Basic Information | |
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Species | Aquilegia coerulea |
Cazyme ID | Aquca_011_00072.1 |
Family | GT47 |
Protein Properties | Length: 471 Molecular Weight: 54263.4 Isoelectric Point: 9.1697 |
Chromosome | Chromosome/Scaffold: 11 Start: 1789030 End: 1791903 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 138 | 422 | 0 |
EKRFKVYVYEEGDRPIVHGGPCKDIYTSEGRFIHEMELENTKFKTRDARYAHVYFMPFSVSMMVKYLYKPNSFDKSPLLRFVSDYIRVISTKYPFWNKTQ GANHFMLSCHDWGPDSSRGNPLLYNNSIRVLCNANTSEGFDPRKDATLPEIDLYDGNMSPDLISIPPDNAPRPHLAFFAGGLHGPIRPILFRHWKAKDPD IIVYEYLPKNLKYYSFMLQSKFCLCPSGYEVASPRIVEAIYAQCVPVLLSEHYVPPFSDVLRWEAFSVQVKVSDIPNLKEILNAI |
Full Sequence |
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Protein Sequence Length: 471 Download |
MEVSHGLKVF SLSLFLLLCI IYFFSSNKLN HQYTKFDDQL QQTQFVRSSV ANHISSALYG 60 SLTTNGSIEN RYRNPTFIRK VGKLSDSEKL ELGLAKARVA IRSAIKLNIS ASDDDEDAPR 120 GVVYRNPSAF YQSYLEMEKR FKVYVYEEGD RPIVHGGPCK DIYTSEGRFI HEMELENTKF 180 KTRDARYAHV YFMPFSVSMM VKYLYKPNSF DKSPLLRFVS DYIRVISTKY PFWNKTQGAN 240 HFMLSCHDWG PDSSRGNPLL YNNSIRVLCN ANTSEGFDPR KDATLPEIDL YDGNMSPDLI 300 SIPPDNAPRP HLAFFAGGLH GPIRPILFRH WKAKDPDIIV YEYLPKNLKY YSFMLQSKFC 360 LCPSGYEVAS PRIVEAIYAQ CVPVLLSEHY VPPFSDVLRW EAFSVQVKVS DIPNLKEILN 420 AIPEEQYKKL KEGVKAVRKH FVLNQPPKRF DVFHMILHSI WIRRLNVQLS * 480 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 1.0e-61 | 137 | 422 | 304 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CBI21064.1 | 0 | 70 | 470 | 74 | 478 | unnamed protein product [Vitis vinifera] |
RefSeq | NP_197913.4 | 0 | 11 | 470 | 20 | 480 | catalytic [Arabidopsis thaliana] |
RefSeq | XP_002285237.1 | 0 | 137 | 470 | 1 | 334 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002324871.1 | 0 | 137 | 469 | 1 | 333 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002515489.1 | 0 | 14 | 470 | 22 | 481 | catalytic, putative [Ricinus communis] |