| Basic Information | |
|---|---|
| Species | Aquilegia coerulea |
| Cazyme ID | Aquca_009_00755.3 |
| Family | GT35 |
| Protein Properties | Length: 847 Molecular Weight: 96072.2 Isoelectric Point: 6.3147 |
| Chromosome | Chromosome/Scaffold: 9 Start: 4552884 End: 4559374 |
| Description | alpha-glucan phosphorylase 2 |
| View CDS | |
| External Links |
|---|
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT35 | 118 | 841 | 0 |
| ALNKLGHDLENITEQEKDAALGNGGLGRLASCFLDSMATLNLPAWGYGLRYRYGLFKQKITKDGQEETAENWLEKFSPWEVVRHDVIYPVRFFGRVEVNP TGSRKWVEGEVIQALAYDVPIPGYKTKNTISLRLWEAKAVAEDFNLFEFNDGQYESAAQLHSKAQQICAVLYPGDATEEGKLLRLKQQFFLCSASLQDII FRFKERRDGKGSWQWSEFPSKVAVQLNDTHPTLAIPELMRLLMDDEGLGWDEAWDVTTRTIAYTNHTVLPEALEKWSLAVMRKLLPRHIEIIEEIDKRFV AMVHSTQPDLESKLPSLCILDTSNPQKSVVRMANLCVVTAHTVNGVAQLHSDILKAELFVDYVSIWPTKFQNKTNGITPRRWLRYCNPELSSIITKWLKT DEWVTNLDLLTKLRQFADNEDLQAEWASAKMANKKRLADYILQVTGLSIDPNSLFDIQVKRIHEYKRQLLNILGAIYRYKKLKEMNPDERAKTTPRTIMI GGKAFATYTNAKRIVKLVNDVGAVVNTDPEVNNYLKVVFVPNYNVSVAEVLIPGSELSQHISTAGMEASGTSNMKFALNGCLIIGTLDGANVEIREEIGK ENFFLFGAEADEVPKLRKDRENGLFKPDPRFEEAKQFIRSGAFGTYDYNPLLDSLEGNSGYGRGDYFLVGHDFPSYMDAQAKVDEAYKDQKRWLKMSILS TAGSGKFSSDRTIAQYAKEIWNIE | |||
| Full Sequence |
|---|
| Protein Sequence Length: 847 Download |
| MATATKEHNG SVPIDTTTKI PAEAHPLAEK PAEIASNINY HAKFSPHFSP FKFEPEQAYY 60 ATAESVRDRL IQQWNETYNH FHKVDPKQTY YLSMEYLQGR ALTNAIGNLD IQHAYADALN 120 KLGHDLENIT EQEKDAALGN GGLGRLASCF LDSMATLNLP AWGYGLRYRY GLFKQKITKD 180 GQEETAENWL EKFSPWEVVR HDVIYPVRFF GRVEVNPTGS RKWVEGEVIQ ALAYDVPIPG 240 YKTKNTISLR LWEAKAVAED FNLFEFNDGQ YESAAQLHSK AQQICAVLYP GDATEEGKLL 300 RLKQQFFLCS ASLQDIIFRF KERRDGKGSW QWSEFPSKVA VQLNDTHPTL AIPELMRLLM 360 DDEGLGWDEA WDVTTRTIAY TNHTVLPEAL EKWSLAVMRK LLPRHIEIIE EIDKRFVAMV 420 HSTQPDLESK LPSLCILDTS NPQKSVVRMA NLCVVTAHTV NGVAQLHSDI LKAELFVDYV 480 SIWPTKFQNK TNGITPRRWL RYCNPELSSI ITKWLKTDEW VTNLDLLTKL RQFADNEDLQ 540 AEWASAKMAN KKRLADYILQ VTGLSIDPNS LFDIQVKRIH EYKRQLLNIL GAIYRYKKLK 600 EMNPDERAKT TPRTIMIGGK AFATYTNAKR IVKLVNDVGA VVNTDPEVNN YLKVVFVPNY 660 NVSVAEVLIP GSELSQHIST AGMEASGTSN MKFALNGCLI IGTLDGANVE IREEIGKENF 720 FLFGAEADEV PKLRKDRENG LFKPDPRFEE AKQFIRSGAF GTYDYNPLLD SLEGNSGYGR 780 GDYFLVGHDF PSYMDAQAKV DEAYKDQKRW LKMSILSTAG SGKFSSDRTI AQYAKEIWNI 840 EECIVP* 900 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| cd04300 | GT1_Glycogen_Phosphorylase | 0 | 35 | 840 | 815 | + This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of oligosaccharides into glucose-1-phosphate units. They are important allosteric enzymes in carbohydrate metabolism. The allosteric control mechanisms of yeast and mammalian members of this family are different from that of bacterial members. The members of this family belong to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. | ||
| TIGR02093 | P_ylase | 0 | 38 | 840 | 811 | + glycogen/starch/alpha-glucan phosphorylases. This family consists of phosphorylases. Members use phosphate to break alpha 1,4 linkages between pairs of glucose residues at the end of long glucose polymers, releasing alpha-D-glucose 1-phosphate. The nomenclature convention is to preface the name according to the natural substrate, as in glycogen phosphorylase, starch phosphorylase, maltodextrin phosphorylase, etc. Name differences among these substrates reflect differences in patterns of branching with alpha 1,6 linkages. Members include allosterically regulated and unregulated forms. A related family, TIGR02094, contains examples known to act well on particularly small alpha 1,4 glucans, as may be found after import from exogenous sources [Energy metabolism, Biosynthesis and degradation of polysaccharides]. | ||
| pfam00343 | Phosphorylase | 0 | 118 | 842 | 730 | + Carbohydrate phosphorylase. The members of this family catalyze the formation of glucose 1-phosphate from one of the following polyglucoses; glycogen, starch, glucan or maltodextrin. | ||
| PRK14986 | PRK14986 | 0 | 61 | 841 | 790 | + glycogen phosphorylase; Provisional | ||
| PRK14985 | PRK14985 | 0 | 91 | 838 | 757 | + maltodextrin phosphorylase; Provisional | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004645 | phosphorylase activity |
| GO:0005975 | carbohydrate metabolic process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAM29154.1 | 0 | 4 | 843 | 2 | 837 | starch phosphorylase type H [Citrus hybrid cultivar] |
| DDBJ | BAG31926.1 | 0 | 4 | 846 | 2 | 843 | alpha-1,4-glucan phosphorylase H isozyme [Cucurbita maxima] |
| RefSeq | XP_002280732.1 | 0 | 1 | 846 | 1 | 843 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002313399.1 | 0 | 10 | 846 | 18 | 853 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002520435.1 | 0 | 1 | 846 | 1 | 849 | glycogen phosphorylase, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 1z8d_A | 0 | 28 | 841 | 22 | 829 | A Chain A, Crystal Structure Of Human Muscle Glycogen Phosphorylase A With Amp And Glucose |
| PDB | 4el5_A | 0 | 28 | 841 | 10 | 817 | A Chain A, Crystal Structure Of Human Muscle Glycogen Phosphorylase A With Amp And Glucose |
| PDB | 4el0_A | 0 | 28 | 841 | 10 | 817 | A Chain A, Crystal Structure Of Human Muscle Glycogen Phosphorylase A With Amp And Glucose |
| PDB | 4eky_A | 0 | 28 | 841 | 10 | 817 | A Chain A, Crystal Structure Of Human Muscle Glycogen Phosphorylase A With Amp And Glucose |
| PDB | 4eke_A | 0 | 28 | 841 | 10 | 817 | A Chain A, Crystal Structure Of Human Muscle Glycogen Phosphorylase A With Amp And Glucose |
| Hydropathy |
|---|
 |
| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| HO782200 | 413 | 174 | 586 | 0 |
| HO418036 | 539 | 244 | 762 | 0 |
| HO586252 | 553 | 292 | 843 | 0 |
| HO613954 | 499 | 397 | 847 | 0 |
| GT044838 | 338 | 480 | 817 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
|---|
 |
