Basic Information | |
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Species | Aquilegia coerulea |
Cazyme ID | Aquca_011_00571.1 |
Family | GT47 |
Protein Properties | Length: 531 Molecular Weight: 61462 Isoelectric Point: 10.4214 |
Chromosome | Chromosome/Scaffold: 11 Start: 6340022 End: 6347441 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 194 | 479 | 0 |
ILKVYIYKEGKRPIFHQPHLRGIYASEGWFLKLMEENRQFVTRDPKRAHLFYLPYSARQLQLALYVPDSHNLKPLSIFLRDHVNMIAAKYPFWNRTRGAD HFLVACHDWGPYTVTEHEELLRNTLKALCNADLSEKIFVPGRDVSLPETTIRRPRKPLRGIGGKRVSQRPILAFFAGNMHGRVRPALLQYWDGKDEDMRI YGPLPNRVARVMSYAVHMKSSRFCICPMGYEVNSPRIVEAIYNECVPVIIADNFVLPFSEVLDWKSFSVVVAEKDIPNLKVILSAI |
Full Sequence |
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Protein Sequence Length: 531 Download |
MKEPRRRYKG YRMNWRKLVC VVAIMTAVGV VLQTYVLPYP LNNLFLVPPV TVSLPEVSNS 60 TYFVKETIPM VSFPSIVTKN SSNIASEIIP SVPVVEVRAE VSSRRGRGRR GRGRGNMNTN 120 KKNPNEPKVV PQPPPKLVVL GQRPIWSLPP DKALLYAKKE LEHAPIVADD PDLYAPLFRN 180 VSIFKRSYEL MESILKVYIY KEGKRPIFHQ PHLRGIYASE GWFLKLMEEN RQFVTRDPKR 240 AHLFYLPYSA RQLQLALYVP DSHNLKPLSI FLRDHVNMIA AKYPFWNRTR GADHFLVACH 300 DWGPYTVTEH EELLRNTLKA LCNADLSEKI FVPGRDVSLP ETTIRRPRKP LRGIGGKRVS 360 QRPILAFFAG NMHGRVRPAL LQYWDGKDED MRIYGPLPNR VARVMSYAVH MKSSRFCICP 420 MGYEVNSPRI VEAIYNECVP VIIADNFVLP FSEVLDWKSF SVVVAEKDIP NLKVILSAIP 480 LRRYLWMQTN VKMLQKHFLW NPRPIRYDLF HMVLHSIWFN RLNQIQIQQQ * 540 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 4.0e-64 | 195 | 479 | 302 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CBI23466.1 | 0 | 11 | 527 | 14 | 535 | unnamed protein product [Vitis vinifera] |
RefSeq | NP_567512.2 | 0 | 131 | 526 | 135 | 532 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002269459.1 | 0 | 11 | 527 | 14 | 535 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002303362.1 | 0 | 146 | 530 | 1 | 386 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002530666.1 | 0 | 1 | 527 | 2 | 525 | catalytic, putative [Ricinus communis] |