aspergillus Niger |
| PDB | 2g3n_D | 0 | 179 | 710 | 53 | 610 | A Chain A, Structural Insights Into The Processivity Of Endopolygalacturonase I From Aspergillus Niger |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| HO779383 | 650 | 447 | 1090 | 0 |
| DT727274 | 299 | 379 | 677 | 0 |
| DT747784 | 275 | 749 | 1023 | 0 |
| HO783906 | 313 | 329 | 641 | 0 |
| HO783906 | 77 | 575 | 651 | 0.0005 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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