y
Basic Information | |
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Species | Aquilegia coerulea |
Cazyme ID | Aquca_009_00090.1 |
Family | GT47 |
Protein Properties | Length: 482 Molecular Weight: 55787.6 Isoelectric Point: 7.9699 |
Chromosome | Chromosome/Scaffold: 9 Start: 518578 End: 522418 |
Description | exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 90 | 405 | 0 |
PLKVFMYDMPPEFHFELVGWKAEGDNVWPDIQTKIPEYPGGLNLQHSIEYWLTLDLLSSRFRDPKGVYSAVRVFNSSEADVVFVPFFSSVSYNRHSKLVR PQKKSHNKLLQEKLVSYLTSQEEWKRSGGRDHIVIAHHPNSMLDARMQLWPAMFILSDFGRYPPNVANVEKDVIAPYRHVIGSFINDSSGFDDRPTLLYF QGAIYRKDGGIIRQELYYLLKDEKDVHFSFGSIQKGGIREATKGMHSSKFCLNIAGDTPSSNRLFDAIASHCVPVIISDEIELPYEDILNYSEFSISVRM SDAVKENFLIKLIRSI |
Full Sequence |
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Protein Sequence Length: 482 Download |
MADRNSPHLV GFISRKFLCC LFTLTTFFFI FSWFFVFRST GQPQFIDHSL LPNSKLFSTI 60 ENNEETQTSV QNEIQSSSIP YLNCDSNKMP LKVFMYDMPP EFHFELVGWK AEGDNVWPDI 120 QTKIPEYPGG LNLQHSIEYW LTLDLLSSRF RDPKGVYSAV RVFNSSEADV VFVPFFSSVS 180 YNRHSKLVRP QKKSHNKLLQ EKLVSYLTSQ EEWKRSGGRD HIVIAHHPNS MLDARMQLWP 240 AMFILSDFGR YPPNVANVEK DVIAPYRHVI GSFINDSSGF DDRPTLLYFQ GAIYRKDGGI 300 IRQELYYLLK DEKDVHFSFG SIQKGGIREA TKGMHSSKFC LNIAGDTPSS NRLFDAIASH 360 CVPVIISDEI ELPYEDILNY SEFSISVRMS DAVKENFLIK LIRSIGKDEW TRMWNKLKEI 420 ERFFEYQYPS QQDDAVQMIW QAVARKVPAI KLKLHRSQRF DRSDVGRERT LTSVPWSKHN 480 S* 540 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-51 | 90 | 405 | 326 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CAN68950.1 | 0 | 1 | 479 | 1 | 486 | hypothetical protein [Vitis vinifera] |
RefSeq | NP_190126.1 | 0 | 1 | 474 | 3 | 469 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002268382.1 | 0 | 1 | 479 | 1 | 486 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002319201.1 | 0 | 1 | 460 | 3 | 449 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002530948.1 | 0 | 1 | 475 | 1 | 494 | catalytic, putative [Ricinus communis] |