| Basic Information | |
|---|---|
| Species | Aquilegia coerulea |
| Cazyme ID | Aquca_006_00421.1 |
| Family | GT47 |
| Protein Properties | Length: 372 Molecular Weight: 43409.9 Isoelectric Point: 7.9178 |
| Chromosome | Chromosome/Scaffold: 6 Start: 8480784 End: 8481899 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
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| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| GT47 | 55 | 301 | 5e-35 |
| NFKIYIYNDINNQTTFPSNIESLFHTSLLESSFITKNPNEAHFFYLYFSPSSSYKSISGKIKDLQIQYPFWNRTLGADHFYLSCNGIGYESDRNIVELKK NSVQISCFSPMKNDESHRFIPHKDLSLPPMIAIDLQMDTVNIVPISKKKYFGYFNNRDIDNLDPVIDFIEELRNDPDFMTDTEPYDYDWVSNIKFCLFFF TDKFVSISGFEKALRYGCVPVVITDRSIVNLPFVDVLKWTEIAVFVD | |||
| Full Sequence |
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| Protein Sequence Length: 372 Download |
| MEYRLLFLLL LLLSISAFLQ LKPLTATTTT QTTSSSSPYL SSSLFLPNYQ KMLQNFKIYI 60 YNDINNQTTF PSNIESLFHT SLLESSFITK NPNEAHFFYL YFSPSSSYKS ISGKIKDLQI 120 QYPFWNRTLG ADHFYLSCNG IGYESDRNIV ELKKNSVQIS CFSPMKNDES HRFIPHKDLS 180 LPPMIAIDLQ MDTVNIVPIS KKKYFGYFNN RDIDNLDPVI DFIEELRNDP DFMTDTEPYD 240 YDWVSNIKFC LFFFTDKFVS ISGFEKALRY GCVPVVITDR SIVNLPFVDV LKWTEIAVFV 300 DIKGGLKNLQ KVVGHRCEGE KYEKMRELGM KASKHFVWNH LSPQPHDAFY SVLYQLWLRR 360 HTIRYTRREI I* |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 3.0e-22 | 56 | 303 | 281 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | XP_001753053.1 | 1.4013e-45 | 39 | 368 | 115 | 462 | predicted protein [Physcomitrella patens subsp. patens] |
| RefSeq | XP_002282317.1 | 0 | 13 | 371 | 6 | 360 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002311191.1 | 0 | 14 | 371 | 3 | 345 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002316258.1 | 0 | 18 | 371 | 7 | 339 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002524235.1 | 0 | 43 | 371 | 33 | 337 | conserved hypothetical protein [Ricinus communis] |
