| Basic Information | |
|---|---|
| Species | Aquilegia coerulea |
| Cazyme ID | Aquca_009_00245.1 |
| Family | GT47 |
| Protein Properties | Length: 765 Molecular Weight: 87087.2 Isoelectric Point: 6.3139 |
| Chromosome | Chromosome/Scaffold: 9 Start: 1337077 End: 1343901 |
| Description | exostosin family protein |
| View CDS | |
| External Links |
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| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| GT47 | 335 | 670 | 0 |
| KKRPLIYVYDLPPEFNSHLLEGRHFRFECVNRIYTDQNATFWTDQLYGSQMALYESILASPYRTLNGEEADYFFVPVLDSCIITRADDAPHLSLRSHLGL RSSLTLEFYKKAYDHITEKYPFWNRSSGKDHIWHDVSSLGNTNSKHNHSTTAYWADNWDGIPSTRRGNHPCFDPEKDLVLPAWKQPDPGSLRLKLWSRPR KERTKFFYFNGNLGPAYEHGRPEATYSMGIRQKLAKEFGSSPDKEGKLGNQHAEDVIVTPLRSDNYYEDLANSLFCGVLPGDGWSGRMEDSVLHGCIPVI IQDGIFLPYENVLNYESFAVRIREDDIPNLISTLRG | |||
| Full Sequence |
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| Protein Sequence Length: 765 Download |
| MTFTVQKWKF SWSLVAVVAS LVALVSIVHL FLFPLAPSSF GYLGRQIQSF SLPKNGSQQP 60 EVNLHQQYPA DLHKAVVYQG APWKEEIGRW LSGCDSITRK TAIVERIGGK TCKSDCNGQG 120 ICNRELGQCR CFHGYAGEGC SERLQLECNH PGSQEQPYGP WVVSICSAYC DTTRAMCFCG 180 EGTKYPNRPV AEACGFQSIL PSEPNGPKLT DWAKADLENI FTTNSSKPGW CNVDPEEAYA 240 SKVKSKDECD CKYDCHFGRF CEIPVECVCL NQCSHHGYCR GGFCQCDSGW YGTDCSIPSA 300 LSSVQEWPQW LRPATLHVPD NAHLTIDNID AVVEKKRPLI YVYDLPPEFN SHLLEGRHFR 360 FECVNRIYTD QNATFWTDQL YGSQMALYES ILASPYRTLN GEEADYFFVP VLDSCIITRA 420 DDAPHLSLRS HLGLRSSLTL EFYKKAYDHI TEKYPFWNRS SGKDHIWHDV SSLGNTNSKH 480 NHSTTAYWAD NWDGIPSTRR GNHPCFDPEK DLVLPAWKQP DPGSLRLKLW SRPRKERTKF 540 FYFNGNLGPA YEHGRPEATY SMGIRQKLAK EFGSSPDKEG KLGNQHAEDV IVTPLRSDNY 600 YEDLANSLFC GVLPGDGWSG RMEDSVLHGC IPVIIQDGIF LPYENVLNYE SFAVRIREDD 660 IPNLISTLRG FNETEIEFML ANVRMIWQRF LYRDSVLLEA ERQKSRYGHV DDWVVEFISL 720 NEDDVFSTFI QVLHYKLHND PWRRKLGYLQ KDFGLPKECV QSTN* |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam00053 | Laminin_EGF | 0.009 | 115 | 142 | 32 | + Laminin EGF-like (Domains III and V). This family is like pfam00008 but has 8 conserved cysteines instead of six. | ||
| pfam07974 | EGF_2 | 0.005 | 114 | 140 | 27 | + EGF-like domain. This family contains EGF domains found in a variety of extracellular proteins. | ||
| cd00054 | EGF_CA | 0.005 | 266 | 295 | 34 | + Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements. | ||
| pfam07974 | EGF_2 | 0.001 | 267 | 295 | 31 | + EGF-like domain. This family contains EGF domains found in a variety of extracellular proteins. | ||
| pfam03016 | Exostosin | 3.0e-62 | 335 | 671 | 342 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CAN80640.1 | 0 | 1 | 754 | 1 | 809 | hypothetical protein [Vitis vinifera] |
| EMBL | CBI29877.1 | 0 | 1 | 763 | 29 | 821 | unnamed protein product [Vitis vinifera] |
| RefSeq | NP_191322.3 | 0 | 3 | 764 | 2 | 793 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_002277596.1 | 0 | 1 | 764 | 1 | 794 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002308967.1 | 0 | 3 | 764 | 2 | 793 | predicted protein [Populus trichocarpa] |
